7188665

ACTL6B Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

ACTL6B

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

O94805

Gene ID (Entrez)

51412

Immunogen

This antibody was raised against a peptide within the N-terminal region of human ACTL6B.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Actl6b

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

53 kDa BRG1-associated factor B; actin like 6B; actin-like 6; actin-like 6B; Actin-like protein 6B; actin-like protein 6B {ECO:0000250; Actin-related protein Baf53b; Actl6; ACTL6B; actl6b {ECO:0000250; Arpna; ArpNalpha; ArpN-alpha; BAF53B; BRG1-associated factor 53B; hArpN alpha; UniProtKB:O94805}

Gene Symbols

Actl6b

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Related Products

Img

Fischer Scientific

7188378

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188378

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188643

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188643

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188437

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188437

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188781

Rabbit Polyclonal Antibody...

Img

Fischer Scientific

7188506

Rabbit Polyclonal Antibody...

Description

  • Belongs to the chromatin remodeling brain-specific BAF (bBAF) complex, as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion
  • Belongs to the neuron-specific chromatin remodeling complex (nBAF complex) and is required for postmitotic neural development and dendritic outgrowth
  • During neural development a switch from a stem/progenitor to a post-mitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state
  • The transition from proliferating neural stem/progenitor cells to post-mitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes
  • As neural progenitors exit mitosis and differentiate into neurons, npBAF complexes which contain ACTL6A/BAF53A and PHF10/BAF45A, are exchanged for homologous alternative ACTL6B/BAF53B and DPF1/BAF45B or DPF3/BAF45C subunits in neuron-specific complexes (nBAF)
  • The npBAF complex is essential for the self-renewal/proliferative capacity of the multipotent neural stem cells
  • The nBAF complex along with CREST plays a role regulating the activity of genes essential for dendrite growth
  • ACTL6B/BAF53B is not essential for assembly of the nBAF complex but is required for targeting the complex and CREST to the promoter of genes essential for dendritic growth.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7188665

Rabbit Polyclonal Antibody...


Antigen:
ACTL6B

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
O94805

Gene ID (Entrez):
51412

Immunogen:
This antibody was raised against a peptide within the N-terminal region of human ACTL6B.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Actl6b

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
53 kDa BRG1-associated factor B; actin like 6B; actin-like 6; actin-like 6B; Actin-like protein 6B; actin-like protein 6B {ECO:0000250; Actin-related protein Baf53b; Actl6; ACTL6B; actl6b {ECO:0000250; Arpna; ArpNalpha; ArpN-alpha; BAF53B; BRG1-associated factor 53B; hArpN alpha; UniProtKB:O94805}

Gene Symbols:
Actl6b

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7188666

Rabbit Polyclonal Antibody...


Antigen:
GCN5

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q92830

Gene ID (Entrez):
2648

Immunogen:
This GCN5 antibody was raised against a peptide within the N-terminal region of human GCN5.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
KAT2A

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
1110051E14Rik; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; GCN5L2; general control of amino acid synthesis 5-like 2; General control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; Histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2A; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97

Gene Symbols:
KAT2A

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Img

Fischer Scientific

7188666

Rabbit Polyclonal Antibody...


Antigen:
GCN5

Applications:
Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q92830

Gene ID (Entrez):
2648

Immunogen:
This GCN5 antibody was raised against a peptide within the N-terminal region of human GCN5.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
KAT2A

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
1110051E14Rik; AW212720; GCN5; GCN5 (general control of amino-acid synthesis, yeast, homolog)-like 2; GCN5 general control of amino acid synthesis-like 2; GCN5L2; general control of amino acid synthesis 5-like 2; General control of amino acid synthesis protein 5-like 2; general control of amino acid synthesis, yeast homolog-like 2; General control of amino acid synthesis, yeast, homolog-like 2; general control of amino acid synthesis-like 2; hGCN5; Histone acetyltransferase GCN5; Histone acetyltransferase KAT2A; Histone succinyltransferase KAT2A; hsGCN5; K(lysine) acetyltransferase 2A; KAT2A; KATA2; Lysine acetyltransferase 2A; MmGCN5; PCAF-b; PCAF-B/GCN5; STAF97

Gene Symbols:
KAT2A

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Img

Fischer Scientific

7188669

Rabbit Polyclonal Antibody...


Antigen:
EuHMT1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9H9B1

Gene ID (Entrez):
79813

Immunogen:
This EuHMT1 antibody was raised against a peptide derived from the N-terminal region of human EuHMT1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
EHMT1

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
bA188C12.1; EHMT1; euchromatic histone lysine methyltransferase 1; Euchromatic histone-lysine N-methyltransferase 1; EUHMTASE1; Eu-HMTase1; FP13812; G9a-like protein 1; GLP; GLP1; H3-K9-HMTase 5; Histone H3-K9 methyltransferase 5; Histone-lysine N-methyltransferase EHMT1; histone-lysine N-methyltransferase, H3 lysine-9 specific 5; KIAA1876; KMT1D; Lysine N-methyltransferase 1D

Gene Symbols:
EHMT1

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody