7144191

CIP2A Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CIP2A

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

Cancerous Inhibitor of Protein Phosphatase 2A , p90

Gene Symbols

CIP2A

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunofluorescence, Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q8TCG1

Gene ID (Entrez)

57650

Immunogen

Between 550 and 600

Primary or Secondary

Primary

Content And Storage

4° C

Gene

CIP2A

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Inhibition of protein phosphatase 2A (PP2A) activity has been identified as a prerequisite for the transformation of human cells
  • The protein, designated Cancerous Inhibitor of PP2A (CIP2A), interacts directly with the oncogenic transcription factor c-Myc, inhibits PP2A activity toward c-Myc serine 62 (S62), and thereby prevents c-Myc proteolytic degradation
  • In addition to its function in c-Myc stabilization, CIP2A promotes anchorage-independent cell growth and in vivo tumor formation
  • The oncogenic activity of CIP2A is demonstrated by transformation of human cells by overexpression of CIP2A
  • Importantly, CIP2A is overexpressed in two common human maligcies, head and neck squamous cell carcinoma (HNSCC) and colon cancer.

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Fischer Scientific

7144191

Rabbit Polyclonal Antibody...


Antigen:
CIP2A

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
Cancerous Inhibitor of Protein Phosphatase 2A , p90

Gene Symbols:
CIP2A

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunofluorescence, Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q8TCG1

Gene ID (Entrez):
57650

Immunogen:
Between 550 and 600

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
CIP2A

Img

Fischer Scientific

7144192

Rabbit Polyclonal Antibody...


Antigen:
CPSF68

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
Cleavage and polyadenylation specific factor 6, CFIM, CFIM68, HPBRII-4, HPBRII-7

Gene Symbols:
__

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunofluorescence, Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q16630, Q6NVF9

Gene ID (Entrez):
11052, 432508

Immunogen:
Between 501 and 551

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
CPSF6

Img

Fischer Scientific

7144194

Rabbit Polyclonal Antibody...


Antigen:
Coronin 2

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
CORONIN-2, coronin-1B

Gene Symbols:
CORO1B

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunofluorescence, Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9BR76

Gene ID (Entrez):
57175

Immunogen:
Between 450 and 489

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
CORO1B

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Fischer Scientific

7144195

Rabbit Polyclonal Antibody...


Antigen:
BRF1

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C

Gene Symbols:
BRF1

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q92994

Gene ID (Entrez):
2972

Immunogen:
Between 627 and 677

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
BRF1