7188934

MBD2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MBD2

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

Q9UBB5

Gene ID (Entrez)

8932

Immunogen

This MBD2 antibody was raised against a synthetic peptide corresponding to human MBD2.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Mbd2

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias

Demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; Methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41

Gene Symbols

Mbd2

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Description

  • Heterochromatin protein-1 (HP1) is a methyl-lysine binding protein localized at heterochromatin sites, where it mediates gene silencing
  • It has been shown that mammalian methyltransferases that selectively methylate histone H3 on lysine-9 generate a binding site for HP1 proteins, a family of heterochromatic adaptor molecules implicated in both gene silencing and supranucleosomal chromatin structure
  • High-affinity in vitro recognition of a methylated histone H3 peptide by HP1 requires a functional chromodomain
  • Thus, the HP1 chromodomain is a specific interaction motif for the methyl epitope on lysine-9 of histone H3
  • In vivo, heterochromatin association of HP1 proteins is lost in Suv39h double-null primary mouse fibroblasts but is restored after reintroduction of a catalytically active SUV39H1 HMTase.

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Fischer Scientific

7188934

Rabbit Polyclonal Antibody...


Antigen:
MBD2

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9UBB5

Gene ID (Entrez):
8932

Immunogen:
This MBD2 antibody was raised against a synthetic peptide corresponding to human MBD2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Mbd2

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
Demethylase; DKFZp586O0821; DMTase; MBD2; MBD2a; methyl-CpG binding domain protein 2; Methyl-CpG-binding domain protein 2; Methyl-CpG-binding protein MBD2; NY-CO-41

Gene Symbols:
Mbd2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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7188936

Mouse Monoclonal Antibody...


Antigen:
TNF

Applications:
ELISA

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P01375

Gene ID (Entrez):
7124

Immunogen:
This antibody was raised against Human TNF.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Tnf

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor

Gene Symbols:
Tnf

Isotype:
IgG2a

Purification Method:
Protein A

Product Type:
Antibody

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7188940

Rabbit Polyclonal Antibody...


Antigen:
Histone H3K23ac

Applications:
ChIP Assay, Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 acetyl Lys23 antibody was raised against a peptide including acetyl-lysine 23 of histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
Acetyl H3; Acetyl Histone H3; Acetyl-H3 K23; Acetyl-H3 Lys23; Acetyl-Histone H3 K23; Acetyl-Histone H3 Lys23; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K23ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3B; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3b; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3C10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3F3B; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3K23; Hist1; HIST1H3A; Hist1h3b; Hist1h3c; Hist1h3d; HIST1H3E; Hist1h3f; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1; Hist2h3c2;

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody

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7188941

Rabbit Polyclonal Antibody...


Antigen:
Sox2

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Mouse

Gene Accession No.:
P48432

Gene ID (Entrez):
20674

Immunogen:
This Sox2 antibody was raised against a peptide corresponding to amino acids amino acids 111-140 mouse Sox2.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
SOX2

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Gene Alias:
ANOP3; cb236; lcc; MCOPS3; RGD1565646; sex determining region Y-box 2; sox2; Sox-2; soxp; SRY (sex determining region Y)-box 2; SRY box 2; SRY-box 2; SRY-box containing gene 2; SRY-related HMG-box gene 2; transcription factor SOX2; Transcription factor SOX-2; wu:fb83g04; wu:fc14d07; ysb; zgc:65860; zgc:77389

Gene Symbols:
SOX2

Isotype:
IgG

Purification Method:
__

Product Type:
Antibody