7188895
HP1 alpha Polyclonal Antibody, Active Motif™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
HP1 alpha
Applications
Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Mouse
Gene Accession No.
P45973, Q61686
Gene ID (Entrez)
12419, 23468
Immunogen
This HP1 alpha antibody was raised against a recombinant protein corresponding to full-length recombinant mouse HP1 alpha.
Primary or Secondary
Primary
Product Type
Antibody
Concentration
Conc. Not Determined
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias
2610029O15Rik; Antigen p25; BOS_4984; C75991; CBX5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; Heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)
Gene Symbols
Cbx5
Isotype
IgG
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Cbx5
Description
- Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
- It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
- High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
- Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
- In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.
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Antigen: HP1 alpha
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P45973, Q61686
Gene ID (Entrez): 12419, 23468
Immunogen: This HP1 alpha antibody was raised against a recombinant protein corresponding to full-length recombinant mouse HP1 alpha.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Conc. Not Determined
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias: 2610029O15Rik; Antigen p25; BOS_4984; C75991; CBX5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; Heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)
Gene Symbols: Cbx5
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Cbx5
Antigen:
HP1 alpha
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P45973, Q61686
Gene ID (Entrez):
12419, 23468
Immunogen:
This HP1 alpha antibody was raised against a recombinant protein corresponding to full-length recombinant mouse HP1 alpha.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Conc. Not Determined
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH
Gene Alias:
2610029O15Rik; Antigen p25; BOS_4984; C75991; CBX5; Cbx5 antibody; chromobox 5; chromobox homolog 5; chromobox homolog 5 (HP1 alpha homolog, Drosophila); Chromobox protein homolog 5; chromobox-like protein 5; epididymis luminal protein 25; HEL25; heterochromatin protein 1 alpha; Heterochromatin protein 1 homolog alpha; heterochromatin protein 1-alpha; HGNC:1555; HP1; HP1 alpha; HP-1 alpha antibody; HP1 alpha homolog; Hp1a; Hp1alpha; HP1-ALPHA; HP1Hs alpha; HP1Hs-alpha; mHP1(alpha)
Gene Symbols:
Cbx5
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Cbx5
Antigen: JMJD3 / KDM6B
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: O15054, Q5NCY0
Gene ID (Entrez): 216850, 23135
Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346
Gene Symbols: KDM6B
Isotype: IgG1
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: KDM6B
Antigen:
JMJD3 / KDM6B
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
O15054, Q5NCY0
Gene ID (Entrez):
216850, 23135
Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346
Gene Symbols:
KDM6B
Isotype:
IgG1
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
KDM6B
Antigen: JMJD3 / KDM6B
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human, Mouse
Gene Accession No.: O15054, Q5NCY0
Gene ID (Entrez): 216850, 23135
Immunogen: This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346
Gene Symbols: KDM6B
Isotype: IgG1
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: KDM6B
Antigen:
JMJD3 / KDM6B
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human, Mouse
Gene Accession No.:
O15054, Q5NCY0
Gene ID (Entrez):
216850, 23135
Immunogen:
This antibody was raised against a recombinant protein corresponding to amino acids 1028-1684 of human JMJD3 / kDM6B.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
1700064E03Rik; BC038313; JmjC domain-containing protein 3; Jmjd3; jumonji domain containing 3; jumonji domain containing 3, histone lysine demethylase; jumonji domain-containing 3; Jumonji domain-containing protein 3; KDM1 lysine (K)-specific demethylase 6B; Kdm6b; Kiaa0346; lysine (K)-specific demethylase 6B; Lysine demethylase 6B; Lysine-specific demethylase 6B; mKIAA0346
Gene Symbols:
KDM6B
Isotype:
IgG1
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
KDM6B
Antigen: MLL / HRX
Applications: ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Mouse
Gene Accession No.: P55200, Q03164
Gene ID (Entrez): 214162, 4297
Immunogen: This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.
Primary or Secondary: Primary
Product Type: Antibody
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX
Gene Symbols: KMT2A
Isotype: IgG
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: KMT2A
Antigen:
MLL / HRX
Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Immunocytochemistry, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P55200, Q03164
Gene ID (Entrez):
214162, 4297
Immunogen:
This MLL / HRX antibody was raised against a recombinant protein corresponding to amino acids 2829-2883 of human MLL.
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; Histone-lysine N-methyltransferase 2A; HRX; HTRX; HTRX1; KMT2A; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; Lysine N-methyltransferase 2A; mixed lineage leukemia 1; MLL; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); Myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; Trithorax-like protein; TRX1; WDSTS; Zinc finger protein HRX
Gene Symbols:
KMT2A
Isotype:
IgG
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
KMT2A