7189023
c-Myc Monoclonal Antibody (6A10), Active Motif™
Rat Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
c-Myc
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols
MYC
Isotype
IgG2a
Purification Method
Protein G
Product Type
Antibody
Clone
6A10
Applications
Gel Shift, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rat
Target Species
Human
Gene Accession No.
P01106
Gene ID (Entrez)
4609
Immunogen
This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.
Primary or Secondary
Primary
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
MYC
Related Products
Description
- The c-Myc protein is a 62 kDa transcription factor that is encoded by the c-Myc gene on human chromosome 8q24
- c-Myc is commonly activated in a variety of tumor cells and plays an important role in cellular proliferation, differentiation, apoptosis and cell cycle progression
- The phosphorylation of c-Myc has been investigated and previous studies have suggested a functional association between phosphorylation at Thr58/Ser62 by glycogen synthase kinase 3, cyclin dependent kinase, ERK2 and C-Jun N terminal Kinase (JNK) in cell proliferation and cell cycle regulation
- Studies have shown that c-Myc is essential for vasculogenesis and angiogenesis in tumor development, which distributes blood throughout the cells
- The c-myc oncogene (p62 c-myc) is involved in the control of normal cellular proliferation and differentiation, and the deregulated expression of c-Myc induces apoptosis in different cell types
- Antibodies against c-myc epitopes recognize overexpressed proteins containing Myc epitope tag fused to either amino- or carboxy-termini of targeted proteins
- c-Myc-, N-Myc- and L-Myc-encoded proteins function in cell proliferation, differentiation and neoplastic disease
- Amplification of the c-Myc gene has been found in several types of human tumors including lung, breast and colon carcinomas, while the N-Myc gene has been found amplified in neuroblastomas
- Translocation of the c-myc locus on chromosome 8 to the immunoglobulin loci on chromosome 14 (heavy chain); 2 (delta light chain); or 22 (light chain) is described in Burkitts lymphoma and other B-cell lymphoproliferative conditions
- An aberrant expression of the c-myc gene occurs in tumors of different origins such as colorectal, gastric, gallbladder, hepatic, mammary, ovarian, endometrial, head and neck, pulmonary, prostatic, thyroidal, oral, ocular, nasopharyngeal, endocrine, as well as hematopoietic neoplasms.
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Antigen: c-Myc
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols: MYC
Isotype: IgG2a
Purification Method: Protein G
Product Type: Antibody
Clone: 6A10
Applications: Gel Shift, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rat
Target Species: Human
Gene Accession No.: P01106
Gene ID (Entrez): 4609
Immunogen: This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: MYC
Antigen:
c-Myc
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
AU016757; Avian myelocytomatosis viral (v-myc) oncogene homolog; avian myelocytomatosis viral oncogene homolog; BHLHE39; c Myc; Class E basic helix-loop-helix protein 39; c-Myc; c-myc proto-oncogene; mMyc; MRTL; Myc; Myc protein; Myc proto-oncogene protein; Myc2; MYCC; myc-related translation/localization regulatory factor; myelocytomatosis oncogene; myelocytomatosis viral oncogene homolog; Niard; Nird; Proto-oncogene c-Myc; RNCMYC; Transcription factor p64; v-myc avian myelocytomatosis viral oncogene homolog; v-myc myelocytomatosis viral oncogene homolog
Gene Symbols:
MYC
Isotype:
IgG2a
Purification Method:
Protein G
Product Type:
Antibody
Clone:
6A10
Applications:
Gel Shift, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Human
Gene Accession No.:
P01106
Gene ID (Entrez):
4609
Immunogen:
This c-Myc antibody was raised against a recombinant protein corresponding to amino acids 1-262 of human c-Myc protein.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MYC
Antigen: Histone H2A, C-terminal
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 1190022L06; Acetyl-Histone H2; AW228881; BOS_14476; BOS_21793; BOS_6451; dJ160A22.4; dJ86C11.1; gammaH2ax; h2a; H2A 615 antibody; H2A GL101 antibody; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A.1b; H2A.2; H2A.3; H2a.x; H2A.z; H2a.z-1; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2a/x; H2A/z; H2a-291A; H2a-53; h2a-A; H2ac11; H2ac13; H2AC15; H2AC16; H2AC17; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2afx; H2AFZ; H2AG; H2AH; H2ak; H2AK5ac; H2ax; H2AX histone; H2az; H2AZ histone; HIS; Hist1h2aa; Hist1h2ab; Hist1h2ac; HIST1H2AD; HIST1H2AE; HIST1H2AE antibody; HIST1H2AG; Hist1h2ah; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; Hist1h2an; Hist1h2ao; Hist1h2ap; Hist1h2ba; hist2h2ab; hist2h2ab.S; HIST3H2A; Hist5-2ax; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2aj; histone cluster 1, H2ba; histone cluster 2, H2ab S homeolog; histone H2A; Histone H2A type 1; Histone H2A type 1-B; Histone H2A type 1-B/E; Histone H2A type 1-C; Histone H2A type 1-D; Histone H2A type 1-E; Histone H2A type 1-G; Histone H2A type 1-H; Histone H2A type 1-I; Histone H2A type 1-J; Histone H2A type 1-N; Histone H2A type 1-O; Histone H2A type 1-P; Histone H2A type 4; Histone H2A, testis; Histone H2A.2; Histone H2A.3; Histone H2A.X; Histone H2A.Z; Histone H2A/a; Histone H2A/e; Histone H2A/g; Histone H2A/m; histone H2A/p; Histone H2A/ptl; Histone H2A/s; histone H2AD; histone H2AE; Histone H2AX; Histone H2B type 1-A; Histone H2B, testis; MGC74460 antibody; pH2A/f; RGD1566119; testis-specific histone 2a; testis-specific histone 2b; Testis-specific histone H2B; TH2A; Th2b; XELAEV_18004421mg; XH2AX
Gene Symbols: H2AC11, H2AC12, H2AC13, H2AC14, H2AC4, H2AC7, H2AC8, H2AX, H2AZ1
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P04908, P0C0S5, P0C0S8, P16104, P20671, Q96KK5, Q99878
Gene ID (Entrez): 3012, 3013, 3014, 3015, 8329, 8331, 8335, 85235, 8969
Immunogen: This Histone H2A, C-terminal antibody was raised against a peptide containing the C- terminal region of human histone H2A.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: H2AC12
Antigen:
Histone H2A, C-terminal
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
1190022L06; Acetyl-Histone H2; AW228881; BOS_14476; BOS_21793; BOS_6451; dJ160A22.4; dJ86C11.1; gammaH2ax; h2a; H2A 615 antibody; H2A GL101 antibody; H2A histone family member; H2A histone family member X; H2A histone family member Z; H2A histone family, member A; H2A histone family, member C; H2A histone family, member E; H2A histone family, member G; H2A histone family, member M; H2A histone family, member P; H2A histone family, member X; H2A histone family, member Z; H2A.1; H2A.1 antibody; H2A.1b; H2A.2; H2A.3; H2a.x; H2A.z; H2a.z-1; H2A/a; H2A/c; H2A/d; H2A/E; H2A/g; H2A/m; H2A/p; H2A/S; H2a/x; H2A/z; H2a-291A; H2a-53; h2a-A; H2ac11; H2ac13; H2AC15; H2AC16; H2AC17; H2ae; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFE; H2AFG; H2AFI; H2AFM; H2AFN; H2AFP; H2afx; H2AFZ; H2AG; H2AH; H2ak; H2AK5ac; H2ax; H2AX histone; H2az; H2AZ histone; HIS; Hist1h2aa; Hist1h2ab; Hist1h2ac; HIST1H2AD; HIST1H2AE; HIST1H2AE antibody; HIST1H2AG; Hist1h2ah; HIST1H2AI; HIST1H2AJ; HIST1H2AK; HIST1H2AL; HIST1H2AM; Hist1h2an; Hist1h2ao; Hist1h2ap; Hist1h2ba; hist2h2ab; hist2h2ab.S; HIST3H2A; Hist5-2ax; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ah; histone 1, H2ai; histone 1, H2aj; histone 1, H2ba; histone 2, H2ai; histone 5 protein 2ax; histone cluster 1, H2aa; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2aj; histone cluster 1, H2ba; histone cluster 2, H2ab S homeolog; histone H2A; Histone H2A type 1; Histone H2A type 1-B; Histone H2A type 1-B/E; Histone H2A type 1-C; Histone H2A type 1-D; Histone H2A type 1-E; Histone H2A type 1-G; Histone H2A type 1-H; Histone H2A type 1-I; Histone H2A type 1-J; Histone H2A type 1-N; Histone H2A type 1-O; Histone H2A type 1-P; Histone H2A type 4; Histone H2A, testis; Histone H2A.2; Histone H2A.3; Histone H2A.X; Histone H2A.Z; Histone H2A/a; Histone H2A/e; Histone H2A/g; Histone H2A/m; histone H2A/p; Histone H2A/ptl; Histone H2A/s; histone H2AD; histone H2AE; Histone H2AX; Histone H2B type 1-A; Histone H2B, testis; MGC74460 antibody; pH2A/f; RGD1566119; testis-specific histone 2a; testis-specific histone 2b; Testis-specific histone H2B; TH2A; Th2b; XELAEV_18004421mg; XH2AX
Gene Symbols:
H2AC11, H2AC12, H2AC13, H2AC14, H2AC4, H2AC7, H2AC8, H2AX, H2AZ1
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P04908, P0C0S5, P0C0S8, P16104, P20671, Q96KK5, Q99878
Gene ID (Entrez):
3012, 3013, 3014, 3015, 8329, 8331, 8335, 85235, 8969
Immunogen:
This Histone H2A, C-terminal antibody was raised against a peptide containing the C- terminal region of human histone H2A.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
H2AC12
Antigen: BCL11A
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias: 2810047E18Rik; B cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; Bcl11a; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; BOS_11500; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; Ctip1; D930021L15Rik; ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; EVI9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; mKIAA1809; myeloid leukemia; Zinc finger protein 856; ZNF856
Gene Symbols: BCL11A
Isotype: IgG1
Purification Method: Protein G
Product Type: Antibody
Clone: BCL11A/123
Applications: Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Human
Gene Accession No.: Q9H165
Gene ID (Entrez): 53335
Immunogen: This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: BCL11A
Antigen:
BCL11A
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 30% glycerol and 0.035% sodium azide; pH 7.5
Gene Alias:
2810047E18Rik; B cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; Bcl11a; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; BOS_11500; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; Ctip1; D930021L15Rik; ecotropic viral integration site 9 homolog; Ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; EVI9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; KIAA1809; mKIAA1809; myeloid leukemia; Zinc finger protein 856; ZNF856
Gene Symbols:
BCL11A
Isotype:
IgG1
Purification Method:
Protein G
Product Type:
Antibody
Clone:
BCL11A/123
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
Q9H165
Gene ID (Entrez):
53335
Immunogen:
This BCL11A antibody was raised against a recombinant protein corresponding to amino acids 637-835 of BCL11A-XL (B-cell lymphoma/leukemia 11A extra long form).
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
BCL11A
Antigen: SIRT6
Concentration: Lot-Specific
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias: 2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; SIRT6; sirtuin 6; sirtuin type 6
Gene Symbols: SIRT6
Isotype: IgG
Purification Method: Antigen affinity chromatography
Product Type: Antibody
Clone: __
Applications: Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q8N6T7
Gene ID (Entrez): 51548
Immunogen: This SIRT6 antibody was raised against a peptide within the C-terminus of human SIRT6.
Primary or Secondary: Primary
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: SIRT6
Antigen:
SIRT6
Concentration:
Lot-Specific
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
70mM tris with 0.07mM EDTA, 105mM NaCl, 30% glycerol, 31mM glycine and 0.035% sodium azide; pH 8
Gene Alias:
2810449N18Rik; AI043036; NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; SIR2; SIR2 like 6; Sir2l6; SIR2-like protein 6; sir2-related protein type 6; SIRT6; sirtuin 6; sirtuin type 6
Gene Symbols:
SIRT6
Isotype:
IgG
Purification Method:
Antigen affinity chromatography
Product Type:
Antibody
Clone:
__
Applications:
Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q8N6T7
Gene ID (Entrez):
51548
Immunogen:
This SIRT6 antibody was raised against a peptide within the C-terminus of human SIRT6.
Primary or Secondary:
Primary
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
SIRT6