7188424
CDK8 Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CDK8
Applications
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P49336, Q8R3L8
Gene ID (Entrez)
1024, 264064
Immunogen
This antibody was raised against a peptide within the C-terminal region of human CDk8.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Cdk8
Concentration
Lot-Specific
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
Cdk8; CDK8 protein kinase; Cell division protein kinase 8; cyclin dependent kinase 8; Cyclin-dependent kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; Protein kinase K35; RGD1560888; wu:fk95h11
Gene Symbols
Cdk8
Isotype
IgG
Purification Method
Antigen affinity chromatography
Product Type
Antibody
Related Products
Description
- A family of proteins designated as cdks are critical regulators of cell cycle progression
- The prototype member of this family, p34/Cdc 2, and a related protein Cdk 2, function late in the cycle while Cdk 4 and Cdk 6 are critically involved in G1 to S progression
- The p54/Cdk 8 interacts exclusively with Cyclin C
- The Cdk 8 Cyclin C complex activates the kinase
- Because of analogy with yeast Cdk 8, it has been proposed that the human Cdk 8 Cyclin C may interact with RNA polymerase, thus influencing the transcription mechanism(s) that lead to cell division.
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Antigen: CDK8
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P49336, Q8R3L8
Gene ID (Entrez): 1024, 264064
Immunogen: This antibody was raised against a peptide within the C-terminal region of human CDk8.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Cdk8
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: Cdk8; CDK8 protein kinase; Cell division protein kinase 8; cyclin dependent kinase 8; Cyclin-dependent kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; Protein kinase K35; RGD1560888; wu:fk95h11
Gene Symbols: Cdk8
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
CDK8
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P49336, Q8R3L8
Gene ID (Entrez):
1024, 264064
Immunogen:
This antibody was raised against a peptide within the C-terminal region of human CDk8.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Cdk8
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
Cdk8; CDK8 protein kinase; Cell division protein kinase 8; cyclin dependent kinase 8; Cyclin-dependent kinase 8; K35; Mediator complex subunit CDK8; Mediator of RNA polymerase II transcription subunit CDK8; MGC126074; MGC126075; Protein kinase K35; RGD1560888; wu:fk95h11
Gene Symbols:
Cdk8
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Antigen: Histone H4K5ac/K8ac
Applications: ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Multi-species, Mouse, Rat
Gene Accession No.: P62804
Gene ID (Entrez): 502913, 64627, 679983
Immunogen: This antibody was raised against a full-length human H4 protein containing acetyl k5 and k8 (H4k5ack8ac).
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: HIST1H4B
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: __
Gene Symbols: HIST1H4A, HIST1H4B, HIST2H4A
Isotype: IgG1
Purification Method: Protein A
Product Type: Antibody
Antigen:
Histone H4K5ac/K8ac
Applications:
ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Multi-species, Mouse, Rat
Gene Accession No.:
P62804
Gene ID (Entrez):
502913, 64627, 679983
Immunogen:
This antibody was raised against a full-length human H4 protein containing acetyl k5 and k8 (H4k5ack8ac).
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
HIST1H4B
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
__
Gene Symbols:
HIST1H4A, HIST1H4B, HIST2H4A
Isotype:
IgG1
Purification Method:
Protein A
Product Type:
Antibody
Antigen: Histone H4K5ac/K8ac
Applications: ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Multi-species, Mouse, Rat
Gene Accession No.: P62804
Gene ID (Entrez): 502913, 64627, 679983
Immunogen: This antibody was raised against a full-length human H4 protein containing acetyl k5 and k8 (H4k5ack8ac).
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: HIST1H4B
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: __
Gene Symbols: HIST1H4A, HIST1H4B, HIST2H4A
Isotype: IgG1
Purification Method: Protein A
Product Type: Antibody
Antigen:
Histone H4K5ac/K8ac
Applications:
ChIP sequencing (ChIP-seq), Dot Blot, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Multi-species, Mouse, Rat
Gene Accession No.:
P62804
Gene ID (Entrez):
502913, 64627, 679983
Immunogen:
This antibody was raised against a full-length human H4 protein containing acetyl k5 and k8 (H4k5ack8ac).
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
HIST1H4B
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
__
Gene Symbols:
HIST1H4A, HIST1H4B, HIST2H4A
Isotype:
IgG1
Purification Method:
Protein A
Product Type:
Antibody
Antigen: PARP-1 C-terminal
Applications: ChIP Assay, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P09874
Gene ID (Entrez): 142
Immunogen: This PARP-1 C-terminal antibody was raised against a His-Tagged fusion protein corresponding to the C-terminal half of human PARP-1 was used to generate this PARP-1 antibody.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Parp1
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: 5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein p
Gene Symbols: Parp1
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
PARP-1 C-terminal
Applications:
ChIP Assay, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P09874
Gene ID (Entrez):
142
Immunogen:
This PARP-1 C-terminal antibody was raised against a His-Tagged fusion protein corresponding to the C-terminal half of human PARP-1 was used to generate this PARP-1 antibody.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Parp1
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
5830444G22Rik; ADP-ribosyltransferase (NAD+; ADP-ribosyltransferase (NAD+) poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) 1; ADP-ribosyltransferase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase NAD(+); Adprp; ADPRT; ADPRT 1; ADPRT1; AI893648; ARTD1; BOS_15645; C80510; DNA ADP-ribosyltransferase PARP1; I79_014850; msPARP; NAD(+) ADP-ribosyltransferase 1; NAD(+) pADPRT-1; pADPRT-1; Parp; PARP1; PARP-1; poly (ADP-ribose) polymerase 1; poly (ADP-ribose) polymerase family, member 1; poly (ADP-ribose) polymerase); Poly [ADP-ribose] polymerase 1; poly ADP-ribose polymerase; poly(ADP-ribose) polymerase; poly(ADP-ribose) polymerase 1; poly(ADP-ribose) polymerase PARP-1; poly(ADP-ribose) synthetase; poly(ADP-ribosyl)transferase; Poly[ADP-ribose] synthase 1; poly[ADP-ribose] synthetase 1; PPOL; Protein p
Gene Symbols:
Parp1
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody