7193282
CD43 Monoclonal Antibody (4-29-5-10-21), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Antigen
CD43
Concentration
5 μL/Test
Classification
Monoclonal
Form
Liquid
Regulatory Status
RUO
Formulation
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Gene Symbols
SPN
Primary or Secondary
Primary
Content And Storage
4° C, store in dark, DO NOT FREEZE!
Gene
SPN
Clone
4-29-5-10-21
Applications
Flow Cytometry
Conjugate
APC
Host Species
Mouse
Target Species
Human, Non-human Primate
Gene Accession No.
P16150
Gene ID (Entrez)
6693
Isotype
IgG1 κ
Purification Method
Affinity chromatography
Product Type
Antibody
Description
- Description: The monoclonal antibody 4-29-5-10-21 reacts with human and non-human primate CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin
- CD43 is a sialomucin which, like many mucins, can have both adhesive and anti-adhesive functions
- Expression of CD43 is found on most leukocytes and a small subset of B lymphocytes
- Proteolytic processing upon activation decreases surface expression
- CD43 is involved in the activation of T cells, B cells, NK cells, and monocytes
- The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages
- Applications Reported: This 4-29-5-10-21 antibody has been reported for use in flow cytometric analysis
- Applications Tested: This 4-29-5-10-21 antibody has been pre-titrated and tested by flow cytometric anaylsis of normal human peripheral blood cells
- This can be used at 5 μL (0.125 μg) per test
- A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL
- Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test
- Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
- CD43 (leukosialin, sialophorin) is a transmembrane mucin-like protein with high negative charge, expressed on the surface of most hematopoietic cells
- CD43 contributes to a repulsive barrier that interferes with cellular adhesion, however, in certain cases also promotes leukocyte aggregation
- By interaction with actin-binding proteins ezrin and moesin CD43 plays a regulatory role in remodeling T-cell morphology and regulates cell-cell interactions during lymphocyte traffic
- CD43 signaling both enhances LFA-1 adhesiveness and counteracts LFA-1 induction via other receptors
- Expression of CD43 causes induction of functionally active tumor suppressor p53 protein, but in case of p53 and ARF deficiency CD43 promotes tumor proliferation and viability
- CD43 appears to be an important modulator of leukocyte functions
- Diseases associated with CD43 dysfunction include Wiscott-Aldrich Syndrome and Adenoid Basal Cell Carcinoma.
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Antigen: CD43
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: 3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Gene Symbols: SPN
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: SPN
Clone: 4-29-5-10-21
Applications: Flow Cytometry
Conjugate: APC
Host Species: Mouse
Target Species: Human, Non-human Primate
Gene Accession No.: P16150
Gene ID (Entrez): 6693
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD43
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
3E8 antigen; A630014B01Rik; B-cell differentiation antigen LP-3; CD43; CD43 cytoplasmic tail; CD43-ct; Galactoglycoprotein; GALGP; gpL115; Leukocyte sialoglycoprotein; leukosialin; leukosianin; LOC101120462; LOW QUALITY PROTEIN: leukosialin; Lsn; Lsn1; Ly48; Ly-48; Lymphocyte antigen 48; sialophorin; sialophorin (gpL115, leukosialin, CD43); sialophorin gpL115; SPN; W3/13 antigen
Gene Symbols:
SPN
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
SPN
Clone:
4-29-5-10-21
Applications:
Flow Cytometry
Conjugate:
APC
Host Species:
Mouse
Target Species:
Human, Non-human Primate
Gene Accession No.:
P16150
Gene ID (Entrez):
6693
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: CD42b
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: Antigen CD42b-alpha; BDPLT1; BDPLT3; BSS; CD42a; CD42B; CD42b-alpha; DBPLT3; Glycocalicin; glycoprotein 1b, alpha polypeptide; glycoprotein Ib (platelet), alpha polypeptide; glycoprotein Ib platelet alpha subunit; glycoprotein Ib platelet subunit alpha; glycoprotein Ibalpha; GP1B; GP1BA; GPIB; GPIb alpha; GP-Ib alpha; GPIbA; GPIbalpha; GPIX; GP-IX; MGC34595; mutant platelet membrane glycoprotein Ib-alpha; platelet glycoprotein Ib alpha chain; platelet glycoprotein Ib alpha polypeptide; Platelet GPIX; platelet membrane glycoprotein 1b-alpha subunit; platelet membrane glycoprotein Ib-alpha; VWDP
Gene Symbols: Gp1ba
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: Gp1ba
Clone: HIP1
Applications: Flow Cytometry
Conjugate: Super Bright 600
Host Species: Mouse
Target Species: Human
Gene Accession No.: P07359
Gene ID (Entrez): 2811
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
CD42b
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
Antigen CD42b-alpha; BDPLT1; BDPLT3; BSS; CD42a; CD42B; CD42b-alpha; DBPLT3; Glycocalicin; glycoprotein 1b, alpha polypeptide; glycoprotein Ib (platelet), alpha polypeptide; glycoprotein Ib platelet alpha subunit; glycoprotein Ib platelet subunit alpha; glycoprotein Ibalpha; GP1B; GP1BA; GPIB; GPIb alpha; GP-Ib alpha; GPIbA; GPIbalpha; GPIX; GP-IX; MGC34595; mutant platelet membrane glycoprotein Ib-alpha; platelet glycoprotein Ib alpha chain; platelet glycoprotein Ib alpha polypeptide; Platelet GPIX; platelet membrane glycoprotein 1b-alpha subunit; platelet membrane glycoprotein Ib-alpha; VWDP
Gene Symbols:
Gp1ba
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
Gp1ba
Clone:
HIP1
Applications:
Flow Cytometry
Conjugate:
Super Bright 600
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
P07359
Gene ID (Entrez):
2811
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: TCR V delta 1
Concentration: 5 μL/Test
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias: __
Gene Symbols: TRD
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: TRD
Clone: TS8.2
Applications: Flow Cytometry
Conjugate: PE-Cyanine7
Host Species: Mouse
Target Species: Human
Gene Accession No.: 0
Gene ID (Entrez): 6964
Isotype: IgG1 κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
TCR V delta 1
Concentration:
5 μL/Test
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with 0.2% BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
__
Gene Symbols:
TRD
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
TRD
Clone:
TS8.2
Applications:
Flow Cytometry
Conjugate:
PE-Cyanine7
Host Species:
Mouse
Target Species:
Human
Gene Accession No.:
0
Gene ID (Entrez):
6964
Isotype:
IgG1 κ
Purification Method:
Affinity chromatography
Product Type:
Antibody
Antigen: MHC Class I (H-2kb)
Concentration: 0.2 mg/mL
Classification: Monoclonal
Form: Liquid
Regulatory Status: RUO
Formulation: PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias: class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen
Gene Symbols: H2-K1
Primary or Secondary: Primary
Content And Storage: 4° C, store in dark, DO NOT FREEZE!
Gene: H2-K1
Clone: AF6-88.5.5.3
Applications: Flow Cytometry
Conjugate: Super Bright 702
Host Species: Mouse
Target Species: Mouse
Gene Accession No.: P01901, P03991, P04223, P14428
Gene ID (Entrez): 14972
Isotype: IgG2a κ
Purification Method: Affinity chromatography
Product Type: Antibody
Antigen:
MHC Class I (H-2kb)
Concentration:
0.2 mg/mL
Classification:
Monoclonal
Form:
Liquid
Regulatory Status:
RUO
Formulation:
PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Alias:
class I major histocompatibility antigen H-2Kd; H-2 class I histocompatibility antigen, K-B alpha chain; H-2 class I histocompatibility antigen, K-D alpha chain; H-2 class I histocompatibility antigen, K-K alpha chain; H-2 class I histocompatibility antigen, K-Q alpha chain; H-2 class I histocompatibility antigen, K-W28 alpha chain; H-2K; H2-K; H-2K(B); H-2K(d); H-2K(K); H-2K(Q); H2-K1; histocompatibility 2, K1, K region; K-f; MHC class I antigen; MHC class I H2-K-b-alpha-2 cell surface glycoprotein; MHC class I heavy chain H2-K; MHC H2-K transplantation antigen
Gene Symbols:
H2-K1
Primary or Secondary:
Primary
Content And Storage:
4° C, store in dark, DO NOT FREEZE!
Gene:
H2-K1
Clone:
AF6-88.5.5.3
Applications:
Flow Cytometry
Conjugate:
Super Bright 702
Host Species:
Mouse
Target Species:
Mouse
Gene Accession No.:
P01901, P03991, P04223, P14428
Gene ID (Entrez):
14972
Isotype:
IgG2a κ
Purification Method:
Affinity chromatography
Product Type:
Antibody