7188406

Phospho-STAT1 (Ser727) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Phospho-STAT1 (Ser727)

Applications

Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P42224

Gene ID (Entrez)

6772

Immunogen

This STAT1 phospho Ser727 antibody was raised against a synthetic peptide containing phospho-serine 727 of human STAT1.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias

2010005J02Rik; AA408197; BOS_1917; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; Signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription 1-like; signal transducer and activator of transcription-1; STAT; STAT1; STAT91; transcription factor ISGF-3; Transcription factor ISGF-3 components p91/p84

Gene Symbols

STAT1

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

STAT1

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Description

  • STAT1 (signal transducers and activators of transcription 1) is a member of the STAT family of transcription factors
  • STAT1 can be activated by interferon-alpha, interferon-gamma, EGF, PDGF and IL6
  • STAT1 is known to regulate several genes which are involved in cell growth, apoptosis, immune responses, and lipid metabolism
  • Further, STAT1 plays an important role in mediating cell viability in response to different cell stimuli and pathogen exposure
  • The STAT1 gene is located on chromosome 2
  • STAT1 is activated to regulate gene expression in response to extracellular signaling polypeptides including cytokines, interferons, and growth factors
  • After phosphorylation by JAK tyrosine kinases, STAT1 enters the nucleus to regulate transcription of many different genes
  • Among the seven STATs types, STAT1, STAT3, STAT5a, and STAT5b have a wide activation profile
  • STAT1 is activated by many different ligands including IFN family (IFN-Alpha, IFN-Beta, IFN-gamma and IL-10), gp130 family (IL-6, IL-11, LIF, CNTF, and G-CSF), and receptor tyrosine kinases (EGF, PDGF, and CSF-1)
  • Two alternatively spliced transcript variants encoding distinct isoforms of STAT1 have been described.

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Fischer Scientific

7188406

Rabbit Polyclonal Antibody...


Antigen:
Phospho-STAT1 (Ser727)

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P42224

Gene ID (Entrez):
6772

Immunogen:
This STAT1 phospho Ser727 antibody was raised against a synthetic peptide containing phospho-serine 727 of human STAT1.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
2010005J02Rik; AA408197; BOS_1917; CANDF7; DD6G4-4; DKFZp686B04100; IMD31A; IMD31B; IMD31C; ISGF-3; LOW QUALITY PROTEIN: signal transducer and activator of transcription 1-alpha/beta; OTTHUMP00000165046; OTTHUMP00000205845; Signal transducer and activator of transcription 1; signal transducer and activator of transcription 1, 91kD; signal transducer and activator of transcription 1, 91kDa; Signal transducer and activator of transcription 1-alpha/beta; signal transducer and activator of transcription 1-like; signal transducer and activator of transcription-1; STAT; STAT1; STAT91; transcription factor ISGF-3; Transcription factor ISGF-3 components p91/p84

Gene Symbols:
STAT1

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
STAT1

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7188410

Rabbit Polyclonal Antibody...


Antigen:
PHF8

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9UPP1

Gene ID (Entrez):
23133

Immunogen:
This PHF8 antibody was raised against a synthetic peptide derived from human PHF8.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
9830141C09Rik; Histone lysine demethylase PHF8; JHDM1F; jumonji C domain-containing histone demethylase 1F; Kiaa1111; mKIAA1111; MRXSSD; PHD finger protein 8; PHF8; ZNF422

Gene Symbols:
PHF8

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
PHF8

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7188412

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K4me3

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 trimethyl Lys4 antibody was raised against a peptide including trimethyl-lysine 4 of histone H3.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
B0035.7; BUR5; CELE_T10C6.12; CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Dmel\CG31613; Dmel_CG31613; F07B7.10; F07B7.3; F08G2.2; F17E9.13; F35H10.1; F45F2.4; F54E12.5; F55G1.10; H02I12.7; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3B.1; H3 histone, family 3C; H3 K4; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3c10; H3C11; H3C12; H3C2; H3C3; H3C4;

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

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Mouse Recombinant Monoclonal Antibo...


Antigen:
BMI-1

Applications:
ChIP sequencing (ChIP-seq), Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P25916, P35226

Gene ID (Entrez):
12151, 648

Immunogen:
This antibody was raised against full length human BMI1-BMI1 polycomb ring finger oncogene.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.07% sodium azide; pH 7.5

Gene Alias:
AW546694; B lymphoma Mo-MLV insertion region 1; B lymphoma Mo-MLV insertion region 1 homolog; Bmi1; Bmi-1; BMI1 polycomb ring finger oncogene; BMI1 polycomb ring finger proto-oncogene; BMI1 proto-oncogene, polycomb ring finger; FLVI2/BMI1; flvi-2/bmi-1; murine leukemia viral (bmi-1) oncogene homolog; PCGF4; Pcgf4 antibody; Polycomb complex protein BMI-1; polycomb group protein Bmi1; polycomb group ring finger 4; Polycomb group RING finger protein 4; RING finger protein 51; RNF51; RP11-573G6.1

Gene Symbols:
BMI1

Isotype:
IgG2a

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
BMI1