7188591

Histone H3ac (pan-acetyl) Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H3ac (pan-acetyl)

Applications

ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Immunogen

This Histone H3 acetyl antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of histone H3.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

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Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Fischer Scientific

7188591

Rabbit Polyclonal Antibody...


Antigen:
Histone H3ac (pan-acetyl)

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This Histone H3 acetyl antibody was raised against a peptide including acetyl-lysines contained in the N-terminal tail of histone H3.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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Fischer Scientific

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Rabbit Polyclonal Antibody...


Antigen:
POLR2B

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This antibody was raised against a peptide within the N-terminal region of human POLR2B.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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7188594

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Antigen:
Histone H3K4me3

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Yeast

Immunogen:
This Histone H3 trimethyl Lys4 antibody was raised against a peptide including trimethyl-lysine 4 of histone H3.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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7188595

Rat Monoclonal Antibody...


Antigen:
SMARCA4

Applications:
Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rat

Target Species:
Human, Monkey, Mouse

Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 213-295 of human SMARCA4.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG2a

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles