7193223

RELM alpha Monoclonal Antibody (DS8RELM), PerCP-eFluor™ 710, eBioscience™, Invitrogen™

Rat Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

RELM alpha

Concentration

0.2 mg/mL

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Formulation

PBS with 0.09% sodium azide; pH 7.2

Gene Alias

1810019L16Rik; cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Fizz1; Fizz-1; FIZZ2; found in inflammatory zone 1; Himf; HXCP2; Hypoxia-induced mitogenic factor; parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; RELM-alpha; RELMb; RELMbeta; RELM-beta; resistin like alpha; resistin-like alpha; Retnla; Xcp2

Gene Symbols

Retnla

Isotype

IgG1 κ

Purification Method

Affinity chromatography

Product Type

Antibody

Clone

DS8RELM

Applications

Flow Cytometry

Conjugate

PerCP-eFluor 710

Host Species

Rat

Target Species

Mouse

Gene Accession No.

Q9EP95

Gene ID (Entrez)

57262

Immunogen

Recombinant mouse RELM alpha protein

Primary or Secondary

Primary

Content And Storage

4° C, store in dark, DO NOT FREEZE!

Gene

Retnla

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Description

  • Rat Monoclonal Antibody RELM alpha, also known as Resistin-like alpha or FIZZ1, is a small cytokine (88 aminoacids, MW 9.4 kDa) produced mostly by macrophages
  • Its highest constitutive expression has been observed in small peritoneal macrophages, alveolar macrophages and adipose tissue macrophages
  • It is strongly induced by IL-4 and IL-13
  • Together with Arginase 1 and Ym-1, RELM alpha is considered one of the hallmarks of the M2 polarization of mouse macrophages, however, macrophages polarized with IL-10 (M2c) express neither RELM alpha nor Arginase 1
  • Also, the expression patterns of RELM alpha and Arginase 1 in untreated tissue macrophages significantly differ
  • Elevated levels of RELM alpha may indicate parasitic infection
  • Humans do not have RELM alpha gene but human Resistin resembles mouse RELM alpha in respect to sequence, tissue distribution and function
  • Other members of RELM family in mouse: RELM beta, RELM gamma and Resistin display different tissue distribution and functional properties
  • RELM alpha plays an important role in parasite infection, mucosal inflammation and allergy.

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7193223

Rat Monoclonal Antibody...


Antigen:
RELM alpha

Concentration:
0.2 mg/mL

Classification:
Monoclonal

Form:
Liquid

Regulatory Status:
RUO

Formulation:
PBS with 0.09% sodium azide; pH 7.2

Gene Alias:
1810019L16Rik; cysteine-rich secreted protein A12-gamma; Cysteine-rich secreted protein FIZZ1; Fizz1; Fizz-1; FIZZ2; found in inflammatory zone 1; Himf; HXCP2; Hypoxia-induced mitogenic factor; parasite-induced macrophage novel gene 1 protein; Pmng1; RELMa; RELMalpha; RELM-alpha; RELMb; RELMbeta; RELM-beta; resistin like alpha; resistin-like alpha; Retnla; Xcp2

Gene Symbols:
Retnla

Isotype:
IgG1 κ

Purification Method:
Affinity chromatography

Product Type:
Antibody

Clone:
DS8RELM

Applications:
Flow Cytometry

Conjugate:
PerCP-eFluor 710

Host Species:
Rat

Target Species:
Mouse

Gene Accession No.:
Q9EP95

Gene ID (Entrez):
57262

Immunogen:
Recombinant mouse RELM alpha protein

Primary or Secondary:
Primary

Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
Retnla

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Gene Alias:
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Gene Symbols:
Eomes

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Applications:
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Host Species:
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Target Species:
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Gene Accession No.:
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Gene ID (Entrez):
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Primary or Secondary:
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Content And Storage:
4° C, store in dark, DO NOT FREEZE!

Gene:
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Formulation:
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Gene Alias:
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Gene Symbols:
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Isotype:
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Target Species:
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Gene Alias:
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Gene Symbols:
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Isotype:
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Purification Method:
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Clone:
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Applications:
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Primary or Secondary:
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Content And Storage:
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Gene:
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