7144593

JMY Polyclonal Antibody, Bethyl Laboratories

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

JMY

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias

FLJ37870, junction-mediating and regulatory protein, WAS protein homology region 2 domain containing 1-like 3, WHAMM2, WHDC1L3

Gene Symbols

JMY

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Applications

Immunohistochemistry

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q8N9B5

Gene ID (Entrez)

133746

Immunogen

Between 1 and 50

Primary or Secondary

Primary

Content And Storage

4° C

Gene

JMY

Description

  • The recommended shelf life for this product is 1 year from date of receipt
  • Based on 100% sequence identity, this antibody is predicted to react with Mouse, Bovine, Dog, Guinea pig_10141, Panda, Monkey, Gorilla, Chimpanzee, Northern white-c JMY acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions
  • In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300
  • Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage
  • In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments
  • Activates the Arp2/3 complex to induce branched actin filament networks
  • Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments
  • Contributes to cell motility by controlling actin dynamics
  • May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments
  • The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location.

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Fischer Scientific

7144593

Rabbit Polyclonal Antibody...


Antigen:
JMY

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
FLJ37870, junction-mediating and regulatory protein, WAS protein homology region 2 domain containing 1-like 3, WHAMM2, WHDC1L3

Gene Symbols:
JMY

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q8N9B5

Gene ID (Entrez):
133746

Immunogen:
Between 1 and 50

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
JMY

Img

Fischer Scientific

7144594

Rabbit Polyclonal Antibody...


Antigen:
HCA66

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
C17orf40, HCA66, U3 small nucleolar RNA-associated protein 6 homolog, hepatocellular carcinoma associated antigen 66, hepatocellular carcinoma-associated antigen 66, multiple hat domains protein

Gene Symbols:
UTP6

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9NYH9

Gene ID (Entrez):
55813

Immunogen:
Between 565 and 597

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
UTP6

Img

Fischer Scientific

7144594

Rabbit Polyclonal Antibody...


Antigen:
HCA66

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
C17orf40, HCA66, U3 small nucleolar RNA-associated protein 6 homolog, hepatocellular carcinoma associated antigen 66, hepatocellular carcinoma-associated antigen 66, multiple hat domains protein

Gene Symbols:
UTP6

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9NYH9

Gene ID (Entrez):
55813

Immunogen:
Between 565 and 597

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
UTP6

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Fischer Scientific

7144595

Rabbit Polyclonal Antibody...


Antigen:
MED13L

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
TBS with 0.1% BSA and 0.09% sodium azide

Gene Alias:
KIAA1025, PROSIT240, THRAP2, TRAP240L

Gene Symbols:
MED13L

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Applications:
Immunohistochemistry

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q71F56

Gene ID (Entrez):
23389

Immunogen:
Between 550 and 600

Primary or Secondary:
Primary

Content And Storage:
4° C

Gene:
MED13L