7162120
CD169 (Siglec-1) Monoclonal Antibody (SER-4), APC-eFluor™ 780, eBioscience™, Invitrogen™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
CD169 (Siglec-1)
Concentration
0.2 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.09% sodium azide, pH 7.2
Gene Alias
Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Gene Symbols
SIGLEC1
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
SIGLEC1
Clone
SER-4
Applications
Flow Cytometry
Conjugate
APC-eFluor 780
Host Species
Rat
Target Species
Mouse
Gene Accession No.
Q62230
Gene ID (Entrez)
20612
Isotype
IgG2a κ
Purification Method
Affinity chromatography
Product Type
Antibody
Description
- Description: The SER-4 monoclonal antibody reacts with mouse CD169, which is also known as Sialoadhesin and Siglec-1
- CD169 is a 185-kDa member of the Siglec family of adhesion and endocytic receptors that recognize sialylated glycans
- This receptor is expressed on a subset of macrophages that are found with high frequency in the spleen, liver, lymph node, and bone marrow
- CD169 can also be detected on monocytes in the bone marrow and periphery
- This receptor plays a role in cell-cell adhesion, as well as internalization of sialylated virus and bacteria
- This endocytic pathway allows CD169+ macrophages to present lipid antigens to iNKT cells, thereby leading to their activation
- Studies have also demonstrated that direct interaction of CD169 with regulatory T cells inhibits their proliferation
- The SER-4 antibody has been reported to have antagonist activity
- Applications Reported: This SER-4 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This SER-4 antibody has been tested by flow cytometric analysis of mouse bone marrow cells
- This may be used at less than or equal to 0.5 μg per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest
- The siglecs are a family of membrane bound lectins (of the immunoglobulin superfamily) that bind sialic acid and mediate cell-cell interactions
- Family members include sialoadhesin, CD22 and CD33
- Sialoadhesin is a macrophage-specific cell adhesion molecule that is expressed on activated macrophages in chronic inflammation and in tumours.
Compare Similar Items
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Antigen: CD169 (Siglec-1)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Gene Symbols: SIGLEC1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: SIGLEC1
Clone: SER-4
Applications: Flow Cytometry
Conjugate: APC-eFluor 780
Host Species: Rat
Target Species: Mouse
Gene Accession No.: Q62230
Gene ID (Entrez): 20612
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD169 (Siglec-1)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
Cd169, dJ1009E24.1, macrophage receptor, p210, pSn, SA, SER, sheep erythrocyte receptor, sialic acid binding Ig like lectin 1, sialic acid binding Ig-like lectin 1, sialoadhesin, Sialic acid-binding Ig-like lectin 1, sialic acid-binding immunoglobulin-like lectin 1, sialoadhesin, SIGLEC1, Siglec-1, SN
Gene Symbols:
SIGLEC1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
SIGLEC1
Clone:
SER-4
Applications:
Flow Cytometry
Conjugate:
APC-eFluor 780
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
Q62230
Gene ID (Entrez):
20612
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD172a (SIRP alpha)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Gene Symbols: SIRPA
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: SIRPA
Clone: P84
Applications: Flow Cytometry
Conjugate: Super Bright 436
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P97797
Gene ID (Entrez): 19261
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD172a (SIRP alpha)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
AI835480, Bit, brain Ig-like molecule with tyrosine-based activation motifs, Brain immunoglobulin like protein with tyrosine - based activation motifs, brain immunological-like with tyrosine-based motifs, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, CD172, CD172 alpha, CD172 antigen-like family member A, CD172A, Inhibitory receptor SHPS-1, macrophage fusion receptor, Macrophage membrane protein MFP150, MFR, mSIRP-alpha1, Myd1, MYD-1, myD-1 antigen, p84, Protein tyrosine phosphatase non-receptor type substrate 1 (SHP substrate 1), protein tyrosine phosphatase, non-receptor type substrate 1, Protein tyrosine phosphatase, non-receptor type substrate 1 (SHP substrate 1), Ptpns1, SHP substrate 1, SHP-1, SHPS1, SHPS-1, signal regulatory protein alpha, signal-regulatory protein alpha, signal-regulatory protein alpha-1, Signal-regulatory protein alpha-2, Signal-regulatory protein alpha-3, SIRP, Sirpa, SIRPalpha, Sirp-alpha-1, SIRPalpha2, Sirp-alpha-2, Sirp-alpha-3, swc3, swine workshop cluster 3 antigen, swine workshop cluster 3 antigen precursor, tyrosine phosphatase SHP substrate 1, tyrosine-protein phosphatase non-receptor type substrate 1
Gene Symbols:
SIRPA
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
SIRPA
Clone:
P84
Applications:
Flow Cytometry
Conjugate:
Super Bright 436
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P97797
Gene ID (Entrez):
19261
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD24
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias: CD24, CD24 antigen, CD24 antigen (small cell lung carcinoma cluster 4 antigen), CD24 molecule, CD24A, CD24a antigen, cluster of differentiation 24, FLJ22950, FLJ43543, heat stable antigen, heat-stable antigen, HSA, Ly-52, Lymphocyte antigen 52, M1/69-J11D heat stable antigen, MGC75043, Nectadrin, nectadrin heat stable antigen, R13-Ag, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen
Gene Symbols: Cd24
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Cd24
Clone: eBioSN3 (SN3 A5-2H10)
Applications: Flow Cytometry
Conjugate: Super Bright 436
Host Species: Mouse
Target Species: Human
Gene Accession No.: P25063
Gene ID (Entrez): 100133941
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD24
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
CD24, CD24 antigen, CD24 antigen (small cell lung carcinoma cluster 4 antigen), CD24 molecule, CD24A, CD24a antigen, cluster of differentiation 24, FLJ22950, FLJ43543, heat stable antigen, heat-stable antigen, HSA, Ly-52, Lymphocyte antigen 52, M1/69-J11D heat stable antigen, MGC75043, Nectadrin, nectadrin heat stable antigen, R13-Ag, Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen, X62 heat stable antigen
Gene Symbols:
Cd24
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Cd24
Clone:
eBioSN3 (SN3 A5-2H10)
Applications:
Flow Cytometry
Conjugate:
Super Bright 436
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P25063
Gene ID (Entrez):
100133941
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD25
Concentration: 0.5 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.09% sodium azide, pH 7.2
Gene Alias: ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR
Gene Symbols: IL2RA
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: IL2RA
Clone: PC61.5
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Rat
Target Species: Mouse
Gene Accession No.: P01590
Gene ID (Entrez): 16184
Isotype: IgG1 λ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD25
Concentration:
0.5 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.09% sodium azide, pH 7.2
Gene Alias:
ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
IL2RA
Clone:
PC61.5
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Rat
Target Species:
Mouse
Gene Accession No.:
P01590
Gene ID (Entrez):
16184
Isotype:
IgG1 λ
Purification Method:
Affinity chromatography
Product Type:
Antibody