7144467
PDZ-RhoGEF Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
PDZ-RhoGEF
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11
Gene Symbols
ARHGEF11
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O15085
Gene ID (Entrez)
9826
Immunogen
Between 1472 and 1522
Primary or Secondary
Primary
Content And Storage
4° C
Gene
ARHGEF11
Related Products
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Gorilla and Chimpanzee ARHGEF11 is a 1527 amino acid protein with tandem dbl homology and pleckstrin homology domains, PDZ domain, two proline rich sequences and a regulatory G protein-signaling (RGS) sequence
- It acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase, but not for RAC1 or CDC42 and acts as GTPase-activating protein (GAP) for GNA12 and GNA13
- It forms a complex with G proteins and stimulates neurite through retraction Rho-dependent signals
- ARHGEF11 increases glutamate transport 4-fold
- It interacts with EAAT4 and modulates its uptake activity and perisynaptic distribution at glutamatergic synapses
- It is known to induce the reorganization of the actin cytoskeleton and its overexpression induces the formation of membrane ruffling and filopodia
- It is ubiquitously expressed, in brain, lung, liver, kidney and skeletal muscle.
Compare Similar Items
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Antigen: PDZ-RhoGEF
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11
Gene Symbols: ARHGEF11
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O15085
Gene ID (Entrez): 9826
Immunogen: Between 1472 and 1522
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: ARHGEF11
Antigen:
PDZ-RhoGEF
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
RP11-356J7.2, GTRAP48, PDZ-RHOGEF, Rho guanine exchange factor (GEF) 11, RhoA-specific guanine nucleotide exchange factor, RhoGEF glutamate transport modulator, glutamate transporter EAAT4-associated protein 48, rho guanine nucleotide exchange factor 11
Gene Symbols:
ARHGEF11
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O15085
Gene ID (Entrez):
9826
Immunogen:
Between 1472 and 1522
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
ARHGEF11
Antigen: KSRP
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: KHE3
Gene Symbols: __
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q3U0V1, Q92945
Gene ID (Entrez): 16549, 8570
Immunogen: Between 100 and 150
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KHSRP
Antigen:
KSRP
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
KHE3
Gene Symbols:
__
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q3U0V1, Q92945
Gene ID (Entrez):
16549, 8570
Immunogen:
Between 100 and 150
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KHSRP
Antigen: Prohibitin
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: PHB
Gene Symbols: PHB
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P35232
Gene ID (Entrez): 5245
Immunogen: Between 222 and 272
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: PHB
Antigen:
Prohibitin
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
PHB
Gene Symbols:
PHB
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P35232
Gene ID (Entrez):
5245
Immunogen:
Between 222 and 272
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
PHB
Antigen: ABC50
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: ABC27, ABC50, ATP-binding cassette 50 (TNF-alpha stimulated), ATP-binding cassette sub-family F member 1, TNF-alpha-stimulated ABC protein, TNFalpha-inducible ATP-binding protein
Gene Symbols: ABCF1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8NE71
Gene ID (Entrez): 23
Immunogen: Between 795 and 845
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: ABCF1
Antigen:
ABC50
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
ABC27, ABC50, ATP-binding cassette 50 (TNF-alpha stimulated), ATP-binding cassette sub-family F member 1, TNF-alpha-stimulated ABC protein, TNFalpha-inducible ATP-binding protein
Gene Symbols:
ABCF1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8NE71
Gene ID (Entrez):
23
Immunogen:
Between 795 and 845
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
ABCF1