Mouse Monoclonal Antibody
Manufacturer: Fischer Scientific
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Fc epsilon RI
1.0 mg/mL
Immunoprecipitation, Flow Cytometry, Immunocytochemistry, Immunofluorescence, ELISA, Western Blot
Unconjugated
Mouse
Apoptosis, Asthma, Cancer, Immunology, Signal Transduction
P12319
2205
Made to Human Fc EPSILON R1 ALPHA
Primary
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
90
Western Blot 1:100-1:2000, Flow Cytometry 1:50-1:100, ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:10-1:2000, Immunoprecipitation 1:10-1:500
Monoclonal
Purified
RUO
Human
alpha polypeptide, Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide, Fc-epsilon RI-alpha, FcERI, high affinity immunoglobulin epsilon receptor alpha-subunit, high affinity immunoglobulin epsilon receptor subunit alpha, high-affinity, of mast cells, alpha polypeptide
FCER1A
IgG2b
Protein G purified
NB100-63269 recognizes the human high affinity Fc receptor for IgE (Fc epsilon R1), which plays a central role in the IgE-mediated allergic response. Fc epsilon R1 consists of four subunits, a high affinity IgE binding alpha subunit, a beta chain and two di-sulphide linked gamma subunits. Clone 9E1 specifically recognizes the extracellular D1 domain of the Fc epsilon R1 alpha chain. Fc epsilon R1 is primarily expressed on mast cells and basophils but expression of Fc epsilon R1 has also been reported on monocytes, Langerhans cells and dendritic cells from patients with atopic diseases.