Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Feline Leukaemia Virus p15E
1 mg/mL
Immunohistochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Unconjugated
Mouse
Virus
Env polyprotein, Feline Leukemia Virus glycoprotein 70, Glycoprotein gp70 [Precursor], GP70 envelope protein, gp70 protein (SU), p15E protein, p15E protein (TM)
IgG2a
Protein A purified
NB100-65808 recognizes an epitope within the amino-terminal domain of both the 20kDa full-length (including intracellular sequence), and the 15kDa truncated forms, of feline leukaemia virus (FeLV) p15e transmembrane envelope protein. Persistent infection of cats with the oncoretrovirus FeLV can result in the non-neoplastic condition known as FeLV-associated enteritis (FAE). Studies have shown strong expression of the major FeLV proteins p15e and gp70 in intestinal crypt epithelial cells of cats with FAE, compared to FeLV-positive cats without intestinal alterations, thereby suggesting a pathogenic role for these envelope proteins/precursors in FAE.
PF6J-2A1
Western Blot 1:2000, Immunohistochemistry 1:10-1:500, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500
Monoclonal
Purified
RUO
Q85525
Made to Viral FELINE LEUKAEMIA VIRUS p15E
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.