7190650

MEK2 N-Term Monoclonal Antibody (19G10.F1.E2), Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MEK2 N-Term

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

AA589381; CFC4; dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; Map2k2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; Prkmk2; protein kinase, mitogen activated, kinase 2, p45

Gene Symbols

MAP2K2

Isotype

IgG2b κ

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

MAP2K2

Clone

19G10.F1.E2

Applications

ELISA, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human, Mouse, Rat

Gene Accession No.

P36506, P36507, Q63932

Gene ID (Entrez)

26396, 5605, 58960

Immunogen

Anti-MEK2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus conjugated to KLH.

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at -20°C prior to opening
  • This product is stable at 4°C as an undiluted liquid
  • For extended storage, aliquot contents and freeze at -20°C or below
  • Avoid cycles of freezing and thawing
  • Dilute only prior to immediate use
  • Cross reactivity is expected to occur with human, mouse, and rat based on sequence identity of the peptide immunogen
  • This antibody does not react with the MEK1 isoform
  • MEK1 (Mitogen activated protein kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases
  • MEK1 activates ERK1 and ERK2 MAP kinases
  • Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop
  • MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK
  • Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.

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Fischer Scientific

7190650

Mouse Monoclonal Antibody...


Antigen:
MEK2 N-Term

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
AA589381; CFC4; dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; Map2k2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; Prkmk2; protein kinase, mitogen activated, kinase 2, p45

Gene Symbols:
MAP2K2

Isotype:
IgG2b κ

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MAP2K2

Clone:
19G10.F1.E2

Applications:
ELISA, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human, Mouse, Rat

Gene Accession No.:
P36506, P36507, Q63932

Gene ID (Entrez):
26396, 5605, 58960

Immunogen:
Anti-MEK2 Monoclonal Antibody was produced in mice by repeated immunizations with synthetic peptide corresponding to amino acid residues near the N-terminus conjugated to KLH.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190653

Rabbit Polyclonal Antibody...


Antigen:
Methyl-Retinoblastoma K860 Me1 (Lys860)

Concentration:
0.99 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein

Gene Symbols:
RB1

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
RB1

Clone:
__

Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P06400

Gene ID (Entrez):
5925

Immunogen:
__

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190653

Rabbit Polyclonal Antibody...


Antigen:
Methyl-Retinoblastoma K860 Me1 (Lys860)

Concentration:
0.99 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; Rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; Retinoblastoma 1 (including osteosarcoma); retinoblastoma protein; retinoblastoma suspectibility protein; Retinoblastoma-associated protein

Gene Symbols:
RB1

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
RB1

Clone:
__

Applications:
Dot Blot, ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P06400

Gene ID (Entrez):
5925

Immunogen:
__

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190654

Rabbit Polyclonal Antibody...


Antigen:
IL-2

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Aldesleukin; BOS_16374; H-IL-2; IL2; IL-2; ILN; Interleukin; interleukin 2; Interleukin2; Interleukin-2; interleukin-2 precursor protein; involved in regulation of T-cell clonal expansion; lymphokine; M-IL-2; POIL2; T cell growth factor; T-cell growth factor; TCGF

Gene Symbols:
IL2

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
IL2

Clone:
__

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Feline

Gene Accession No.:
Q07885

Gene ID (Entrez):
751114

Immunogen:
This protein A purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a recombinant protein raised in yeast corresponding to 134 amino acids of mature cat IL-2.

Primary or Secondary:
Primary

Product Type:
Antibody