7193156

IL-33R (ST2) Monoclonal Antibody (hIL33Rcap), APC, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

IL-33R (ST2)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols

IL1RL1

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Clone

hIL33Rcap

Applications

Flow Cytometry

Conjugate

APC

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q01638

Gene ID (Entrez)

9173

Immunogen

Extracellular domain of human IL-33R protein

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

IL1RL1

Description

  • Description: This hIL33Rcap monoclonal antibody recognizes human IL-33R, also known as ST2
  • This antibody binds both, the membrane bound form (ST2L) and the soluble form (ST2S)
  • This antibody is suitable for both surface and intracellular staining
  • This hIL33Rcap clone is also used as a capture antibody in the IL-33R (ST2) Human ProcartaPlex™ Simplex Kit (Product # EPX010-12231-901) Applications Reported: This hIL33Rcap antibody has been reported for use in flow cytometric analysis
  • Applications Tested: This hIL33Rcap antibody has been pre-diluted and tested by flow cytometric analysis of LAD2 cells
  • This may be used at 5 μL (0.125 μg) per test
  • A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
  • Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
  • Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser IL-33R, also known as ST2, is a receptor for IL-33
  • It is a member of the IL-1 receptor family of innate receptors
  • Its extracellular domain consists of 3 Ig-like domains that directly interact with its co-receptor IL-1RAcP, and the ligand alarmin, IL-33
  • IL-33 ligation results in the association of IL-33R complex with its adaptor proteins MyD88, IRAK1, IRAK4 and TRAF6, and activation of the NF-kB, and MAPK pathways
  • This, in turn, instigates the release of chemokines and cytokines such as IL-5, IL-6, IL-8, and IL-13
  • Two most common isoforms of IL-33R that result from alternative splicing are ST2L – the membrane bound form, and ST2S – the soluble form
  • The membrane bound form can be released from the cell surface by proteolytic cleavage
  • The soluble forms have been suggested to act as decoys dampening the IL-33 signaling
  • IL-33R is primarily expressed by mast cells, basophils, and eosinophils
  • In mouse, IL-33R expression has been shown on ILC2 and Th2 cells
  • IL-33R signaling has been implicated in the number of immune conditions, including allergies, arthritis, atherosclerosis and sepsis.

Compare Similar Items

Show Difference

Img

Fischer Scientific

7193156

Mouse Monoclonal Antibody...


Antigen:
IL-33R (ST2)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
DER4; Fit1; Fit-1; Fos-responsive gene 1 protein; growth stimulation-expressed; homolog of mouse growth stimulation-expressed; IL-1 R4; IL1RL1; IL-1RL1; IL33R; IL-33R; interleukin 1 receptor like 1; interleukin 1 receptor-like 1; interleukin 1 receptor-related protein; Interleukin1 receptor like 1; interleukin-1 receptor-like 1; Interleukin-33 receptor alpha chain; Ly84; lymphocyte antigen 84; Protein ST2; Protein T1; sIL 33R; soluble IL 33 Receptor; soluble IL 33R; St2; ST2L; St2-rs1; ST2V; Ste2; T1; T1/ST2

Gene Symbols:
IL1RL1

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
hIL33Rcap

Applications:
Flow Cytometry

Conjugate:
APC

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q01638

Gene ID (Entrez):
9173

Immunogen:
Extracellular domain of human IL-33R protein

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IL1RL1

Img

Fischer Scientific

7193167

Mouse Monoclonal Antibody...


Antigen:
CD268 (BAFF Receptor)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
2010006P15Rik; B cell-activating factor receptor; BAFF receptor; BAFFR; BAFF-R; B-cell maturation defect; B-cell maturation defect 1; B-cell-activating factor receptor; Bcmd; Bcmd1; Bcmd-1; BLyS receptor 3; BR3; BROMIX; CD268; CVID4; Lvis22; prolixin; RGD1560810; TNF receptor superfamily member 13C; Tnfrsf13c; Tumor necrosis factor receptor superfamily member 13C; tumor necrosis factor receptor superfamily, member 13C

Gene Symbols:
TNFRSF13C

Isotype:
IgG2a κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
8A7

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96RJ3

Gene ID (Entrez):
115650

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
TNFRSF13C

Img

Fischer Scientific

7193169

Mouse Monoclonal Antibody...


Antigen:
CD42b

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
Antigen CD42b-alpha; BDPLT1; BDPLT3; BSS; CD42a; CD42B; CD42b-alpha; DBPLT3; Glycocalicin; glycoprotein 1b, alpha polypeptide; glycoprotein Ib (platelet), alpha polypeptide; glycoprotein Ib platelet alpha subunit; glycoprotein Ib platelet subunit alpha; glycoprotein Ibalpha; GP1B; GP1BA; GPIB; GPIb alpha; GP-Ib alpha; GPIbA; GPIbalpha; GPIX; GP-IX; MGC34595; mutant platelet membrane glycoprotein Ib-alpha; platelet glycoprotein Ib alpha chain; platelet glycoprotein Ib alpha polypeptide; Platelet GPIX; platelet membrane glycoprotein 1b-alpha subunit; platelet membrane glycoprotein Ib-alpha; VWDP

Gene Symbols:
Gp1ba

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
HIP1

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
P07359

Gene ID (Entrez):
2811

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Gp1ba

Img

Fischer Scientific

7193179

Mouse Monoclonal Antibody...


Antigen:
CD85j (ILT2)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
CD85 antigen-like family member J; CD85j; Ig-like transcript 2; ILT2; ILT-2; Immunoglobulin-like transcript 2; leucocyte Ig-like receptor B1; leukocyte immunoglobulin like receptor B1; leukocyte immunoglobulin-like receptor subfamily B member 1; leukocyte immunoglobulin-like receptor subfamily B member 1 soluble isoform; leukocyte immunoglobulin-like receptor subfamily B member 3-like; leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1; LILRB1; LIR1; LIR-1; LOC100912456; MIR7; MIR-7; Monocyte/macrophage immunoglobulin-like receptor 7; myeloid inhibitory receptor 7; PIRB; PIR-B

Gene Symbols:
LILRB1

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
HP-F1

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q8NHL6

Gene ID (Entrez):
10859

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
LILRB1