7188791
CtIP Monoclonal Antibody (14-1), Active Motif™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CtIP
Concentration
1 mg/mL
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Human
Gene Accession No.
Q99708
Gene ID (Entrez)
5932
Immunogen
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Rbbp8
Clone
14-1
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias
9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog
Gene Symbols
Rbbp8
Isotype
IgG1
Purification Method
Protein A
Product Type
Antibody
Related Products
Description
- CtIP, a 125 kD protein, was originally found interacting with a transcription repressor, CtBP, through the PLDLS motif (CtBP-Interacting Protein) thus suggested a role in transcription
- Studies have shown that CtIP also interacts with BRCA1 protein through the c-terminus BRCT domains also suggested that CtIP is a potential tumor suppressor
- This CtIP-BRCA1 interaction can be disrupted by DNA damaging agents including UV or gamma-irradiation
- Li et al (Nature 406, 210 - 215 (2000)) have shown that ATM phosphorylates CtIP at serine residues 664 and 745, and mutation of these sites abrogates the dissociation of BRCA1 from CtIP, resulting in persistent repression of BRCA1-dependent induction of GADD45 upon ionizing radiation.
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Antigen: CtIP
Concentration: 1 mg/mL
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q99708
Gene ID (Entrez): 5932
Immunogen: This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Rbbp8
Clone: 14-1
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog
Gene Symbols: Rbbp8
Isotype: IgG1
Purification Method: Protein A
Product Type: Antibody
Antigen:
CtIP
Concentration:
1 mg/mL
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q99708
Gene ID (Entrez):
5932
Immunogen:
This CtIP antibody was raised against a recombinant protein corresponding to amino acid residues 620-897 of human CtIP.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Rbbp8
Clone:
14-1
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
9930104E21Rik; COM1; CtBP-interacting protein; Ctip; DNA endonuclease RBBP8; JWDS; RB binding protein 8, endonuclease; Rbbp8; RBBP-8; retinoblastoma binding protein 8; Retinoblastoma-binding protein 8; Retinoblastoma-interacting protein and myosin-like; RGD1308872; RIM; SAE2; SCKL2; Sporulation in the absence of SPO11 protein 2 homolog
Gene Symbols:
Rbbp8
Isotype:
IgG1
Purification Method:
Protein A
Product Type:
Antibody
Antigen: RNA pol II
Concentration: 1 mg/mL
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human
Gene Accession No.: P24928
Gene ID (Entrez): 5430
Immunogen: This antibody was raised against a synthetic peptide containing the CTD of human RNA Polymerase II.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: POLR2A
Clone: 1F4B6
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols: POLR2A
Isotype: IgG2a
Purification Method: Protein G
Product Type: Antibody
Antigen:
RNA pol II
Concentration:
1 mg/mL
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P24928
Gene ID (Entrez):
5430
Immunogen:
This antibody was raised against a synthetic peptide containing the CTD of human RNA Polymerase II.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
POLR2A
Clone:
1F4B6
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
220kDa; BOS_18773; DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit; DNA-directed RNA polymerase II subunit A; DNA-directed RNA polymerase II subunit RPB1; DNA-directed RNA polymerase III largest subunit; EC 2.7.7.6; hRPB220; hsRPB1; MGC75453; Pol II S2p; POLR2; POLR2A; POLRA; Polymerase (RNA II (DNA directed), large polypeptide; polymerase (RNA) II (DNA directed) polypeptide A; polymerase (RNA) II (DNA directed) polypeptide A (220kD); polymerase (RNA) II (DNA directed) polypeptide A, 220kDa; polymerase (RNA) II subunit A; POLYMERASE II; RNA; RNA POL2; RNA polymerase II 1; RNA polymerase II subunit A; RNA polymerase II subunit B1; RNA-directed RNA polymerase II subunit RPB1; RP02; Rpb1; RPB220; RPBh1; Rpii215; RpIILS; RPO2; RPO21; Rpo2-1; RPOL2; SUA8
Gene Symbols:
POLR2A
Isotype:
IgG2a
Purification Method:
Protein G
Product Type:
Antibody
Antigen: Histone H4K31me1
Concentration: Conc. Not Determined
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: __
Clone: __
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: __
Gene Symbols: __
Isotype: IgG
Purification Method: __
Product Type: Antibody
Antigen:
Histone H4K31me1
Concentration:
Conc. Not Determined
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
This Histone H4 monomethyl Lys31 antibody was raised against a peptide containing monomethyl Lys31 of human histone H4.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
__
Clone:
__
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
__
Gene Symbols:
__
Isotype:
IgG
Purification Method:
__
Product Type:
Antibody
Antigen: p53
Concentration: Lot-Specific
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P04637
Gene ID (Entrez): 7157
Immunogen: This antibody was raised against recombinant human p53 protein.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Tp53
Clone: __
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.5
Gene Alias: 53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Gene Symbols: Tp53
Isotype: IgG
Purification Method: Protein G
Product Type: Antibody
Antigen:
p53
Concentration:
Lot-Specific
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P04637
Gene ID (Entrez):
7157
Immunogen:
This antibody was raised against recombinant human p53 protein.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Tp53
Clone:
__
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.5
Gene Alias:
53BP1; Antigen NY-CO-13; bbl; BCC7; bfy; bhy; BOS_18908; Cellular tumor antigen p53; Cys 51 Stop; EGK_08142; FLJ92943; HGNC11998; I79_002739; LFS1; Li-Fraumeni syndrome; m53BP1; murine p53-binding protein; mutant p53; mutant tumor protein 53; OTTMUSP00000006194; p44; P53; p53 cellular tumor antigen; p53 tumor suppressor; p53 tumor suppressor phosphoprotein; p53-binding protein 1; p53BP1; Phosphoprotein p53; tp53; tp53.L; TP53-binding protein 1; Tp53bp1; transformation related protein 53; transformation related protein 53 binding protein 1; transformation related protein 53 binding-protein 1; transformation-related protein 53; Trp248; Trp53; Trp53bp1; tumor protein 53; tumor protein p53; tumor protein p53 (Li-Fraumeni syndrome); tumor protein p53 L homeolog; Tumor suppressor p53; tumor suppressor p53-binding protein 1; tumor suppressor protein p53; tumor supressor p53; Tumour Protein p53; XELAEV_180196761mg; Xp53; Xrel3
Gene Symbols:
Tp53
Isotype:
IgG
Purification Method:
Protein G
Product Type:
Antibody