Thermo Scientific™ LanthaScreen™ Tb-anti-Histone H3K27me3 Antibody

Description

• Description The LanthaScreen™ Tb-anti-Histone H3K27me3 antibody is a key component of the BacMam Histone H3K27me3 Cellullar Assay (A14159) When this terbium (Tb)- labeled antibody is paired with baculovirus-mediated (BacMam) expression of a Histone H3-GFP fusion protein, the TR-FRET readout enables sensitive detection of H3 lysine 27 trimethylation The resulting high-throughput screening (HTS) compatible assay can be used to identify inhibitors of methyltransferases and demethylases acting on lysine 27 of histone H3 For research use only Not for human or animal therapeutic or diagnostic use LanthaScreen™ Tb-anti-Histone H3K27me3 Antibody Allows Users to: Identify more relevant inhibitors since the methyl transferases and demethylases are in their natural protein complexes Conserve precious cell samples with the miniaturizable homogenous assay format Improve data quality with the advantages of TR-FRET