7191053
EBI3 Monoclonal Antibody (V1.4F5.25), Rockland™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
IL-35 EBI3
Concentration
1 mg/mL
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols
Ebi3, IL27
Isotype
IgG2b
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
IL27
Clone
V1.4F5.25
Applications
ELISA, Immunoprecipitation, Western Blot
Conjugate
Unconjugated
Host Species
Mouse
Target Species
Mouse
Gene Accession No.
O35228, Q8K3I6
Gene ID (Entrez)
246779, 50498
Immunogen
Anti-EBI-3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.
Primary or Secondary
Primary
Product Type
Antibody
Related Products
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This antibody is specific for mouse EBI3 protein
- A BLAST analysis was used to suggest cross-reactivity with EBI3 from mouse sources based on 100% homology with the immunizing sequence
- Cross-reactivity with EBI-3 from other sources has not been determined
- IL-27 (Interleukin 27) is a cytokine belonging to the IL-12 family, and is a heterodimeric cytokine composed of EBI3 and p28 subunits
- IL-27 is produced by activated dendritic cells and macrophages in response to Toll-like receptor ligands and pro-inflammatory cytokines
- IL-27 promotes CD4+ T cell differentiation to the Th1 lineage by inducing expression of the transcription factor T-bet and up regulating IL-12R beta2, which in turn suppresses Th2 and Th17 differentiation and proliferation
- IL-27 is a recently discovered member of the IL-6/IL-12 family of proinflammatory and immunoregulatory cytokines
- IL-27 acts by binding to its receptor WSX-1 and gp130 which results in the activation of a Jak/STAT signaling cascade, suggesting IL-27 involvement in the regulation of immune processes
- It has been suggested that IL-27 can also be used as a therapeutic agent against cancer as it can also induce tumor-specific anti-tumor activity mediated through CD8+ T-cells, IFN-gamma, and T-bet
- In humans, the gene is located on the p arm of chromosome 16.
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Antigen: IL-35 EBI3
Concentration: 1 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols: Ebi3, IL27
Isotype: IgG2b
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: IL27
Clone: V1.4F5.25
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: O35228, Q8K3I6
Gene ID (Entrez): 246779, 50498
Immunogen: Anti-EBI-3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
IL-35 EBI3
Concentration:
1 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
cytokine receptor; EBI3; EBI-3; EBV-induced gene 3 protein; Epstein-Barr virus induced 3; Epstein-Barr virus induced gene 3; Epstein-Barr virus induced gene 3 (similar to Interleukin-27 beta chain precursor); Epstein-Barr virus-induced gene 3 protein; Epstein-Barr virus-induced gene 3 protein homolog; Il27; IL-27; IL27 p28; IL-27 p28 subunit; IL27 subunit; IL-27 subunit alpha; IL-27 subunit beta; Il27a; IL-27A; IL-27-A; IL27-A; IL27B; IL-27B; IL27p28; IL-27p28; IL30; IL35 subunit; ILN; Interleukin; interleukin 27; interleukin 30; Interleukin-27 subunit alpha; Interleukin-27 subunit beta; Interleukin-30; MGC71873; M-IL-27 (p28); p28; RGD1561420
Gene Symbols:
Ebi3, IL27
Isotype:
IgG2b
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
IL27
Clone:
V1.4F5.25
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
O35228, Q8K3I6
Gene ID (Entrez):
246779, 50498
Immunogen:
Anti-EBI-3 (MOUSE) Monoclonal Antibody was produced in mouse by repeated immunizations with mature full length recombinant mouse EBI-3 produced in E.coli followed by hybridoma development.
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: PIK3CB
Concentration: 1.09 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 1110001J02Rik; AI447572; catalytic phosphatidylinositol 3-kinase beta; p110beta; phosphatidylinositol 3-kinase catalytic subunit beta isoform; phosphatidylinositol 3-kinase, catalytic subunit, beta isoform; phosphatidylinositol 3-kinase, catalytic, beta polypeptide; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; phosphoinositide-3-kinase, catalytic, beta polypeptide; PI3K; PI3KBETA; PI3K-beta; PI3-kinase p110 subunit beta; PI3-kinase subunit beta; PIK3C1; PIK3CB; ptdIns-3-kinase p110; ptdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta
Gene Symbols: PIK3CB
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: PIK3CB
Clone: __
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: P42338
Gene ID (Entrez): 5291
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
PIK3CB
Concentration:
1.09 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
1110001J02Rik; AI447572; catalytic phosphatidylinositol 3-kinase beta; p110beta; phosphatidylinositol 3-kinase catalytic subunit beta isoform; phosphatidylinositol 3-kinase, catalytic subunit, beta isoform; phosphatidylinositol 3-kinase, catalytic, beta polypeptide; Phosphatidylinositol 4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform; phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; phosphoinositide-3-kinase, catalytic, beta polypeptide; PI3K; PI3KBETA; PI3K-beta; PI3-kinase p110 subunit beta; PI3-kinase subunit beta; PIK3C1; PIK3CB; ptdIns-3-kinase p110; ptdIns-3-kinase subunit beta; PtdIns-3-kinase subunit p110-beta
Gene Symbols:
PIK3CB
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
PIK3CB
Clone:
__
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
P42338
Gene ID (Entrez):
5291
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: Carbonic Anhydrase II
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias: AI131712; CA II; Ca2; CAC; CAII; CA-II; Car2; Car-2; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; epididymis luminal protein 76; epididymis secretory protein Li 282; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
Gene Symbols: CA2
Isotype: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: CA2
Clone: __
Applications: Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate: HRP
Host Species: Rabbit
Target Species: Bovine
Gene Accession No.: P00921
Gene ID (Entrez): 280740
Immunogen: Carbonic Anhydrase II [Bovine Erythrocytes]
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
Carbonic Anhydrase II
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
AI131712; CA II; Ca2; CAC; CAII; CA-II; Car2; Car-2; Carbonate dehydratase II; Carbonic anhydrase 2; carbonic anhydrase B; Carbonic anhydrase C; Carbonic anhydrase II; carbonic dehydratase; epididymis luminal protein 76; epididymis secretory protein Li 282; HEL-76; HEL-S-282; Ltw-5; Lvtw-5
Gene Symbols:
CA2
Isotype:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
CA2
Clone:
__
Applications:
Dot Blot, ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Bovine
Gene Accession No.:
P00921
Gene ID (Entrez):
280740
Immunogen:
Carbonic Anhydrase II [Bovine Erythrocytes]
Primary or Secondary:
Primary
Product Type:
Antibody
Antigen: NEUROD1
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; Beta-cell E-box transcriptional activator 2; BHF1; BHF-1; BHLHA3; Class A basic helix-loop-helix protein 3; MODY6; NEUROD; NEUROD1; neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1
Gene Symbols: NEUROD1
Isotype: __
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: NEUROD1
Clone: __
Applications: ELISA, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human
Gene Accession No.: Q13562
Gene ID (Entrez): 4760
Immunogen: __
Primary or Secondary: Primary
Product Type: Antibody
Antigen:
NEUROD1
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
Basic helix-loop-helix factor 1; basic helix-loop-helix transcription factor; Beta2; beta-cell E-box transactivator 2; Beta-cell E-box transcriptional activator 2; BHF1; BHF-1; BHLHA3; Class A basic helix-loop-helix protein 3; MODY6; NEUROD; NEUROD1; neurogenic differentiation 1; Neurogenic differentiation factor 1; neurogenic helix-loop-helix protein NEUROD; neuronal differentiation 1
Gene Symbols:
NEUROD1
Isotype:
__
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
NEUROD1
Clone:
__
Applications:
ELISA, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human
Gene Accession No.:
Q13562
Gene ID (Entrez):
4760
Immunogen:
__
Primary or Secondary:
Primary
Product Type:
Antibody