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7191199

MEK2 C-Term Polyclonal Antibody, Rockland™

Rabbit Polyclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

MEK2 C-Term

Applications

ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot

Conjugate

Unconjugated

Host Species

Rabbit

Target Species

Human, Mouse, Rat

Gene Accession No.

P36506, P36507, Q63932

Gene ID (Entrez)

26396, 5605, 58960

Primary or Secondary

Primary

Product Type

Antibody

Concentration

1.09 mg/mL

Classification

Polyclonal

Form

Liquid

Regulatory Status

RUO

Formulation

0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2

Gene Alias

AA589381; CFC4; dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; Map2k2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; Prkmk2; protein kinase, mitogen activated, kinase 2, p45

Gene Symbols

MAP2K2

Content And Storage

-20°C, Avoid Freeze/Thaw Cycles

Gene

MAP2K2

Description

  • Store vial at -20°C prior to opening
  • Aliquot contents and freeze at -20°C or below for extended storage
  • Avoid cycles of freezing and thawing
  • Centrifuge product if not completely clear after standing at room temperature
  • This product is stable for several weeks at 4°C as an undiluted liquid
  • Dilute only prior to immediate use
  • Directed against human MEK2 protein
  • Cross reactivity is expected to occur with human, mouse and rat based on sequence identity of the peptide immunogen
  • This antibody does not react with the MEK1 isoform
  • MEK1 (Mitogen activated protein kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases
  • MEK1 activates ERK1 and ERK2 MAP kinases
  • Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop
  • MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK
  • Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.

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Fischer Scientific

7191199

Rabbit Polyclonal Antibody...

Antigen:
MEK2 C-Term
Applications:
ELISA, Immunohistochemistry, Immunohistochemistry (Paraffin), Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse, Rat
Gene Accession No.:
P36506, P36507, Q63932
Gene ID (Entrez):
26396, 5605, 58960
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1.09 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
AA589381; CFC4; dual specificity mitogen activated protein kinase kinase 2; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; Map2k2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; Prkmk2; protein kinase, mitogen activated, kinase 2, p45
Gene Symbols:
MAP2K2
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
MAP2K2

Img

Fischer Scientific

7191201

Rabbit Polyclonal Antibody...

Antigen:
MEK1 C-Term
Applications:
ELISA, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Human, Mouse, Rat
Gene Accession No.:
P31938, Q01986, Q02750
Gene ID (Entrez):
170851, 26395, 5604
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; MAP2K1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Gene Symbols:
Map2k1
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
Map2k1

Img

Fischer Scientific

7191201

Rabbit Polyclonal Antibody...

Antigen:
MEK1 C-Term
Applications:
ELISA, Western Blot
Conjugate:
HRP
Host Species:
Rabbit
Target Species:
Human, Mouse, Rat
Gene Accession No.:
P31938, Q01986, Q02750
Gene ID (Entrez):
170851, 26395, 5604
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Lyophilized
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl, 10 mg/mL BSA and 0.01% gentamicin sulfate; pH 7.2
Gene Alias:
CFC3; dual specificity mitogen activated protein kinase kinase 1; Dual specificity mitogen-activated protein kinase kinase 1; EC 2.7.12.2; ERK activator kinase 1; kinase MEK1; MAP kinase kinase 1; MAP kinase kinase or Erk Kinase, Dual specificity mitogen-activated protein kinase kinase, involved in ras mediated vulval induction, LEThal LET-537 (42.8 kD) (mek-2); MAP kinase/Erk kinase 1; MAP2K1; map2k1.L; MAPK/ERK kinase 1; MAPKK 1; MAPKK1; MEK 1; Mek1; MEK2; mek-2; MEKK1; mitogen activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1; mitogen-activated protein kinase kinase 1 L homeolog; MKK (Thr292); MKK (Thr386); MKK1; MKK2; MP2K1; Prkmk1; PRKMK2; protein kinase, mitogen activated, kinase 1, p45; protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1); XELAEV_18018447mg
Gene Symbols:
Map2k1
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Gene:
Map2k1

Img

Fischer Scientific

7191207

Rabbit Polyclonal Antibody...

Antigen:
Zic-1
Applications:
ELISA, Immunofluorescence, Immunohistochemistry, Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human, Mouse
Gene Accession No.:
P46684, Q15915
Gene ID (Entrez):
22771, 7545
Primary or Secondary:
Primary
Product Type:
Antibody
Concentration:
1 mg/mL
Classification:
Polyclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
0.02M potassium phosphate with 0.15M NaCl and 0.01% sodium azide; pH 7.2
Gene Alias:
CRS6; odd-paired homolog; ZIC; Zic family member 1; Zic family member 1 (odd-paired homolog, Drosophila); zic protein member 1; ZIC1; Zinc finger protein 201; Zinc finger protein of the cerebellum 1; Zinc finger protein ZIC 1; ZNF201
Gene Symbols:
ZIC1
Content And Storage:
-20°C, Avoid Freeze/Thaw Cycles
Gene:
ZIC1