7144264
14-3-3 Sigma Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
14-3-3 Sigma
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
14-3-3 protein sigma, 14-3-3 sigma, epithelial cell marker protein 1
Gene Symbols
SFN
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunofluorescence, Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
P31947
Gene ID (Entrez)
2810
Immunogen
Between 198 and 248
Primary or Secondary
Primary
Content And Storage
4° C
Gene
SFN
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Crab-eating macaque and Wh 14-3-3 sigma (stratifin, SFN, epithelial cell marker protein 1) is a member of a highly conserved family of 14-3-3 proteins that are present in all eukaryotic organisms
- There are 7 known mammalian 14-3-3 isoforms epsilon, beta, zeta, gamma, theta, tau and they play important roles in many biological activities by binding to and altering the subcellular localization and/or stability of key molecules in various signaling cascades
- 14-3-3 sigma was originally characterized as a human mammary epithelium marker and later rediscovered as an important molecule for cell cycle checkpoint regulation
- Recently it has been reported that 14-3-3 sigma may serve as a prognosis marker predicting survival of pancreatic cancer patient treatment
- 14-3-3 sigmais the only 14-3-3 isoform induced by the tumor suppressor protein p53, in response to g-irradiation and other DNA-damaging agents
- 14-3-3 sigmais a p53-regulated inhibitor of G2/M progression and acts as a tumor suppressor gene that is inactivated by methylation of its 5' CpG islands in epithelial tumor cells
- Two isoforms of human 14-3-3 sigma are produced by alternative splicing.
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Antigen: 14-3-3 Sigma
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: 14-3-3 protein sigma, 14-3-3 sigma, epithelial cell marker protein 1
Gene Symbols: SFN
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P31947
Gene ID (Entrez): 2810
Immunogen: Between 198 and 248
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: SFN
Antigen:
14-3-3 Sigma
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
14-3-3 protein sigma, 14-3-3 sigma, epithelial cell marker protein 1
Gene Symbols:
SFN
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P31947
Gene ID (Entrez):
2810
Immunogen:
Between 198 and 248
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
SFN
Antigen: PUS1
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: MLASA1, mitochondrial tRNA pseudouridine synthase A, tRNA pseudouridine synthase A, mitochondrial, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA uridine isomerase I, tRNA-uridine isomerase I
Gene Symbols: PUS1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9Y606
Gene ID (Entrez): 80324
Immunogen: Between 377 and 427
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: PUS1
Antigen:
PUS1
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
MLASA1, mitochondrial tRNA pseudouridine synthase A, tRNA pseudouridine synthase A, mitochondrial, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA uridine isomerase I, tRNA-uridine isomerase I
Gene Symbols:
PUS1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9Y606
Gene ID (Entrez):
80324
Immunogen:
Between 377 and 427
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
PUS1
Antigen: PUS1
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: MLASA1, mitochondrial tRNA pseudouridine synthase A, tRNA pseudouridine synthase A, mitochondrial, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA uridine isomerase I, tRNA-uridine isomerase I
Gene Symbols: PUS1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9Y606
Gene ID (Entrez): 80324
Immunogen: Between 377 and 427
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: PUS1
Antigen:
PUS1
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
MLASA1, mitochondrial tRNA pseudouridine synthase A, tRNA pseudouridine synthase A, mitochondrial, tRNA pseudouridine(38-40) synthase, tRNA pseudouridylate synthase I, tRNA uridine isomerase I, tRNA-uridine isomerase I
Gene Symbols:
PUS1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9Y606
Gene ID (Entrez):
80324
Immunogen:
Between 377 and 427
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
PUS1
Antigen: FBW7
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: AGO, archipelago, Archipelago homolog, archipelago homolog (Drosophila), CDC4, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, hAgo, hCdc4, homolog of C elegans sel-10, SEL10, SEL-10
Gene Symbols: FBXW7
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q969H0
Gene ID (Entrez): 55294
Immunogen: Between 50 and 100
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: FBXW7
Antigen:
FBW7
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
AGO, archipelago, Archipelago homolog, archipelago homolog (Drosophila), CDC4, F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase, F-box and WD-40 domain protein 7 (archipelago homolog, Drosophila), F-box and WD-40 domain-containing protein 7, F-box protein FBW7, F-box protein FBX30, F-box protein SEL-10, FBW6, FBW7, FBX30, FBXO30, FBXW6, FLJ11071, hAgo, hCdc4, homolog of C elegans sel-10, SEL10, SEL-10
Gene Symbols:
FBXW7
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q969H0
Gene ID (Entrez):
55294
Immunogen:
Between 50 and 100
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
FBXW7