7193195

CD365 (TIM1) Monoclonal Antibody (1D12-TIM1), PE-Cyanine7, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

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Antigen

CD365 (TIM1)

Concentration

5 μL/Test

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias

AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols

Havcr1

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Clone

1D12-TIM1

Applications

Flow Cytometry

Conjugate

PE-Cyanine7

Host Species

Mouse

Target Species

Human

Gene Accession No.

Q96D42

Gene ID (Entrez)

26762

Immunogen

IgV domain of human CD365

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Havcr1

Description

  • Mouse Monoclonal Antibody CD365 also known as T-cell immunoglobulin and mucin domain 1 (Tim-1) is a type 1 surface glycoprotein that consists of extracellular N-terminal immunoglobulin V-like domain and a mucin domain, and a short cytoplasmic tail
  • The endogenous ligand for CD365 is Tim-4
  • In addition, CD365 is known to be a cellular receptor or co-receptor for a number of viruses including hepatitis A and C viruses, Ebola virus, Marburg virus, Dengue virus, Zika virus, West Nile virus, and Japanese encephalitis virus
  • The direct binding of the viruses by CD365 occurs via phosphatildyl-serine exposed on viral envelopes
  • Polymorphisms within human CD365 gene (HAVCR1) are associated with susceptibility to infection and the disease severity
  • CD365 has also been implicated in the T cell co-stimulation
  • CD365 is primarily expressed in epithelial cells
  • It is also highly expressed in A549, 769-P and Caco-2 and cell lines
  • CD365 exists also as a soluble protein generated by metalloproteinase mediated proteolytic cleavage of the surface protein.

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Img

Fischer Scientific

7193195

Mouse Monoclonal Antibody...


Antigen:
CD365 (TIM1)

Concentration:
5 μL/Test

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
AI503787; CD365; HAVCR; HAVCR1; HAVcr-1; Hepatitis A virus cellular receptor 1; hepatitis A virus cellular receptor 1 homolog; Kidney injury molecule 1; Kim1; KIM-1; T cell immunoglobin domain and mucin domain protein 1; t cell immunoglobulin and mucin domain-containing protein 1; T cell membrane protein 1; T-cell immunoglobulin and mucin domain containing 1; T-cell immunoglobulin and mucin domain-containing protein 1; T-cell immunoglobulin mucin family member 1; T-cell immunoglobulin mucin receptor 1; T-cell membrane protein 1; TIM; TIM1; TIM-1; TIMD1; TIMD-1

Gene Symbols:
Havcr1

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
1D12-TIM1

Applications:
Flow Cytometry

Conjugate:
PE-Cyanine7

Host Species:
Mouse

Target Species:
Human

Gene Accession No.:
Q96D42

Gene ID (Entrez):
26762

Immunogen:
IgV domain of human CD365

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Havcr1

Img

Fischer Scientific

7193197

Mouse Monoclonal Antibody...


Antigen:
CD25

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2

Gene Alias:
ADA; ADA1; Adenosine aminohydrolase; adenosine deaminase; CD25; CD25 antigen; cytokine receptor; IDDM10; IL 2 RA; IL 2 receptor; IL 2R; IL 2R subunit alpha; IL2 RA; IL2 RA antibody; IL2 receptor; il-2 receptor alpha; IL-2 Receptor alpha chain; IL-2 receptor alpha subunit; IL2 receptor subunit alpha; IL-2 receptor subunit alpha; IL2R; IL-2R alpha; IL-2R alpha chain; IL2R subunit alpha; IL-2R subunit alpha; Il2ra; IL-2RA; IL-2-RA; IL2-RA; Il2ra antibody; IL2RAC; IMD41; interleukin 2 receptor; interleukin 2 receptor alpha chain; interleukin 2 receptor subunit alpha; interleukin 2 receptor, alpha; interleukin 2 receptor, alpha chain; interleukin-2 receptor alpha; interleukin-2 receptor alpha chain; interleukin-2 receptor alpha subunit; interleukin-2 receptor beta chain; Interleukin2 receptor subunit alpha; interleukin-2 receptor subunit alpha; Ly-43; p55; p55 chain; sIL 2R; soluble IL 2 receptor; TAC antigen; TCGFR

Gene Symbols:
IL2RA

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
OX39

Applications:
Flow Cytometry

Conjugate:
Super Bright 436

Host Species:
Mouse

Target Species:
Rat

Gene Accession No.:
P26897

Gene ID (Entrez):
25704

Immunogen:
__

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
IL2RA

Img

Sigma Aldrich

71932

tested according to Ph. Eur....


Antigen:
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Concentration:
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Classification:
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Form:
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Regulatory Status:
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Formulation:
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Gene Alias:
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Purification Method:
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__

Clone:
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Applications:
__

Conjugate:
__

Host Species:
__

Target Species:
__

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
__

Primary or Secondary:
__

Content And Storage:
__

Gene:
__

Img

Sigma Aldrich

71932

tested according to Ph. Eur....


Antigen:
__

Concentration:
__

Classification:
__

Form:
__

Regulatory Status:
__

Formulation:
__

Gene Alias:
__

Gene Symbols:
__

Isotype:
__

Purification Method:
__

Product Type:
__

Clone:
__

Applications:
__

Conjugate:
__

Host Species:
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Target Species:
__

Gene Accession No.:
__

Gene ID (Entrez):
__

Immunogen:
__

Primary or Secondary:
__

Content And Storage:
__

Gene:
__