7188758
SREBP-1 Monoclonal Antibody (IgG-2A4), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
SREBP-1
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Gene Symbols
SREBF1
Isotype
IgG
Purification Method
Protein G
Product Type
Antibody
Clone
IgG-2A4
Applications
ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
P36956
Gene ID (Entrez)
6720
Immunogen
This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
SREBF1
Related Products
Description
- Sterol regulatory element-binding proteins (SREBPs) are transcription factors that are members of the basic helix-loop-helix leucine zipper family of DNA binding proteins
- Three isoforms have been identified in mammalian tissues that vary in structure, regulation, and function
- SREBP-1a and SREBP-1c (originally cloned as ADD1) are protein products of alternative promoter usage of the SREBP-1 gene
- The third isoform is transcribed from a different gene, SREBP-2
- SREBPs are present as 120 kDa inactive precursors in the endoplasmic reticulum (ER) membrane
- Upon activation, the SREBP protein is translocated to the Golgi and proteolytic cleavage occurs resulting in a mature transcriptionally active 60-78 kDa fragment
- In liver and adipose tissues, SREBPs have a significant influence on lipid and cholesterol accumulation by inducing the transcription of genes involved in these processes
- While SREBP-1 is thought to be more important in regulating the expression of genes involved in triglyceride synthesis and accumulation, SREBP-2 has been more closely linked to those involved in cholesterol synthesis and accumulation.
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Antigen: SREBP-1
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Gene Symbols: SREBF1
Isotype: IgG
Purification Method: Protein G
Product Type: Antibody
Clone: IgG-2A4
Applications: ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: P36956
Gene ID (Entrez): 6720
Immunogen: This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SREBF1
Antigen:
SREBP-1
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
ADD1; ADD-1; Adipocyte determination- and differentiation-dependent factor 1; BHLHD1; Class D basic helix-loop-helix protein 1; D630008H06; I79_010155; nt-SREBP1; Processed sterol regulatory element-binding protein 1; SREBF1; SREBP1; SREBP-1; SREBP1a; SREBP-1a; SREBP1c; SREBP-1c; sterol regulatory element binding protein 1; sterol regulatory element binding protein-1; sterol regulatory element binding transcription factor 1; sterol regulatory element binding-protein 1; Sterol regulatory element-binding protein 1; Sterol regulatory element-binding transcription factor 1
Gene Symbols:
SREBF1
Isotype:
IgG
Purification Method:
Protein G
Product Type:
Antibody
Clone:
IgG-2A4
Applications:
ChIP Assay, Gel Shift, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P36956
Gene ID (Entrez):
6720
Immunogen:
This SREBP-1 antibody was raised against a recombinant protein corresponding to amino acids 301-407 of human SREBP-1.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SREBF1
Antigen: AIB3
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris HCl with 1% BSA, 105mM NaCl, 30% glycerol, 70mM glycine and 0.035% sodium azide; pH 8
Gene Alias: Activating signal cointegrator 2; activating signal cointegrator-2; AIB3; Amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ASC2; ASC-2; Cancer-amplified transcriptional coactivator ASC-2; KIAA0181; mKIAA0181; NCOA6; Ncoa7; NRC; NRC RAP250; Nuclear receptor coactivator 6; Nuclear receptor coactivator RAP250; nuclear receptor-activating protein 250; Nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor interacting protein,PRIP; Peroxisome proliferator-activated receptor-interacting protein; PPAR interacting protein PRIP; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; Thyroid hormone receptor-binding protein; TRBP
Gene Symbols: NCOA6
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q14686, Q9JL19
Gene ID (Entrez): 23054, 56406
Immunogen: This AIB3 antibody was raised against a recombinant protein corresponding to amino acids 22-146 of mouse AIB3.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NCOA6
Antigen:
AIB3
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris HCl with 1% BSA, 105mM NaCl, 30% glycerol, 70mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
Activating signal cointegrator 2; activating signal cointegrator-2; AIB3; Amplified in breast cancer protein 3; amplified in breast cancer-3 protein; ASC2; ASC-2; Cancer-amplified transcriptional coactivator ASC-2; KIAA0181; mKIAA0181; NCOA6; Ncoa7; NRC; NRC RAP250; Nuclear receptor coactivator 6; Nuclear receptor coactivator RAP250; nuclear receptor-activating protein 250; Nuclear receptor-activating protein, 250 kDa; peroxisome proliferator-activated receptor interacting protein; peroxisome proliferator-activated receptor interacting protein,PRIP; Peroxisome proliferator-activated receptor-interacting protein; PPAR interacting protein PRIP; PPAR-interacting protein; PRIP; RAP250; thyroid hormone receptor binding protein; Thyroid hormone receptor-binding protein; TRBP
Gene Symbols:
NCOA6
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q14686, Q9JL19
Gene ID (Entrez):
23054, 56406
Immunogen:
This AIB3 antibody was raised against a recombinant protein corresponding to amino acids 22-146 of mouse AIB3.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NCOA6
Antigen: Ubn1
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; Ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
Gene Symbols: UBN1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9NPG3
Gene ID (Entrez): 29855
Immunogen: This Ubinuclein antibody was raised against a recombinant protein corresponding to amino acids 1-345 of human Ubn1.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: UBN1
Antigen:
Ubn1
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; Ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
Gene Symbols:
UBN1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9NPG3
Gene ID (Entrez):
29855
Immunogen:
This Ubinuclein antibody was raised against a recombinant protein corresponding to amino acids 1-345 of human Ubn1.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
UBN1
Antigen: Ubn1
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; Ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
Gene Symbols: UBN1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9NPG3
Gene ID (Entrez): 29855
Immunogen: This Ubinuclein antibody was raised against a recombinant protein corresponding to amino acids 1-345 of human Ubn1.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: UBN1
Antigen:
Ubn1
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
1110029L11Rik; 2610108L02Rik; AA673476; AW124741; HIRA-binding protein; Protein VT4; ubinuclein 1; Ubinuclein-1; Ubiquitously expressed nuclear protein; Ubn1; VT; VT4
Gene Symbols:
UBN1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9NPG3
Gene ID (Entrez):
29855
Immunogen:
This Ubinuclein antibody was raised against a recombinant protein corresponding to amino acids 1-345 of human Ubn1.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
UBN1