7189011

Histone H3T11ph Polyclonal Antibody, Active Motif™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Histone H3T11ph

Applications

Dot Blot, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Immunogen

This Histone H3 phospho Thr11 antibody was raised against a peptide containing phospho-Thr11 of human histone H3.

Primary or Secondary

Primary

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Concentration

Lot-Specific

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype

IgG

Purification Method

Protein A

Product Type

Antibody

Description

  • Description Histone H3 is one of the DNA-binding proteins found in the chromatin of all eukaryotic cells
  • H3 along with four core histone proteins binds to DNA forming the structure of the nucleosome
  • Histones play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability
  • Post translationally, histones are modified in a variety of ways to either directly change the chromatin structure or allow for the binding of specific transcription factors
  • The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of post-translational modifications that influence cellular processes
  • These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

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Img

Fischer Scientific

7189011

Rabbit Polyclonal Antibody...


Antigen:
Histone H3T11ph

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This Histone H3 phospho Thr11 antibody was raised against a peptide containing phospho-Thr11 of human histone H3.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5

Isotype:
IgG

Purification Method:
Protein A

Product Type:
Antibody

Img

Fischer Scientific

7189013

Rabbit Polyclonal Antibody...


Antigen:
Histone macroH2A1.1

Applications:
Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This macroH2A1.1 antibody was raised against a peptide corresponding to amino acids 198-226 of human macroH2A1.1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7189014

Rabbit Polyclonal Antibody...


Antigen:
Phospho-SMC1 (Ser957)

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This SMC1 phospho Ser957 antibody was raised against a peptide containing phospho-serine 957 of human SMC1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody

Img

Fischer Scientific

7189014

Rabbit Polyclonal Antibody...


Antigen:
Phospho-SMC1 (Ser957)

Applications:
Dot Blot, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Immunogen:
This SMC1 phospho Ser957 antibody was raised against a peptide containing phospho-serine 957 of human SMC1.

Primary or Secondary:
Primary

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Concentration:
Lot-Specific

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8

Isotype:
IgG

Purification Method:
Antigen affinity chromatography

Product Type:
Antibody