RbBP4 Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Rat, Zebrafish, X
• laevis, X
• tropicalis, Chicken, Bovine, Dog, Rabbit, Guinea pig_10141, This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins
• It is present in protein complexes involved in histone acetylation and chromatin assembly
• It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation
• This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing
• It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation
• This protein also seems to be involved in transcriptional repression of E2F-responsive genes
• Three transcript variants encoding different isoforms have been found for this gene.