SPTAN1/Alpha II-spectrin Polyclonal Antibody, Bethyl Laboratories

Description

• The recommended shelf life for this product is 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Zebrafish, X
• tropicalis, Bovine, Dog, Horse, Guinea pig_10141, Pig, Panda, Or Spectrins are a family of filamentous cytoskeletal proteins that function as essential scaffold proteins that stabilize the plasma membrane and organize intracellular organelles
• Spectrins are composed of alpha and beta dimers that associate to form tetramers linked in a head-to-head arrangement
• This gene encodes an alpha spectrin that is specifically expressed in nonerythrocytic cells
• The encoded protein has been implicated in other cellular functions including DNA repair and cell cycle regulation
• Mutations in this gene are the cause of early infantile epileptic encephalopathy-5
• Alternate splicing results in multiple transcript variants.