7188745
Nanog Recombinant Mouse Monoclonal Antibody, AbFlex™, Active Motif™
Mouse Recombinant Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
Nanog
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Mouse
Gene Accession No.
Q80Z64
Gene ID (Entrez)
71950
Immunogen
This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
NANOG
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias
2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Gene Symbols
NANOG
Isotype
IgG2a
Purification Method
Protein A
Product Type
Antibody
Related Products
Description
- NANOG (Nanog homeobox) is a divergent homeodomain protein that directs pluripotency and differentiation of undifferentiated embryonic stem cells
- NANOG mRNA is present in pluripotent mouse and human cell lines, and absent from differentiated cells
- Human NANOG protein shares 52% overall amino acid identity with the mouse protein, and 85% identity in the homeodomain
- Human NANOG maps to gene locus 12p13.31, while the mouse NANOG maps to gene loci 6 F2
- Murine embryonic NANOG expression is detected in the inner cell mass of the blastocyst
- Research studies have shown that high levels of human NANOG expression in the undifferentiated N-Tera embryonal carcinoma cell line
- Further, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal
- The role of NANOG in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of several degenerative diseases
- Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing POU5F1 (also known as Oct-4), another germline-specific transcription factor, and the transcription factors Sox2, Klf4 and Lin28 along with c-Myc in mouse fibroblasts
- Experiments have demonstrated that iPS cells could be generated using expression plasmids expressing NANOG, Sox2, KlfF4 and c-Myc, eliminating the need for virus introduction, thereby addressing a safety concern for potential use of iPS cells in regenerative medicine
- When overexpressed, NANOG promotes cells to enter into S phase and proliferation
- Diseases associated with dysfunction in the NANOG protein include tetracarcinoma and germ cell/embryonal cancer.
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Antigen: Nanog
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: Q80Z64
Gene ID (Entrez): 71950
Immunogen: This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NANOG
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: 2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Gene Symbols: NANOG
Isotype: IgG2a
Purification Method: Protein A
Product Type: Antibody
Antigen:
Nanog
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
Q80Z64
Gene ID (Entrez):
71950
Immunogen:
This antibody was raised against a peptide comprising amino acids 2-25 of mouse Nanog.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NANOG
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 32mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
2410002E02Rik; early embryo specific expression NK family; Early embryo specific expression NK-type homeobox protein; Ecat4; Enk; ES cell-associated protein 4; FLJ12581; HGNC:20857; hNanog; Homeobox protein NANOG; Homeobox transcription factor Nanog; homeobox transcription factor Nanog-delta 48; homeodomain transcription factor Nanog; NANOG; Nanog homeobox; Nanog homeodomain transcription factor
Gene Symbols:
NANOG
Isotype:
IgG2a
Purification Method:
Protein A
Product Type:
Antibody
Antigen: Myc-Tag
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01106
Gene ID (Entrez): 4609
Immunogen: This antibody was raised against a peptide corresponding to amino acids 410-419 of human c-Myc (EQkLISEEDL).
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MYC
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: 46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols: MYC
Isotype: IgG2a
Purification Method: Protein A
Product Type: Antibody
Antigen:
Myc-Tag
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01106
Gene ID (Entrez):
4609
Immunogen:
This antibody was raised against a peptide corresponding to amino acids 410-419 of human c-Myc (EQkLISEEDL).
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MYC
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols:
MYC
Isotype:
IgG2a
Purification Method:
Protein A
Product Type:
Antibody
Antigen: Myc-Tag
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P01106
Gene ID (Entrez): 4609
Immunogen: This antibody was raised against a peptide corresponding to amino acids 410-419 of human c-Myc (EQkLISEEDL).
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MYC
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias: 46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols: MYC
Isotype: IgG2a
Purification Method: Protein A
Product Type: Antibody
Antigen:
Myc-Tag
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P01106
Gene ID (Entrez):
4609
Immunogen:
This antibody was raised against a peptide corresponding to amino acids 410-419 of human c-Myc (EQkLISEEDL).
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MYC
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5
Gene Alias:
46-0603; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; MRTL; MYC; Myc protein; Myc proto-oncogene protein; Myc Tag; MYCC; myc-related translation/localization regulatory factor; Proto-oncogene c-Myc; R95025; R950-25; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols:
MYC
Isotype:
IgG2a
Purification Method:
Protein A
Product Type:
Antibody
Antigen: c-Fos
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P01100
Gene ID (Entrez): 2353
Immunogen: This antibody was raised against a peptide within human c-Fos.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: FOS
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: activator protein 1; AP-1; BOS_11003; cellular oncogene c-fos; Cellular oncogene fos; cFos; c-fos; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ osteosarcoma oncogene; Fos; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 7; G0S7; I79_009428; LOC100338345; murine FBJ osteosarcoma viral (v-fos) oncogene homolog; p55; proto-oncogene cFOS; Proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Symbols: FOS
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Antigen:
c-Fos
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P01100
Gene ID (Entrez):
2353
Immunogen:
This antibody was raised against a peptide within human c-Fos.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
FOS
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
activator protein 1; AP-1; BOS_11003; cellular oncogene c-fos; Cellular oncogene fos; cFos; c-fos; c-fos oncogene; c-fos protooncogene protein; D12Rfj1; FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS); FBJ murine osteosarcoma viral oncogene homolog; FBJ osteosarcoma oncogene; Fos; Fos proto-oncogene, AP-1 trancription factor subunit; Fos proto-oncogene, AP-1 transcription factor subunit; G0/G1 switch regulatory protein 7; G0S7; I79_009428; LOC100338345; murine FBJ osteosarcoma viral (v-fos) oncogene homolog; p55; proto-oncogene cFOS; Proto-oncogene c-Fos; proto-oncogene protein c-fos; v-fos FBJ murine osteosarcoma viral oncogene homolog
Gene Symbols:
FOS
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody