7188773

Cas9 Monoclonal Antibody (7A9-3A3), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

Cas9

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Gene Symbols

CASP9

Isotype

IgG1 κ

Purification Method

Protein G

Product Type

Antibody

Clone

7A9-3A3

Applications

Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P55211

Gene ID (Entrez)

842

Immunogen

This antibody was raised against a recombinant protein within the N-terminal region ofStreptococcus pyogeneCas9. This antibody should recognize Cas9 and dCas9 based on the antigen design.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

CASP9

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Description

  • Cas9 is a RNA-guided DNA endonuclease enzyme associated with the CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) adaptive immunity system in bacteria and genetic engineering
  • Staphylococcus aureus derived Cas9 has a number of properties that make it advantageous for genome editing, including its small size, high efficiency, nickase activity, and apparent specificity
  • SaCas9 principally recognizes an NNGRRT protospacer adjacent motif (PAM) and cleaves target DNA at rates comparable to SpCas9 (Cas9 derived from S
  • pyogenes) with an ideal spacer lengths of 24 to 20 nucleotides
  • In comparison to SpCas9, SaCas9 is smaller (1368 AA versus 1053 AA) and generates indels at a comparable rate when directed against target DNA with the mutually permissive NGGRRT PAM
  • This makes it the preferred enzyme for all-in-one delivery of Cas9 and multiple gRNA expression cassettes with Adeno-associated vectors.

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Fischer Scientific

7188773

Mouse Monoclonal Antibody...


Antigen:
Cas9

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
APAF3; APAF-3; apoptotic protease activating factor 3; Apoptotic protease Mch-6; Apoptotic protease-activating factor 3; cas9; CASP 9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; Caspase9; Caspase-9; Caspase-9 precursor; Caspase-9 subunit p10; Caspase-9 subunit p35; CASPASE-9c; CRISPR-Cas9; CTD; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56; RNCASP9; RP11-265F14.3

Gene Symbols:
CASP9

Isotype:
IgG1 κ

Purification Method:
Protein G

Product Type:
Antibody

Clone:
7A9-3A3

Applications:
Immunocytochemistry, Immunofluorescence, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P55211

Gene ID (Entrez):
842

Immunogen:
This antibody was raised against a recombinant protein within the N-terminal region ofStreptococcus pyogeneCas9. This antibody should recognize Cas9 and dCas9 based on the antigen design.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
CASP9

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7188774

Mouse Monoclonal Antibody...


Antigen:
MAD1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AI173502; AW550425; hMAD1; HsMAD1; Mad1; MAD1 mitotic arrest deficient 1-like 1; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); Mad1l1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; MXD1; PIG9; Tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181

Gene Symbols:
MAD1L1

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Clone:
9B10

Applications:
Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q9WTX8, Q9Y6D9

Gene ID (Entrez):
17120, 8379

Immunogen:
This MAD1 antibody was raised against a peptide corresponding to amino acids 331-718 of mouse MAD1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MAD1L1

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7188774

Mouse Monoclonal Antibody...


Antigen:
MAD1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AI173502; AW550425; hMAD1; HsMAD1; Mad1; MAD1 mitotic arrest deficient 1-like 1; MAD1 mitotic arrest deficient like 1; MAD1 mitotic arrest deficient-like 1; MAD1 mitotic arrest deficient-like 1 (yeast); Mad1l1; MAD1-like protein 1; mitotic arrest deficient 1-like 1; Mitotic arrest deficient 1-like protein 1; Mitotic checkpoint MAD1 protein homolog; Mitotic spindle assembly checkpoint protein MAD1; mitotic-arrest deficient 1, yeast, homolog-like 1; MXD1; PIG9; Tax-binding protein 181; TP53I9; tumor protein p53 inducible protein 9; TXBP181

Gene Symbols:
MAD1L1

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Clone:
9B10

Applications:
Immunocytochemistry, Immunofluorescence

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
Q9WTX8, Q9Y6D9

Gene ID (Entrez):
17120, 8379

Immunogen:
This MAD1 antibody was raised against a peptide corresponding to amino acids 331-718 of mouse MAD1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MAD1L1

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7188775

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K9me2

Concentration:
__

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
__

Gene Alias:
CG31613; CG31613 gene product from transcript CG31613-RA; CG31613-PA; CG33803; CG33806; CG33809; CG33812; CG33815; CG33818; CG33821; CG33824; CG33827; CG33830; CG33833; CG33836; CG33839; CG33842; CG33845; CG33848; CG33851; CG33854; CG33857; CG33860; CG33863; CG33866; Di histone H3/c; dimethyl H3; di-methyl H3; Dimethyl Histone H3; di-methyl histone H3; Di-Methyl-H3 K9; Di-Methyl-H3 Lys9; Di-Methyl-Histone H3 K9; Di-Methyl-Histone H3 Lys9; Dmel\CG31613; Dmel_CG31613; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K9me2; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; h3.2a; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3b; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Clone:
__

Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 dimethyl Lys9 antibody was raised against a peptide including dimethyl-lysine 9 of histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A