7191193
GRK2 Polyclonal Antibody, Rockland™
Goat Polyclonal Antibody
Manufacturer: Fischer Scientific
The price for this product is unavailable. Please request a quote
Antigen
GRK2
Applications
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate
Unconjugated
Host Species
Goat
Target Species
Human, Mouse
Gene Accession No.
P25098, Q99MK8
Gene ID (Entrez)
110355, 156
Primary or Secondary
Primary
Product Type
Antibody
Concentration
0.89 mg/mL
Classification
Polyclonal
Form
Liquid
Regulatory Status
RUO
Formulation
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias
Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Gene Symbols
GRK2
Content And Storage
-20°C, Avoid Freeze/Thaw Cycles
Gene
GRK2
Description
- Store vial at -20°C prior to opening
- Aliquot contents and freeze at -20°C or below for extended storage
- Avoid cycles of freezing and thawing
- Centrifuge product if not completely clear after standing at room temperature
- This product is stable for several weeks at 4°C as an undiluted liquid
- Dilute only prior to immediate use
- This affinity purified antibody is directed against human GRK2
- A BLAST analysis of the sequence shows 100% reactivity to human, and 90% to rat, mouse, and golden hamster
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., ?2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs ,regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
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Antigen: GRK2
Applications: ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Human, Mouse
Gene Accession No.: P25098, Q99MK8
Gene ID (Entrez): 110355, 156
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 0.89 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Gene Symbols: GRK2
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: GRK2
Antigen:
GRK2
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Human, Mouse
Gene Accession No.:
P25098, Q99MK8
Gene ID (Entrez):
110355, 156
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
0.89 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
Adrbk1; Adrbk-1; adrenergic beta receptor kinase 1; adrenergic receptor kinase, beta 1; adrenergic, beta, receptor kinase 1; BARK; BARK1; Bark-1; beta ARK; Beta-adrenergic receptor kinase 1; beta-adrenergic receptor kinase 1 beta ARK1; beta-AR kinase-1; betaARK1; BETA-ARK1; Beta-ARK-1; EC 2.7.1.126; G protein-coupled receptor kinase 2; G-protein coupled receptor kinase 2; G-protein-coupled receptor kinase 2; GRK2; GRK-2
Gene Symbols:
GRK2
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
GRK2
Antigen: NEMO/IKK-gamma
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Rabbit
Target Species: Human
Gene Accession No.: Q9Y6K9
Gene ID (Entrez): 8517
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1.1 mg/mL
Classification: Polyclonal
Form: Liquid
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: 1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; IkB kinase-associated protein 1; Ikbkg; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; Inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; NEMO; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Gene Symbols: Ikbkg
Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
Gene: Ikbkg
Antigen:
NEMO/IKK-gamma
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Accession No.:
Q9Y6K9
Gene ID (Entrez):
8517
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1.1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
1110037D23Rik; AI848108; AI851264; AMCBX1; AW124339; FIP3; FIP-3; Fip3p; I-kappa-B kinase gamma; I-kappa-B kinase subunit gamma; ikB kinase subunit gamma; IkB kinase-associated protein 1; Ikbkg; IKK[g]; IKK3; IKKAP1; IKKG; IKK-gamma; IMD33; incontinentia pigmenti; inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma; inhibitor of kappaB kinase gamma; Inhibitor of nuclear factor kappa-B kinase subunit gamma; IP; IP1; IP2; IPD2; mF; mFIP-3; NEMO; NF-kappa B essential modulator; NF-kappa-B essential modifier; NF-kappa-B essential modulator; OTTHUMP00000207079; OTTHUMP00000212188; ZC2HC9
Gene Symbols:
Ikbkg
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
Ikbkg
Antigen: Glycerol Kinase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: ASTP; ATP:glycerol 3-phosphotransferase; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; BOS_26177; D930012N15Rik; EC 2.7.1.30; Gk; GK 3; GK1; GK3P; GKD; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; glycerol kinase-like; Glycerolkinase; Gyk; LOC100354726
Gene Symbols: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Antigen:
Glycerol Kinase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
ASTP; ATP:glycerol 3-phosphotransferase; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; BOS_26177; D930012N15Rik; EC 2.7.1.30; Gk; GK 3; GK1; GK3P; GKD; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; glycerol kinase-like; Glycerolkinase; Gyk; LOC100354726
Gene Symbols:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__
Antigen: Glycerol Kinase
Applications: ELISA, Immunoprecipitation, Western Blot
Conjugate: Unconjugated
Host Species: Goat
Target Species: Bacteria
Gene Accession No.: __
Gene ID (Entrez): __
Primary or Secondary: Primary
Product Type: Antibody
Concentration: 1 mg/mL
Classification: Polyclonal
Form: Lyophilized
Regulatory Status: RUO
Formulation: 0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias: ASTP; ATP:glycerol 3-phosphotransferase; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; BOS_26177; D930012N15Rik; EC 2.7.1.30; Gk; GK 3; GK1; GK3P; GKD; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; glycerol kinase-like; Glycerolkinase; Gyk; LOC100354726
Gene Symbols: __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene: __
Antigen:
Glycerol Kinase
Applications:
ELISA, Immunoprecipitation, Western Blot
Conjugate:
Unconjugated
Host Species:
Goat
Target Species:
Bacteria
Gene Accession No.:
__
Gene ID (Entrez):
__
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
ASTP; ATP:glycerol 3-phosphotransferase; ATP-stimulated glucocorticoid-receptor translocation promoter; ATP-stimulated glucocorticoid-receptor translocaton promoter; BOS_26177; D930012N15Rik; EC 2.7.1.30; Gk; GK 3; GK1; GK3P; GKD; GKl; GKP3; GKTB; glycerokinase; Glycerokinase 3; Glycerol kinase; glycerol kinase-like; Glycerolkinase; Gyk; LOC100354726
Gene Symbols:
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
__