7144576

Vinculin Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Vinculin

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

RP11-178G16.3, CMD1W, MVCL

Gene Symbols

VCL

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P18206

Gene ID (Entrez)

7414

Immunogen

Between 1016 and 1066

Primary or Secondary

Primary

Content And Storage

4° C

Gene

VCL

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, Zebrafish, Chicken, Turkey, Bovine, Horse, Rabbit, Guinea pig_10141, Pig, Pand Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions
  • It functions as one of several interacting proteins involved in anchoring F-actin to the membrane
  • It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques
  • In the assembly of adhesion plaques, the beta subunit of integrin binds to talin
  • Talin binds to vinculin that interacts with alpha-actinin and possibly with itself
  • Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system
  • Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.

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Img

Fischer Scientific

7144576

Rabbit Polyclonal Antibody...


Antigen:
Vinculin

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
RP11-178G16.3, CMD1W, MVCL

Gene Symbols:
VCL

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P18206

Gene ID (Entrez):
7414

Immunogen:
Between 1016 and 1066

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
VCL

Img

Fischer Scientific

7144577

Rabbit Polyclonal Antibody...


Antigen:
RuvBL2

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
CGI-46, ECP51, RVB2, TIP48, TIP49B

Gene Symbols:
__

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q9WTM5, Q9Y230

Gene ID (Entrez):
10856, 20174

Immunogen:
Between 1 and 50

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
RUVBL2

Img

Fischer Scientific

7144577

Rabbit Polyclonal Antibody...


Antigen:
RuvBL2

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
CGI-46, ECP51, RVB2, TIP48, TIP49B

Gene Symbols:
__

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q9WTM5, Q9Y230

Gene ID (Entrez):
10856, 20174

Immunogen:
Between 1 and 50

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
RUVBL2

Img

Fischer Scientific

7144578

Rabbit Polyclonal Antibody...


Antigen:
EAF2

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
BM040, testosterone-regulated apoptosis inducer and tumor suppressor protein, TRAITS, U19

Gene Symbols:
EAF2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q96CJ1

Gene ID (Entrez):
55840

Immunogen:
Between 150 and 200

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
EAF2