7190963

Cripto-1 TDGF1 Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

Cripto-1 TDGF1

Applications

ELISA, Immunohistochemistry, Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human

Gene Accession No.

P13385

Gene ID (Entrez)

6997

Primary or Secondary

Primary

Product Type

Antibody

Concentration

0.97 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; Cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; Epidermal growth factor-like cripto protein CR1; TDGF1; TDGF2; teratocarcinoma-derived growth factor; Teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)

Gene Symbols

TDGF1

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

TDGF1

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • This antibody is specific for human Cripto-1 protein
  • A BLAST analysis was used to suggest limited cross-reactivity with Cripto-1 from mouse based on a 70% homology with the immunizing sequence
  • Expect cross-reactivity with human Cripto-3 (TDGF2) based on very high levels of sequence conservation
  • Cross-reactivity with Cripto-1 from other sources has not been determined
  • Cripto (TDGF1) is a GPI-anchored cell membrane proetin involved in Nodal signaling
  • Cell associated TDGF1 acts as a a Nodeal coreceptor in cis
  • Shedding of TDGF1 by TMEM8A modulated Nodal signaling by allowing soluble TDGF1 to act as a Nodal coreceptor on other cells
  • TDGF1 is expressed both in ES cells and during the early phases of embryo development, while in adults it is reactivated in a wide range of epithelial cancers.

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Fischer Scientific

7190963

Rabbit Polyclonal Antibody...


Antigen:
Cripto-1 TDGF1

Applications:
ELISA, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Rabbit

Target Species:
Human

Gene Accession No.:
P13385

Gene ID (Entrez):
6997

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
0.97 mg/mL

Classification:
Polyclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
CR; CR1; CRGF; CRIPTO; cripto growth factor; Cripto-1; Cripto-1 growth factor; Cripto-3; epidermal growth factor-like Cripto protein; Epidermal growth factor-like cripto protein CR1; TDGF1; TDGF2; teratocarcinoma-derived growth factor; Teratocarcinoma-derived growth factor 1; TERATOCARCINOMA-DERIVED GROWTH FACTOR PRECURSOR (EPIDERMAL GROWTH FACTOR-LIKE CRIPTO PROTEIN) (CRIPTO GROWTH FACTOR)

Gene Symbols:
TDGF1

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
TDGF1

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Fischer Scientific

7190964

Rabbit Polyclonal Antibody...


Antigen:
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Applications:
ELISA, Immunoprecipitation, Western Blot

Conjugate:
HRP

Host Species:
Rabbit

Target Species:
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Gene Accession No.:
__

Gene ID (Entrez):
__

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Polyclonal

Form:
Lyophilized

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2

Gene Alias:
Urea Amidohydrolase

Gene Symbols:
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Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Gene:
__

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7190966

Mouse Monoclonal Antibody...


Antigen:
Mesothelin

Applications:
ELISA, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q13421

Gene ID (Entrez):
10232

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; Mpf; Msln; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein

Gene Symbols:
MSLN

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
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Img

Fischer Scientific

7190966

Mouse Monoclonal Antibody...


Antigen:
Mesothelin

Applications:
ELISA, Immunohistochemistry, Western Blot

Conjugate:
Unconjugated

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q13421

Gene ID (Entrez):
10232

Primary or Secondary:
Primary

Product Type:
Antibody

Concentration:
1 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias:
CAK1; CAK1 antigen; megakaryocyte potentiating factor; Megakaryocyte-potentiating factor; Mes; Mesothelin; Mesothelin, cleaved form; Mpf; Msln; Pre-pro-megakaryocyte-potentiating factor; SMR; SMRP; soluble MPF mesothelin related protein

Gene Symbols:
MSLN

Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles

Gene:
MSLN