7190987
TNF alpha Polyclonal Antibody, Rockland™
Rabbit Polyclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
TNF alpha
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Rabbit
Target Species
Human, Non-human Primate
Gene Accession No.
P01375
Gene ID (Entrez)
7124
Immunogen
The whole rabbit serum was prepared by repeated immunizations with recombinant human TNFa produced in E.coli.
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
Tnf
Concentration
75 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
Antibody with no preservative; pH
Gene Alias
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Gene Symbols
Tnf
Primary or Secondary
Primary
Product Type
Antibody
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- The antiserum is directed against mature 17,000 MW human TNFa and is useful in determining its presence in various assays
- In general, this antibody also detects primate TNFa in the same formats using similar dilutions
- The antibody does not recognize human TNFb (lymphotoxin)
- This antiserum will recognize the cell-bound precursor of TNFa as a 26,000 protein in immunoblots, particularly in denatured samples
- This antibody is also useful for neutralization of human and primate TNFa activity in bioassays
- It does not neutralize the biological activity of lymphotoxin
- For neutralization, it is recommended to incubate the sample with a 1:200 dilution of the antibody for at least 4 hours before being tested
- A control of similarly diluted normal rabbit IgG is recommended
- TNF alpha is a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily
- This cytokine is mainly secreted by macrophage and bind to its receptors, TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR
- TNF alpha is involved in the regulation of immune cells, cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation
- TNF alpha exists as a multimer of two, three, or five noncovalently linked units, but shows a single 17 kDa band following SDS-PAGE under non-reducing conditions
- Knockout studies in mice also suggested the neuroprotective function of TNF alpha, and has been observed to causes tumor necrosis when injected into tumor-bearing mice
- Other functions of TNF-alpha include its role in the immune response to bacterial, viral, parasitic and certain fungal infections, as well as its role in the necrosis of specific tumors
- TNF alpha causes cytolysis or cytostasis of certain transformed cells, being synergistic with interferon-gamma in its cytotoxicity
- This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer.
Compare Similar Items
Show Difference
Antigen: TNF alpha
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human, Non-human Primate
Gene Accession No.: P01375
Gene ID (Entrez): 7124
Immunogen: The whole rabbit serum was prepared by repeated immunizations with recombinant human TNFa produced in E.coli.
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Tnf
Concentration: 75 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: Antibody with no preservative; pH
Gene Alias: APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Gene Symbols: Tnf
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
TNF alpha
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Non-human Primate
Gene Accession No.:
P01375
Gene ID (Entrez):
7124
Immunogen:
The whole rabbit serum was prepared by repeated immunizations with recombinant human TNFa produced in E.coli.
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Tnf
Concentration:
75 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
Antibody with no preservative; pH
Gene Alias:
APC1 protein; BOS_21587; Cachectin; C-domain 1; C-domain 2; cTNF; DADB-70P7.1; DIF; ICD1; ICD2; Intracellular domain 1; Intracellular domain 2; N-terminal fragment; NTF; RATTNF; SBAB-548A10.2; Tnf; TNF alpha; TNF superfamily; TNF a; TNF, macrophage-derived; TNF, monocyte-derived; Tnfa; TNF-a; TNFalpha; TNF-alpha; Tnfsf1a; Tnfsf2; TNFa; TNLG1F; Tumor necrosis factor; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; tumor necrosis factor alpha (cachetin); tumor necrosis factor ligand 1F; Tumor necrosis factor ligand superfamily member 2; Tumor necrosis factor, membrane form; Tumor necrosis factor, soluble form; tumor necrosis factor-alpha; tumor-necrosis factor; tumour necrosis factor
Gene Symbols:
Tnf
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Phospho Enol Pyruvate Carboxylase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Plant
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Phospho-enol-pyruvate Carboxylase [Maize Leaves]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Phospho Enol Pyruvate Carboxylase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Plant
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Phospho-enol-pyruvate Carboxylase [Maize Leaves]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Phospho Enol Pyruvate Carboxylase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Rabbit
Target Species: Plant
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Phospho-enol-pyruvate Carboxylase [Maize Leaves]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Phospho Enol Pyruvate Carboxylase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Rabbit
Target Species:
Plant
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Phospho-enol-pyruvate Carboxylase [Maize Leaves]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Luciferase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Biotin
Host Species: Goat
Target Species: Firefly
Gene Accession No.: __
Gene ID (Entrez): __
Immunogen: Luciferase [Photinus pyralis (Firefly)]
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias: Firefly Luciferase; Genji firefly; Green Luciferase; Japanese firefly; Photinus pyralis
Gene Symbols: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Luciferase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Biotin
Host Species:
Goat
Target Species:
Firefly
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Luciferase [Photinus pyralis (Firefly)]
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% sodium azide; pH 7.2
Gene Alias:
Firefly Luciferase; Genji firefly; Green Luciferase; Japanese firefly; Photinus pyralis
Gene Symbols:
__
Primary or Secondary:
Primary
Product Type:
Antibody