7188982

RYBP Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

RYBP

Applications

Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse

Gene Accession No.

Q8CCI5, Q8N488

Gene ID (Entrez)

23429, 56353

Immunogen

This antibody was raised against a peptide within the C-terminal region of human RYBP.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Rybp

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias

2410018J24Rik; AAP1; APAP-1; Apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; RYBP; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Gene Symbols

Rybp

Isotype

IgG

Purification Method

Antigen affinity chromatography

Product Type

Antibody

Description

  • RYBP involves component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development
  • PcG PRC1-like complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility
  • Component of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females
  • May stimulate ubiquitination of histone H2A 'Lys-119' by recruiting the complex to target sites
  • Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes
  • May also regulate the ubiquitin-mediated proteasomal degradation of other proteins like FANK1 to regulate apoptosis
  • May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1
  • May bind to DNA
  • May play a role in the repression of tumor growth and metastasis in breast cancer by down-regulating SRRM3.

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Fischer Scientific

7188982

Rabbit Polyclonal Antibody...


Antigen:
RYBP

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse

Gene Accession No.:
Q8CCI5, Q8N488

Gene ID (Entrez):
23429, 56353

Immunogen:
This antibody was raised against a peptide within the C-terminal region of human RYBP.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Rybp

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
2410018J24Rik; AAP1; APAP-1; Apoptin-associating protein 1; Death effector domain-associated factor; DEDAF; DED-associated factor; RING1 and YY1 binding protein; RING1 and YY1-binding protein; ring1 interactor RYBP; RYBP; YEAF1; YY1 and E4TF1 associated factor 1; YY1 and E4TF1-associated factor 1

Gene Symbols:
Rybp

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7188987

Mouse Monoclonal Antibody...


Antigen:
Histone H3K27ac

Applications:
ChIP Assay, ChIP sequencing (ChIP-seq), Dot Blot, Immunocytochemistry, Immunofluorescence, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P68431, P84243, Q6NXT2, Q71DI3

Gene ID (Entrez):
126961, 3020, 3021, 333932, 440093, 8350, 8357, 8358, 8968

Immunogen:
This Histone H3 acetyl Lys27 antibody was raised against a synthetic peptide including acetyl-lysine 27 of human histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
H3-3A

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Gene Alias:
Acetyl H3; Acetyl Histone H3; Acetyl-H3 K27; Acetyl-H3 Lys27; Acetyl-Histone H3 K27; Acetyl-Histone H3 Lys27; H3; H3 histone; H3 histone family, member A; H3 histone family, member I; H3 histone family, member K; H3 histone family, member L; H3 histone family, member M; H3 histone, family 2; H3 histone, family 3A; H3 histone, family 3B; H3 histone, family 3B (H3.3B); H3 histone, family 3C; H3 K27ac; H3.1-221; H3.1-291; H3.1-I; H3.2; H3.2-221; H3.2-614; H3.2-615; H3.2-616; H3.3A; H3.3b; H3.5; H3/A; H3/b; H3/d; H3/f; H3/i; H3/j; H3/k; H3/l; H3/M; H3/n; H3/o; H3-143; H3-291; H3-3A; H3-3B; H3-53; H3-614; H3a; H3b; H3-B; H3c1; H3c10; H3c11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3c8; H3f; H3-F; H3F1K; H3F2; H3F3; H3F3A; H3f3b; H3F3C; H3FA; H3FB; H3FC HIST1H3C; H3FD; H3FF; H3FH; H3FI; H3FJ; H3FK; H3FL; H3FM; H3FN; H3g; H3h; H3i; H3k27; H3Lys27ac; Hist1; Hist1h3a; HIST1H3B; Hist1h3c; HIST1H3D; Hist1h3e; HIST1H3F; HIST1H3G; HIST1H3H; Hist1h3i; HIST1H3J; HIST2H3A; Hist2h3b; HIST2H3C; Hist2h3c1;

Gene Symbols:
H3-3A, H3-3B, H3-5, H3C1, H3C10, H3C14, H3C15, H3C2, H3C7

Isotype:
IgG1

Purification Method:
Protein G

Product Type:
Antibody

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Fischer Scientific

7188989

Rabbit Polyclonal Antibody...


Antigen:
ELP3

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q9H9T3

Gene ID (Entrez):
55140

Immunogen:
This ELP3 antibody was raised against a peptide within the N-terminal half of human ELP3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
ELP3

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
2610507P14Rik; EC 2.3.1.48; elongation protein 3 homolog; elongator acetyltransferase complex subunit 3; Elongator complex protein 3; Elp3; h KAT9; hELP3; KAT9; LOC100362548; Protein lysine acetyltransferase ELP3; rCG52086-like; tRNA uridine(34) acetyltransferase

Gene Symbols:
ELP3

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

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Fischer Scientific

7188990

Rabbit Polyclonal Antibody...


Antigen:
NFkB p100

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
Q00653

Gene ID (Entrez):
4791

Immunogen:
This NFkB p100 antibody was raised against a peptide derived from the C-terminal region of human NFkB p100.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
NFKB2

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Gene Alias:
BOS_23394; CVID10; DNA-binding factor KBF2; H2TF1; Lymphocyte translocation chromosome 10 protein; lyt; LYT10; LYT-10; NF kappaB2; NF-kappaB2; NFKB, p52/p100 subunit; NFKB2; NF-kB2; nuclear factor kappa B subunit 2; nuclear factor Kappa-B, subunit 2; Nuclear factor NF-kappa-B p100 subunit; Nuclear factor NF-kappa-B p52 subunit; nuclear factor of Kappa light chain gene enhancer in B cells 2; nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2; nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100); nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100; Oncogene Lyt-10; OTTHUMP00000020371; p100; p105; p49; p49/p100; p50B; p52; RGD1307189; transcription factor NFKB2

Gene Symbols:
NFKB2

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody