7192824

IL-33R (ST2) Monoclonal Antibody (RMST2-2), APC-eFluor™ 780, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

IL-33R (ST2)

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols

IL1RL1

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

IL1RL1

Clone

RMST2-2

Applications

Flow Cytometry

Conjugate

APC-eFluor 780

Host Species

Rat

Target Species

Mouse

Gene Accession No.

P14719

Gene ID (Entrez)

17082

Isotype

IgG2a κ

Purification Method

Affinity chromatography

Product Type

Antibody

Description

  • IL-33R, also known as ST2, is a receptor for IL-33
  • It is a member of the IL-1 receptor family of innate receptors
  • Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33
  • IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways
  • This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13
  • Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form
  • The membrane bound form can be released from the cell surface by proteolytic cleavage
  • The soluble forms have been suggested to act as decoys dampening the IL-33 signaling
  • IL-33R is primarily expressed by mast cells, basophils, and eosinophils
  • In mouse, IL-33R expression has been shown on ILC2 and Th2 cells
  • IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

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7192824

Rat Monoclonal Antibody...


Antigen:
IL-33R (ST2)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols:
IL1RL1

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IL1RL1

Clone:
RMST2-2

Applications:
Flow Cytometry

Conjugate:
APC-eFluor 780

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P14719

Gene ID (Entrez):
17082

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Antigen:
CD184 (CXCR4)

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
b2b220Clo; C Cmotif chemokine; C X C motif chemokine; CC motif chemokine; CCmotif chemokine; CD antigen CD184; CD184; CD184 antigen; chemokine (C-X-C motif) receptor 4; chemokine (C-X-C) receptor 4; chemokine receptor; chemokine receptor (LCR1); chemokine receptor 4; chemokine receptor CXCR4; Cmkar4; CXC; CXC chemokine receptor; C-X-C chemokine receptor type 4; CXC motif chemokine; C-X-C motif chemokine receptor 4; CXCR4; CXC-R4; CXCR-4; D2S201E; FB22; Fusin; HM89; HSY3RR; HUMSTR; LAP3; LAP-3; LCR1; LESTR; Leukocyte-derived seven transmembrane domain receptor; leukocyte-expressed seven-transmembrane-domain; lipopolysaccharide-associated protein 3; LPS-associated protein 3; neuropeptide Y receptor Y3; neuropeptide Y3 receptor; NPY3R; NPYR; NPYRL; NPYY3R; PB-CKR; PBSF/SDF-1; pre-B-cell-derived chemokine receptor; SDF-1 receptor; Sdf1r; seven transmembrane helix receptor; seven-transmembrane-segment receptor, spleen; stromal cell-derived factor 1 receptor; WHIM; WHIMS

Gene Symbols:
Cxcr4

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Cxcr4

Clone:
2B11

Applications:
Flow Cytometry

Conjugate:
APC-eFluor 780

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
P70658

Gene ID (Entrez):
12767

Isotype:
IgG2b κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

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Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
CD163; CD163 antigen; CD163 molecule; CD163v2; CD163v3; Hemoglobin scavenger receptor; M130; macrophage-associated antigen; MM130; putative CD163 antigen; SCARI1; Scavenger receptor cysteine-rich type 1 protein M130; sCD163; Soluble CD163; Soluble sCD163

Gene Symbols:
CD163

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD163

Clone:
TNKUPJ

Applications:
Flow Cytometry

Conjugate:
PE-eFluor 610

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q2VLH6

Gene ID (Entrez):
93671

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
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7192831

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Antigen:
CD33

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD33; CD33 antigen; CD33 antigen (gp67); CD33 molecule; CD33 molecule transcript; FLJ00391; gp67; Myeloid cell surface antigen CD33; p67; sialic acid binding Ig-like lectin 3; sialic acid-binding Ig-like lectin 3; SIGLEC3; Siglec-3

Gene Symbols:
CD33

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
CD33

Clone:
P67.6

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P20138

Gene ID (Entrez):
945

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
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