7188816

Ring1B Monoclonal Antibody (3-3), Active Motif™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Ring1B

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; BOS_16138; DING; DinG protein; E3 ubiquitin-protein ligase RING2; fa19h05; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; Protein DinG; RING 1B; RING 2; RING finger protein 1B; RING finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; RNF2; wu:fa19h05; wz4556; wz4566

Gene Symbols

RNF2

Isotype

IgG2b

Purification Method

Protein G

Product Type

Antibody

Concentration

1 mg/mL

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Monkey, Mouse

Gene Accession No.

Q99496, Q9CQJ4

Gene ID (Entrez)

19821, 6045

Immunogen

This Ring1B antibody was raised against the recombinant full-length mouse protein.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

RNF2

Description

  • RNF2 (E3 ubiquitin-protein ligase RING2) is a ligase that mediates monoubiquitination of Lys-119 of histone H2A (H2AK119Ub)
  • Therefore, it plays a central role in histone code and gene regulation
  • The ligase activity is enhanced by BMI1/PCGF4
  • H2AK119Ub gives a specific tag for epigeneti transcriptional repression and participates in X chromosome inactivation of female mammals
  • RNF2 may be involved in the initiation of both imprinted and random X inactivation
  • RNF2 is also an essential component of a Polycomb group (PcG) multiprotein PRC1-like complex
  • This complex class is required to maintain the transcriptionally repressive state of many genes including Hox genes throughout development
  • The PcG PRC1 complex acts via chromatin remodeling and modification of histones and rendering chromatin heritably changed in its expressibility.

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Fischer Scientific

7188816

Mouse Monoclonal Antibody...


Antigen:
Ring1B

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
AI326319; AI450156; AU019207; BAP 1; BAP1; BAP-1; BOS_16138; DING; DinG protein; E3 ubiquitin-protein ligase RING2; fa19h05; GS1-120K12.1; HIP2-interacting protein 3; HIPI 3; HIPI3; Huntingtin-interacting protein 2-interacting protein 3; OTTHUMP00000060668; Protein DinG; RING 1B; RING 2; RING finger protein 1B; RING finger protein 2; RING finger protein BAP-1; RING1B; RING2; RING-type E3 ubiquitin transferase RING2; RNF 2; RNF2; wu:fa19h05; wz4556; wz4566

Gene Symbols:
RNF2

Isotype:
IgG2b

Purification Method:
Protein G

Product Type:
Antibody

Concentration:
1 mg/mL

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Monkey, Mouse

Gene Accession No.:
Q99496, Q9CQJ4

Gene ID (Entrez):
19821, 6045

Immunogen:
This Ring1B antibody was raised against the recombinant full-length mouse protein.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
RNF2

Img

Fischer Scientific

7188817

Mouse Monoclonal Antibody...


Antigen:
Histone H4K20me3

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.035% sodium azide; pH 7.5

Gene Alias:
CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4C11; H4c12; H4C13; H4C14; H4C15; H4C2; H4C3; H4c4; H4C5; H4C6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; Hist2h4a; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone c

Gene Symbols:
H4-16, H4C1, H4C14, H4C2, H4C5, H4C9

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Concentration:
1 mg/mL

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P62805, P62806

Gene ID (Entrez):
121504, 319158, 326619, 326620, 8294, 8359, 8366, 8367, 8370, 97122

Immunogen:
This Histone H4 trimethyl Lys20 antibody (mAb) was raised against a peptide containing trimethyl Lys20 of Histone H4.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H4C1

Img

Fischer Scientific

7188817

Mouse Monoclonal Antibody...


Antigen:
Histone H4K20me3

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.035% sodium azide; pH 7.5

Gene Alias:
CELE_T10C6.11; F07B7.11; F07B7.4; F45F2.12; FO108; H4; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4 K20; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4C11; H4c12; H4C13; H4C14; H4C15; H4C2; H4C3; H4c4; H4C5; H4C6; H4C8; H4c9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4K20; H4Lys20me3; H4M; his-20; his-22; his-4; his-52; his-54; his-8; HIST1H4; HIST1H4A; Hist1h4b; HIST1H4C; HIST1H4D; HIST1H4E; HIST1H4F; HIST1H4H; HIST1H4I; HIST1H4J; HIST1H4K; HIST1H4L; Hist1h4m; HIST2H4; Hist2h4a; HIST2H4B; Hist4h4; histone 1, H4a; histone 1, H4b; histone 1, H4e; histone 1, H4i; histone 2, H4; histone 2, H4a; Histone 4; Histone 4 family, member M; histone 4, H4; histone cluster 1, H4a; histone cluster 1, H4b; histone cluster 1, H4e; histone cluster 1, H4i; histone c

Gene Symbols:
H4-16, H4C1, H4C14, H4C2, H4C5, H4C9

Isotype:
IgG

Purification Method:
Protein G

Product Type:
Antibody

Concentration:
1 mg/mL

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse

Gene Accession No.:
P62805, P62806

Gene ID (Entrez):
121504, 319158, 326619, 326620, 8294, 8359, 8366, 8367, 8370, 97122

Immunogen:
This Histone H4 trimethyl Lys20 antibody (mAb) was raised against a peptide containing trimethyl Lys20 of Histone H4.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H4C1

Img

Fischer Scientific

7188818

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K23me1

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
__

Gene Symbols:
H3C15, H3C2

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

Concentration:
Conc. Not Determined

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q71DI3

Gene ID (Entrez):
126961, 333932, 8358

Immunogen:
This Histone H3 monomethyl Lys23 antibody was raised against a peptide containing monomethyl Lys23 of human histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3C15