7144513
JAK2 Polyclonal Antibody, Bethyl Laboratories
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
JAK2
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias
Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene Symbols
JAK2
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Applications
Immunohistochemistry
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human
Gene Accession No.
O60674
Gene ID (Entrez)
3717
Immunogen
Between 1082 and 1132
Primary or Secondary
Primary
Content And Storage
4° C
Gene
JAK2
Description
- The recommended shelf life for this product is 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Dog, Horse, Panda, Orangutan, Monkey, Gorilla, Chimpanzee, Northern white-cheeked gibbon, Naked m Janus Activating Kinase 2 (JAK2) is a non-rececptor tyrosine kinase involved in various processes such as cell growth, development, differentiation, and histone modifications
- In response to a varitety of cytokine or related factors (e.g., interferon, interleukins), JAKs are activated via phosphorylation at 2 adjacent tyrosine residues
- The activation of JAKs can lead to the phosphorylation of STAT (signal transducers and activatiors of transcription) proteins, which dimerize and translocate to the nucleus
- Once translocated to the nucleus, the STAT proteins can modify transcription of numerous genes, including interferon-stimulated genes
- JAK2 is required for the IFN gamma-receptor complex initiation and JAK1 functions as an amplifier
- Some studies have suggested that the role of JAK2 might be performed by Tyk2 and JAK3, if they were positioned correctly within the IFN gamma-receptor complex
- Mutations affecting this gene can cause Budd-Chiari syndrome, Polycythemia vera, Thrombocythemia 3, myelofibrosis, or Acute myelogenous leukemia.
Compare Similar Items
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Antigen: JAK2
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene Symbols: JAK2
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O60674
Gene ID (Entrez): 3717
Immunogen: Between 1082 and 1132
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: JAK2
Antigen:
JAK2
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Tyrosine-protein kinase JAK2; Janus kinase 2; JAK-2
Gene Symbols:
JAK2
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O60674
Gene ID (Entrez):
3717
Immunogen:
Between 1082 and 1132
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
JAK2
Antigen: HBO
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: Histone acetyltransferase MYST2; EC 2.3.1.48; MYST protein 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; Histone acetyltransferase binding to ORC1; MYST2; HBO1; HBOa
Gene Symbols: KAT7
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: O95251
Gene ID (Entrez): 11143
Immunogen: Between 125 and 175
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: KAT7
Antigen:
HBO
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
Histone acetyltransferase MYST2; EC 2.3.1.48; MYST protein 2; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; Histone acetyltransferase binding to ORC1; MYST2; HBO1; HBOa
Gene Symbols:
KAT7
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
O95251
Gene ID (Entrez):
11143
Immunogen:
Between 125 and 175
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
KAT7
Antigen: DDX27
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: DEAD (Asp-Glu-Ala-Asp) box polypeptide 27, DRS1, RHLP, Rrp3p, PP3241, HSPC259, dJ686N3.1
Gene Symbols: __
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q921N6, Q96GQ7
Gene ID (Entrez): 228889, 55661
Immunogen: Between 700 and 750
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: DDX27
Antigen:
DDX27
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27, DRS1, RHLP, Rrp3p, PP3241, HSPC259, dJ686N3.1
Gene Symbols:
__
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q921N6, Q96GQ7
Gene ID (Entrez):
228889, 55661
Immunogen:
Between 700 and 750
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
DDX27
Antigen: BCCIP
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias: TOK-1, TOK1, BCCIPalpha, BCCIPbeta, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, TOK-1alpha, TOK-1beta, cdk inhibitor p21 binding protein, p21- and CDK-associated protein 1, protein TOK-1
Gene Symbols: BCCIP
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Applications: Immunofluorescence, Immunohistochemistry
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9P287
Gene ID (Entrez): 56647
Immunogen: Between 300 and 350
Primary or Secondary: Primary
Content And Storage: 4° C
Gene: BCCIP
Antigen:
BCCIP
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
TBS with 0.1% BSA and 0.09% sodium azide
Gene Alias:
TOK-1, TOK1, BCCIPalpha, BCCIPbeta, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, TOK-1alpha, TOK-1beta, cdk inhibitor p21 binding protein, p21- and CDK-associated protein 1, protein TOK-1
Gene Symbols:
BCCIP
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Applications:
Immunofluorescence, Immunohistochemistry
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9P287
Gene ID (Entrez):
56647
Immunogen:
Between 300 and 350
Primary or Secondary:
Primary
Content And Storage:
4° C
Gene:
BCCIP