7162592
CD25 Monoclonal Antibody (BC96), FITC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD25
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias
ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR
Gene Symbols
IL2RA
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
IL2RA
Clone
BC96
Applications
Flow Cytometry
Conjugate
FITC
Host Species
Mouse
Target Species
Human
Gene Accession No.
P01589
Gene ID (Entrez)
3559
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Description
- Description: The BC96 monoclonal antibody reacts with human CD25, the 55 kDa interleukin-2 receptor alpha chain (IL-2R alpha)
- CD25 is expressed by early progenitors of T and B lineage as well as by activated mature T and B lymphocytes
- By itself, CD25 binds IL-2 only with low affinity
- However, CD25 associates with CD122 (IL-2 receptor beta chain) and CD132 (common gamma chain) to form the high affinity IL-2 receptor
- CD25 plays a role in lymphocyte differentiating and activation/proliferation
- Applications Reported: This BC96 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This BC96 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells
- This may be used at 5 μL (0.25 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 488 nm; Emission: 520 nm; Laser: Blue Laser CD25 (IL2 receptor alpha chain/IL2RA) is a cytokine that plays a role in the proliferation of T and B lymphocytes
- The receptor of this cytokine (IL2RA) is a heterotrimeric protein complex with a gamma chain also shared by interleukin 4 (IL4) and interleukin 7 (IL7)
- IL2RA, IL2R beta chain (IL2RB), and the IL2R gamma chain (IL2RG), constitute the high-affinity IL2 receptor
- Homodimeric IL2RA chains result in low-affinity receptor, while homodimeric IL2RB chains produce a medium-affinity receptor
- The expression of IL2 in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene
- IL2 is primarily produced by mature T cells
- IL2 plays an important role as a growth factor, differentiation factor, and regulator of cell death
- IL-2 stimulates the proliferation of B cells, augments natural killer cell activity, and inhibits granulocyte macrophage colony formation
- The targeted disruption of a similar gene in mice leads to μgcerative colitis-like disease, which suggests a role in the immune response to antigenic stimuli
- Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.
Compare Similar Items
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Antigen: CD25
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias: ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR
Gene Symbols: IL2RA
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: IL2RA
Clone: BC96
Applications: Flow Cytometry
Conjugate: FITC
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01589
Gene ID (Entrez): 3559
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD25
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
ADA, ADA1, Adenosine aminohydrolase, adenosine deaminase, CD25, CD25 antigen, cytokine receptor, IDDM10, IL 2 RA, IL 2 receptor, IL 2R, IL 2R subunit alpha, IL2 RA, IL2 RA antibody, IL2 receptor, il-2 receptor alpha, IL-2 Receptor alpha chain, IL-2 receptor alpha subunit, IL2 receptor subunit alpha, IL-2 receptor subunit alpha, IL2R, IL-2R alpha, IL-2R alpha chain, IL2R subunit alpha, IL-2R subunit alpha, Il2ra, IL-2RA, IL-2-RA, IL2-RA, Il2ra antibody, IL2RAC, IMD41, interleukin 2 receptor, interleukin 2 receptor alpha chain, interleukin 2 receptor subunit alpha, interleukin 2 receptor, alpha, interleukin 2 receptor, alpha chain, interleukin-2 receptor alpha, interleukin-2 receptor alpha chain, interleukin-2 receptor alpha subunit, interleukin-2 receptor beta chain, Interleukin2 receptor subunit alpha, interleukin-2 receptor subunit alpha, Ly-43, p55, p55 chain, sIL 2R, soluble IL 2 receptor, TAC antigen, TCGFR
Gene Symbols:
IL2RA
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
IL2RA
Clone:
BC96
Applications:
Flow Cytometry
Conjugate:
FITC
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01589
Gene ID (Entrez):
3559
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD33
Concentration: __
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: __
Gene Alias: CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Gene Symbols: CD33
Primary or Secondary: Primary
Content And Storage: -20°C or -80°C if preferred
Gene: CD33
Clone: __
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20138
Gene ID (Entrez): 945
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
CD33
Concentration:
__
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
__
Gene Alias:
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Gene Symbols:
CD33
Primary or Secondary:
Primary
Content And Storage:
-20°C or -80°C if preferred
Gene:
CD33
Clone:
__
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20138
Gene ID (Entrez):
945
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody
Antigen: CD33
Concentration: __
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: __
Gene Alias: CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Gene Symbols: CD33
Primary or Secondary: Primary
Content And Storage: -20°C or -80°C if preferred
Gene: CD33
Clone: __
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P20138
Gene ID (Entrez): 945
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
CD33
Concentration:
__
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
__
Gene Alias:
CD33, CD33 antigen, CD33 antigen (gp67), CD33 molecule, CD33 molecule transcript, FLJ00391, gp67, Myeloid cell surface antigen CD33, p67, sialic acid binding Ig-like lectin 3, sialic acid-binding Ig-like lectin 3, SIGLEC3, Siglec-3
Gene Symbols:
CD33
Primary or Secondary:
Primary
Content And Storage:
-20°C or -80°C if preferred
Gene:
CD33
Clone:
__
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P20138
Gene ID (Entrez):
945
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody
Antigen: CD36
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias: adipocyte membrane protein, BDPLT10, Cd36, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule, CD36 molecule (thrombospondin receptor), CD36 protein, CHDS7, cluster determinant 36, collagen type I receptor thrombospondin receptor, collagen type I receptor, thrombospondin receptor, FAT, FAT/CD36, fatty acid translocase, fatty acid translocase/CD36, fatty acid transport protein, glycoprotein IIIb, GP3B, GP4, GPIIIB, GPIV, I79_011940, Leukocyte differentiation antigen CD36, PAS IV, PAS4, PAS-4, PAS-4 protein, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, platelet glycoprotein IV, Scarb3, scavenger receptor class B, member 3, SR-B3, Thrombospondin receptor
Gene Symbols: CD36
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: CD36
Clone: eBioNL07 (NL07)
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Host Species: Mouse
Target Species: Human
Gene Accession No.: P16671
Gene ID (Entrez): 948
Isotype: IgM
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD36
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide, pH 7.2
Gene Alias:
adipocyte membrane protein, BDPLT10, Cd36, CD36 antigen, CD36 antigen (collagen type I receptor, thrombospondin receptor), CD36 molecule, CD36 molecule (thrombospondin receptor), CD36 protein, CHDS7, cluster determinant 36, collagen type I receptor thrombospondin receptor, collagen type I receptor, thrombospondin receptor, FAT, FAT/CD36, fatty acid translocase, fatty acid translocase/CD36, fatty acid transport protein, glycoprotein IIIb, GP3B, GP4, GPIIIB, GPIV, I79_011940, Leukocyte differentiation antigen CD36, PAS IV, PAS4, PAS-4, PAS-4 protein, PASIV, Platelet collagen receptor, Platelet glycoprotein 4, platelet glycoprotein IV, Scarb3, scavenger receptor class B, member 3, SR-B3, Thrombospondin receptor
Gene Symbols:
CD36
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
CD36
Clone:
eBioNL07 (NL07)
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P16671
Gene ID (Entrez):
948
Isotype:
IgM
Purification Method:
Affinity chromatography
Product Type:
Antibody