7161715

CD64 Mouse anti-Human, Brilliant Ultraviolet 737, Clone: 10.1, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

CD64

Applications

Flow Cytometry

Conjugate

Brilliant Ultraviolet 737

Regulatory Status

RUO

Formulation

Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype

IgG1 κ

Purification Method

Affinity Purified

Clone

10.1

Classification

Monoclonal

Host Species

Mouse

Target Species

Human

Immunogen

Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes

Primary or Secondary

Primary

Content And Storage

Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Description

  • The 10.1 monoclonal antibody specifically binds to CD64, a 72 kDa type I transmembrane glycoprotein that is a high affinity receptor for human IgG (FcγRI), especially the IgG1 and IgG3 subclasses
  • CD64 is expressed on monocytes, macrophages, dendritic cells, granulocytes activated with interferon-gamma and early myeloid lineage cells
  • CD64 associates with a signaling FcRγhomodimer to form the functional high affinity FcγRI complex
  • CD64 functions in both innate and adaptive immune responses and mediates endocytosis, phagocytosis, antigen presentation, antibody-dependent cellular toxicity, cytokine release and superoxide generation
  • Due to spectral differences between labeled cells and beads, using BD™ CompBeads can result in incorrect spillover values when used with BD Horizon BUV737 reagents
  • Therefore, the use of BD CompBeads or BD CompBeads Plus to determine spillover values for these reagents is not recommended
  • Different BUV737 reagents (e.g., CD4 vs
  • CD45) can have slightly different fluorescence spillover therefore, it may also be necessary to use clone specific compensation controls when using these reagents.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7161715

Mouse Monoclonal Antibody...


Antigen:
CD64

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 737

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
10.1

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Human Rheumatoid synovial fluid cells and fibronectin-purified monocytes

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

7161716

Mouse Monoclonal Antibody...


Antigen:
CD8

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 496

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
RPA-T8

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Baboon, Human, Rhesus Monkey

Immunogen:
Human CD8a

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

7161717

Mouse Monoclonal Antibody...


Antigen:
CD127

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 737

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
HIL-7R-M21

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Recombinant Human IL-7R

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

Img

Fischer Scientific

7161717

Mouse Monoclonal Antibody...


Antigen:
CD127

Applications:
Flow Cytometry

Conjugate:
Brilliant Ultraviolet 737

Regulatory Status:
RUO

Formulation:
Aqueous buffered solution containing ≤0.09% sodium azide.

Isotype:
IgG1 κ

Purification Method:
Affinity Purified

Clone:
HIL-7R-M21

Classification:
Monoclonal

Host Species:
Mouse

Target Species:
Human

Immunogen:
Recombinant Human IL-7R

Primary or Secondary:
Primary

Content And Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.