7190518

Interferon gamma Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Interferon gamma

Applications

ELISA, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Bovine

Gene Accession No.

P07353

Gene ID (Entrez)

281237

Immunogen

This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to the 143 amino acids of the mature Bovine IFN Gamma protein.

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene

IFNG

Concentration

1 mg/mL

Classification

Polyclonal

Form

Lyophilized

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

BoIFNG; BOS_5228; cytokine; EGK_03901; gamma interferon; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; IFNG; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; Interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; Interferon?; M-IFN-g; R-IFN-g

Gene Symbols

IFNG

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at 4°C prior to restoration
  • For extended storage aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for bovine IFN gamma protein
  • A BLAST analysis was used to suggest cross-reactivity with IFN gamma from bovine based on 100% homology; cross-reactivity to yak, bison, zebu, buffalo, goat, sheep, nilgai, giraffe, Chinese forest musk deer, sika deer, red deer, Arabian camel, and Bactrian camel based on 91-99% homology with the immunizing sequence
  • Cross-reactivity with IFN gamma from other sources has not been determined
  • IFN gamma (Interferon gamma, Type II interferon) is a macrophage activation factor, and immune interferon that is produced primarily by T-lymphocytes and natural killer cells in response to antigens, mitogens, Staphylococcus enterotoxin B, phytohemaglutanin and other cytokines
  • IFN gamma is a dimeric protein consisting of two 146 amino acid subunits
  • IFN gamma is a glycoprotein that exists, functionally, as a homodimer of approximately 45 kDa
  • On SDS-PAGE, IFN gamma appears as a combination of 25, 20 and minor 15.5 kDa bands as a result of differential glycosylation
  • The biological activity of the IFN gamma homodimer is highly species specific
  • Human IFN gamma does not show cross-reactivity with mouse
  • IFN gamma function includes the following: antiviral activity, tumor antiproliferative activity, induction of class I and II MHC, macrophage activation, and enhanced immunoglobulin secretion by B lymphocytes
  • IFN gamma is involved in cytokine regulation and also acts synergistically with other cytokines
  • Activation of IFN gamma takes place through binding of IFN gamma receptor I and II, and activating the JAK-STAT pathway
  • IFN gamma does not show any homology with IFN alpha or IFN beta but human IFN gamma shows about 40% sequence homology with mouse IFN gamma
  • IFN gamma is upregulated by IL2, FGF basic, EGF and downregulated by vitamin D3 or DMN
  • IFN gamma gene mutations are associated with aplastic anemia.

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7190518

Rabbit Polyclonal Antibody...


Antigen:
Interferon gamma

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Bovine

Gene Accession No.:
P07353

Gene ID (Entrez):
281237

Immunogen:
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to the 143 amino acids of the mature Bovine IFN Gamma protein.

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
IFNG

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
BoIFNG; BOS_5228; cytokine; EGK_03901; gamma interferon; gamma-interferon; gamma-interferon precursor (AA -23 to 143); H-IFN-g; IFG; IFI; IFN gamma; IFN ?; IFNG; IFN-g; IFNG2; IFN-gamma; IFN-gamma precursor; IFN-y; IFN?; Immune interferon; Interferon gamma; interferon gamma precursor; interferon gamma type 2; Interferon y; Interferon ?; interferon, gamma; interferon-gama; interferon-gamma; Interferon-gamma level; Interferon?; M-IFN-g; R-IFN-g

Gene Symbols:
IFNG

Primary or Secondary:
Primary

Product Type:
Antibody

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7190519

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Antigen:
Protein A

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
HRP

Host Species:
Goat

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Protein A [Staphylococcus aureus]

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2

Gene Alias:
__

Gene Symbols:
__

Primary or Secondary:
Primary

Product Type:
Antibody

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7190525

Rabbit Polyclonal Antibody...


Antigen:
ERK2 Internal

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P28482, P63085, P63086

Gene ID (Entrez):
116590, 26413, 5594

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MAPK1

Concentration:
1.03 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
9030612K14Rik; AA407128; AU018647; C78273; ERK; Erk2; ERK-2; ERT1; Extracellular signal-regulated kinase 2; extracellular signal-regulated kinase-2; extracellular-signal-regulated kinase 2; MAP kinase 1; MAP kinase 2; MAP kinase isoform p42; Mapk; MAPK 1; MAPK 2; MAPK1; MAPK2; mitogen activated protein kinase 1; Mitogen-activated protein kinase 1; Mitogen-activated protein kinase 2; p38; p40; p41; p41mapk; p42mapk; p42-MAPK; PRKM1; PRKM2; protein tyrosine kinase ERK2

Gene Symbols:
MAPK1

Primary or Secondary:
Primary

Product Type:
Antibody

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Antigen:
Phospho-ATM (Ser1981)

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Sheep

Target Species:
Human

Gene Accession No.:
Q13315

Gene ID (Entrez):
472

Immunogen:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
ATM

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
AI256621; AT mutated; A-T mutated; A-T mutated homolog; AT mutated protein; AT1; ATA; Ataxia t; ataxia telangiectasia gene mutated in human beings; Ataxia telangiectasia mutated; Ataxia telangiectasia mutated homolog; ATC; ATD; ATDC; ATE; ATM; ATM (phospho S1981); ATM (pS1981); ATM (pSer1981); ATM phospho S1981; ATM phospho Ser1981; ATM serine/threonine kinase; C030026E19Rik; DKFZp781A0353; EC 2.7.1.37; MGC74674; phospho ATM; phospho S1981 ATM; Serine-protein kinase ATM; TEL1; TEL1, telomere maintenance 1, homolog; TELO1

Gene Symbols:
ATM

Primary or Secondary:
Primary

Product Type:
Antibody