7190954

IL-6 Monoclonal Antibody (33A12.G9), Rockland™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-6

Concentration

1 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6

Gene Symbols

Il6

Isotype

IgG1 κ

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

Il6

Clone

33A12.G9

Applications

ELISA, Flow Cytometry, Western Blot

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Accession No.

P05231

Gene ID (Entrez)

3569

Immunogen

This Protein A purified IL-6 monoclonal antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-6 produced in E.coli followed by hybridoma development.

Primary or Secondary

Primary

Product Type

Antibody

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Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This purified antibody detects recombinant and native IL-6 present in body fluids and cell supernatants in various assays (ie
  • IL-1 stimulated IL-6 production from fibroblasts)
  • In Western blot analysis of natural cell products or human body fluids, multiple bands of IL-6 will appear due to the variable amount of glycosylation on the molecule
  • Interleukin 6 (IL-6) is a multifunctional 26 kD protein originally discovered in the medium of RNA-stimulated fibroblastoid cells
  • IL-6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be important as IL-1 and TNF-a in regulating the acute phase response
  • IL-6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages and endothelial cells
  • IL-6 acts upon a variety of cells including myeloid progenitor cells, T cells, B cells, and hepatocytes
  • In addition, IL-6 appears to interact with IL-2 in the proliferation of T lymphocytes
  • IL-6 potentiates the proliferative effect of IL-3 on multipotential hematopoietic progenitors
  • IL-6 plays a critical role in B-cell differentiation to plasma cells and is a potent growth factor for plasmacytoma and myeloma
  • IL-6 is a very useful culture supplement for the generation of a high number of antibody-producing hybridomas
  • Primarily produced at sites of acute and chronic inflammation, IL-6 is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha
  • The functioning of IL-6 is implicated in a wide variety of inflammation-associated disease states including diabetes mellitus and systemic juvenile rheumatoid arthritis.

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Fischer Scientific

7190954

Mouse Monoclonal Antibody...


Antigen:
IL-6

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
B-cell differentiation factor; B-cell hybridoma growth factor; B-cell stimulatory factor 2; BOS_4106; BSF2; BSF-2; CDF; ChIL-6; CTL differentiation factor; EGM_12696; HGF; H-IL-6; HSF; Hybridoma growth factor; hypothetical protein; IFNB2; IFN-beta-2; IL6; Il-6; ILg6; ILN; Interferon beta-2; Interleukin; interleukin 6; Interleukin 6 (interferon, beta 2); interleukin BSF-2; Interleukin HP-1; Interleukin6; Interleukin-6; interleukin-6 protein; M-IL-6; R-IL-6

Gene Symbols:
Il6

Isotype:
IgG1 κ

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
Il6

Clone:
33A12.G9

Applications:
ELISA, Flow Cytometry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P05231

Gene ID (Entrez):
3569

Immunogen:
This Protein A purified IL-6 monoclonal antibody was produced in mouse by repeated immunizations with mature full length recombinant human IL-6 produced in E.coli followed by hybridoma development.

Primary or Secondary:
Primary

Product Type:
Antibody

Img

Fischer Scientific

7190955

Goat Polyclonal Antibody...


Antigen:
Sarcosine Oxidase

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

Clone:
__

Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Goat

Target Species:
Bacteria

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
Sarcosine Oxidase [Microbial]

Primary or Secondary:
Primary

Product Type:
Antibody

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Fischer Scientific

7190957

Rabbit Polyclonal Antibody...


Antigen:
PRDM1 BLIMP1

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
B lymphocyte-induced maturation protein 1; b2b1765Clo; Beta-interferon gene positive regulatory domain I-binding factor; beta-interferon gene positive-regulatory domain I binding factor; BLIMP 1; Blimp1; BLIMP-1; B-lymphocyte-induced maturation protein 1; MGC118922; MGC118923; MGC118924; MGC118925; OTTHUMP00000016918; OTTHUMP00000202173; Positive regulatory domain I-binding factor 1; PR domain 1; PR domain containing 1, with ZNF domain; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI BF1; PRDI-BF1; PRDI-binding factor-1; Prdm1; RP1-134E15.1; ZNFPR1A1

Gene Symbols:
PRDM1

Isotype:
__

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
PRDM1

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Canine, Human, Mouse, Rat

Gene Accession No.:
O75626, Q60636

Gene ID (Entrez):
12142, 309871, 481947, 639

Immunogen:
__

Primary or Secondary:
Primary

Product Type:
Antibody

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7190958

Goat Polyclonal Antibody...


Antigen:
CRP

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
Aa1249; Ab1-341; Ab2-196; Ac1-114; Ac1262; Ac2-069; AI255847; Ba2-693; C-reactive protein; C-reactive protein member of the pentraxin family; C-reactive protein(1-205); C-reactive protein, member of the pentraxin family; C-reactive protein, pentraxin-related; C-reactive protein, petaxin related; C-reactive protein-like; CRP; CRP1; CSRP; CYRP; D1S181E; DKFZp686M148; DKFZp686M149; LOC100620468; MGC149895; MGC88244; pentraxin 1; PTX1; RP11-419N10.4

Gene Symbols:
Crp

Isotype:
__

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
Crp

Clone:
__

Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot

Conjugate:
Unconjugated

Host Species:
Goat

Target Species:
Human

Gene Accession No.:
P02741

Gene ID (Entrez):
1401

Immunogen:
Capsular Reactive Protein (CRP) [Human Serum]

Primary or Secondary:
Primary

Product Type:
Antibody