7188950

Histone H3K56me2 Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H3K56me2

Applications

Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Immunogen

This Histone H3 dimethyl Lys56 antibody was raised against a peptide including dimethyl-lysine 56 of human histone H3.

Primary or Secondary

Primary

Product Type

Antibody

Concentration

Conc. Not Determined

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype

IgG

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Antigen:
Histone H3K56me2

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This Histone H3 dimethyl Lys56 antibody was raised against a peptide including dimethyl-lysine 56 of human histone H3.

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
Conc. Not Determined

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
whole serum with 30% glycerol and 0.035% sodium azide; pH

Isotype:
IgG

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

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Applications:
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Conjugate:
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Host Species:
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Target Species:
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Immunogen:
This antibody was raised against a peptide corresponding to amino acids 21-39 of human Histone H3.3.

Primary or Secondary:
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Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
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Regulatory Status:
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Formulation:
140mM HEPES, 35mM sodium acetate with 30% glycerol, 70mM NaCl and 0.035% sodium azide; pH 7.5

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Conjugate:
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Primary or Secondary:
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Antigen:
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Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
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Host Species:
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Target Species:
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Immunogen:
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Primary or Secondary:
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Product Type:
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Concentration:
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