7188769
MLL / HRX Monoclonal Antibody (N4.4), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
MLL / HRX
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX
Gene Symbols
KMT2A
Isotype
IgG1
Purification Method
Protein G
Product Type
Antibody
Clone
N4.4
Applications
ChIP Assay, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human, Mouse
Gene Accession No.
P55200, Q03164
Gene ID (Entrez)
214162, 4297
Immunogen
This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 161-356 of mouse MLL.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
KMT2A
Related Products
Description
- KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
- It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
- In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
- KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
- It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
- Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.
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Antigen: MLL / HRX
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX
Gene Symbols: KMT2A
Isotype: IgG1
Purification Method: Protein G
Product Type: Antibody
Clone: N4.4
Applications: ChIP Assay, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: P55200, Q03164
Gene ID (Entrez): 214162, 4297
Immunogen: This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 161-356 of mouse MLL.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: KMT2A
Antigen:
MLL / HRX
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX
Gene Symbols:
KMT2A
Isotype:
IgG1
Purification Method:
Protein G
Product Type:
Antibody
Clone:
N4.4
Applications:
ChIP Assay, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
P55200, Q03164
Gene ID (Entrez):
214162, 4297
Immunogen:
This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 161-356 of mouse MLL.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
KMT2A
Antigen: Histone H4
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: BcDNA:RH52884; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; H4r; HHF1; HHF2; His4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4
Gene Symbols: H4-16, H4C1, H4C14, H4C2, H4C5, H4C9
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: ChIP Assay, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P62805
Gene ID (Entrez): 121504, 8294, 8359, 8366, 8367, 8370
Immunogen: This Histone H4 antibody was raised against a peptide corresponding to amino acids 43- 54 of human histone H4.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: H4C1
Antigen:
Histone H4
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
BcDNA:RH52884; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; H4r; HHF1; HHF2; His4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4
Gene Symbols:
H4-16, H4C1, H4C14, H4C2, H4C5, H4C9
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
ChIP Assay, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P62805
Gene ID (Entrez):
121504, 8294, 8359, 8366, 8367, 8370
Immunogen:
This Histone H4 antibody was raised against a peptide corresponding to amino acids 43- 54 of human histone H4.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
H4C1
Antigen: Histone H4
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: BcDNA:RH52884; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; H4r; HHF1; HHF2; His4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4
Gene Symbols: H4-16, H4C1, H4C14, H4C2, H4C5, H4C9
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: ChIP Assay, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P62805
Gene ID (Entrez): 121504, 8294, 8359, 8366, 8367, 8370
Immunogen: This Histone H4 antibody was raised against a peptide corresponding to amino acids 43- 54 of human histone H4.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: H4C1
Antigen:
Histone H4
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
BcDNA:RH52884; CG31611; CG3379; CG3379 gene product from transcript CG3379-RA; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; FBtr0082962; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4c11; H4C12; H4C13; H4C14; H4C15; H4C2; H4C3; H4C4; H4C5; H4c6; H4C8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4M; H4r; HHF1; HHF2; His4; His4:CG31611; His4:CG33869; His4:CG33871; His4:CG33873; His4:CG33875; His4:CG33877; His4:CG33879; His4:CG33881; His4:CG33883; His4:CG33885; His4:CG33887; His4
Gene Symbols:
H4-16, H4C1, H4C14, H4C2, H4C5, H4C9
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
ChIP Assay, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P62805
Gene ID (Entrez):
121504, 8294, 8359, 8366, 8367, 8370
Immunogen:
This Histone H4 antibody was raised against a peptide corresponding to amino acids 43- 54 of human histone H4.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
H4C1
Antigen: LIN28A
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; lin28; lin-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; Lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein lin-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; Testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1
Gene Symbols: LIN28A
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: Q8K3Y3, Q9H9Z2
Gene ID (Entrez): 79727, 83557
Immunogen: This LIN28A antibody was raised against a peptide derived from the C-terminal region of human LIN28A.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: LIN28A
Antigen:
LIN28A
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
AL024421; CSDD1; ENSMUSG00000070700; FLJ12457; Gm10299; lin28; lin-28; lin-28 homolog A; lin-28 homolog A (C. elegans); Lin28a; Lin-28A; Protein lin-28 homolog A; RGD1566408; RNA-binding protein lin-28; sb:cb650; si:ch211-232d9.4; similar to RNA-binding protein LIN-28; testis expressed gene 17; Testis-expressed protein 17; Tex17; ZCCHC1; zgc:55584; Zinc finger CCHC domain-containing protein 1; zinc finger, CCHC domain containing 1
Gene Symbols:
LIN28A
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
Q8K3Y3, Q9H9Z2
Gene ID (Entrez):
79727, 83557
Immunogen:
This LIN28A antibody was raised against a peptide derived from the C-terminal region of human LIN28A.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
LIN28A