7144392
BubR1 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
BubR1
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
BUB1B, Budding Uninhibited by Benzimidazoles 1 beta, hBUBR1, MAD3L
Gene Symbols
BUB1B
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O60566
Gene ID (Entrez)
701
Immunogen
Between 1 and 50
Primary or Secondary
Primary
Content And Storage
4° C
Gene
BUB1B
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Orangutan, Monkey, Gorilla, Chimpanzee and Crab-eating macaque Compromised spindle checkpoints are thought to play an important role in genetic instability that predisposes cells to maligt transformations
- Human cells contain two related checkpoint protein kinases, evolved from the BUB1 gene; hBUBR1 and hBUB1
- They are important components of the spindle checkpoint Both kinases monitor mitotic kinetochore-microtubule interactions
- hBUBR1 is essential for normal mitotic progression as it prevents cells from entering into anaphase too early
- BUBR1 has been detected in human cancers
- It has been identified as a novel binding partner of BCSG1 (Breast Cancer-Specific Gene 1), which has been suggested to accelerate the progression of breast cancer by compromising the mitotic checkpoint control through inactivation of BUBR1.
Compare Similar Items
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Antigen: BubR1
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: BUB1B, Budding Uninhibited by Benzimidazoles 1 beta, hBUBR1, MAD3L
Gene Symbols: BUB1B
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O60566
Gene ID (Entrez): 701
Immunogen: Between 1 and 50
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: BUB1B
Antigen:
BubR1
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
BUB1B, Budding Uninhibited by Benzimidazoles 1 beta, hBUBR1, MAD3L
Gene Symbols:
BUB1B
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O60566
Gene ID (Entrez):
701
Immunogen:
Between 1 and 50
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
BUB1B
Antigen: CASC5
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Gene Symbols: KNL1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8NG31
Gene ID (Entrez): 57082
Immunogen: Between 300 and 350
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KNL1
Antigen:
CASC5
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Protein CASC5, Cancer susceptibility candidate gene 5 protein homolog, Kinetochore-null protein 1, Casc5, Knl1
Gene Symbols:
KNL1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8NG31
Gene ID (Entrez):
57082
Immunogen:
Between 300 and 350
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KNL1
Antigen: MCAK
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: RP11-269F19.1, KNSL6, MCAK, kinesin-like 6; kinesin-like protein 6; kinesin-like protein KIF2C; mitotic centromere-associated kinesin
Gene Symbols: KIF2C
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q99661
Gene ID (Entrez): 11004
Immunogen: Between 50 and 100
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KIF2C
Antigen:
MCAK
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
RP11-269F19.1, KNSL6, MCAK, kinesin-like 6; kinesin-like protein 6; kinesin-like protein KIF2C; mitotic centromere-associated kinesin
Gene Symbols:
KIF2C
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q99661
Gene ID (Entrez):
11004
Immunogen:
Between 50 and 100
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KIF2C
Antigen: MCAK
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: RP11-269F19.1, KNSL6, MCAK, kinesin-like 6; kinesin-like protein 6; kinesin-like protein KIF2C; mitotic centromere-associated kinesin
Gene Symbols: Kif2c
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Mouse
Gene Accession No.: Q922S8
Gene ID (Entrez): 73804
Immunogen: Between 50 and 100
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: Kif2c
Antigen:
MCAK
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
RP11-269F19.1, KNSL6, MCAK, kinesin-like 6; kinesin-like protein 6; kinesin-like protein KIF2C; mitotic centromere-associated kinesin
Gene Symbols:
Kif2c
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Mouse
Gene Accession No.:
Q922S8
Gene ID (Entrez):
73804
Immunogen:
Between 50 and 100
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
Kif2c