7190887

IDO1 Monoclonal Antibody (2E2.6), Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IDO1

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase

Gene Symbols

Ido1

Isotype

IgG1

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Ido1

Clone

2E2.6

Applications

ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Mouse

Gene Accession No.

P28776

Gene ID (Entrez)

15930

Immunogen

IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.

Primary or Secondary

Primary

Product Type

Antibody

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • IDO1 antibody is specific for mouse IDO1 protein
  • Mouse IDO1 does not react with human tissues
  • Cross-reactivity with IDO1 from other sources has not been determined
  • IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin
  • By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines
  • IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs)
  • In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction
  • The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms
  • Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites
  • Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

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Fischer Scientific

7190887

Mouse Monoclonal Antibody...


Antigen:
IDO1

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
EC 1.13.11.52; IDO; Ido1; IDO-1; Indo; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; Indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; Indoleamine-pyrrole 2,3-dioxygenase

Gene Symbols:
Ido1

Isotype:
IgG1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Ido1

Clone:
2E2.6

Applications:
ELISA, Flow Cytometry, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Mouse

Gene Accession No.:
P28776

Gene ID (Entrez):
15930

Immunogen:
IDO1 antibody was produced in mouse by repeated immunizations with mouse recombinant IDO1 protein followed by hybridoma development.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190888

Rabbit Polyclonal Antibody...


Antigen:
Streptavidin

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Clone:
__

Applications:
Dot Blot, ELISA, Immunofluorescence, Western Blot

Conjugate:
Rhodamine

Host Species:
Rabbit

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Streptavidin (Streptomyces avidinii)

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190888

Rabbit Polyclonal Antibody...


Antigen:
Streptavidin

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Clone:
__

Applications:
Dot Blot, ELISA, Immunofluorescence, Western Blot

Conjugate:
Rhodamine

Host Species:
Rabbit

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Streptavidin (Streptomyces avidinii)

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190889

Mouse Monoclonal Antibody...


Antigen:
LGR4

Concentration:
1.13 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
9130225G07; A330106J01Rik; A930009A08Rik; BNMD17; G protein-coupled receptor 48; G protein-coupled receptor GPR48; GPR48; G-protein coupled receptor 48; leucine rich repeat containing G protein-coupled receptor 4; leucine-rich repeat containing G protein-coupled receptor 4; leucine-rich repeat-containing G protein-coupled receptor 4; Leucine-rich repeat-containing G-protein coupled receptor 4; LGR4

Gene Symbols:
LGR4

Isotype:
IgG2b κ

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
LGR4

Clone:
6G8.B3.G5.C3

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Chimpanzee, Human, Rhesus Monkey

Gene Accession No.:
Q9BXB1

Gene ID (Entrez):
451088, 55366, 701736

Immunogen:
This monoclonal antibody was produced by repeated immunizations with a synthetic peptide corresponding to an internal region of human LGR4 protein. The hybridoma was produced by fusing BALB/c mouse splenocytes and mouse myeloma SP2/O cells using conventional technology.

Primary or Secondary:
Primary

Product Type:
Antibody