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7199565

NKG2D/CD314 Antibody (1D11) - Low Endotoxin, Azide and BSA Free, Novus Biologicals™

Mouse Monoclonal Antibody has been used in 3 publications

Manufacturer: Fischer Scientific

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Antigen

NKG2D/CD314

Concentration

1.0 mg/mL

Applications

Immunohistochemistry (Frozen), Functional Assay, CyTOF, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence

Conjugate

Unconjugated

Host Species

Mouse

Target Species

Human

Gene Alias

CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence

Gene Symbols

KLRK1

Isotype

IgG1

Purification Method

Protein A purified

Test Specificity

NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).

Clone

1D11

Dilution

Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay

Classification

Monoclonal

Form

Purified

Regulatory Status

RUO

Gene Accession No.

P26718

Gene ID (Entrez)

22914

Immunogen

NKL cells.

Primary or Secondary

Primary

Content And Storage

Store at -20C. Avoid freeze-thaw cycles.

Description

  • NKG2D/CD314 Monoclonal specifically detects NKG2D/CD314 in Human samples
  • It is validated for Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Paraffin, Immunohistochemistry-Frozen, CyTOF-ready, Functional Assay.

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Fischer Scientific

7199565

Mouse Monoclonal Antibody has been ...

Antigen:
NKG2D/CD314
Concentration:
1.0 mg/mL
Applications:
Immunohistochemistry (Frozen), Functional Assay, CyTOF, Immunohistochemistry, Immunoprecipitation, Immunocytochemistry, Flow Cytometry, Immunohistochemistry (Paraffin), Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Human
Gene Alias:
CD314, CD314 antigen, D12S2489E, FLJ17759, FLJ75772, Killer cell lectin-like receptor subfamily K member 1, killer cell lectin-like receptor subfamily K, member 1, KLR, NK cell receptor D, NKG2-D, NKG2-D type II integral membrane protein, NKG2-D-activating NK receptor, NKG2DDNA segment on chromosome 12 (unique) 2489 expressed sequence
Gene Symbols:
KLRK1
Isotype:
IgG1
Purification Method:
Protein A purified
Test Specificity:
NB100-65956 is specific for CD314, also known as natural killer receptor G2 (NKG2D) and as killer cell lectin-like receptor subfamily K, member 1 (KLRK1). CD314 is a C-type lectin-like activating receptor which is expressed on most natural killer (NK) cells, CD8 T cells and gamma delta T cells. CD314 forms homodimers that signal through an associated DAP10 adaptor protein. Ligands of CD314 include MICA, MICB and UL16 binding protein (ULBP), which are inducibly expressed. Ligand binding to CD314 results in NK cell activation and potent costimulation of effector T cells. Clone 1D11 is reported to inhibit T cell recognition of MICA (1,6).
Clone:
1D11
Dilution:
Flow Cytometry 1:50-1:200, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500, CyTOF-ready, Functional Assay
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Gene Accession No.:
P26718
Gene ID (Entrez):
22914
Immunogen:
NKL cells.
Primary or Secondary:
Primary
Content And Storage:
Store at -20C. Avoid freeze-thaw cycles.

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Fischer Scientific

7199568

Rabbit Polyclonal Antibody...

Antigen:
RNMT (p Tyr1003)
Concentration:
__
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rabbit
Target Species:
Human
Gene Alias:
DKFZp686H1252, EC 2.1.1.56, hcm1p, hCMT1, hCMT1c, hMet, KIAA0398, mRNA (guanine-7-)methyltransferase, mRNA (guanine-N(7)-)-methyltransferase, mRNA cap guanine-N7 methyltransferase, mRNA cap methyltransferase, RG7MT1MET, RNA (guanine-7-) methyltransferase
Gene Symbols:
RNMT
Isotype:
IgG
Purification Method:
Affinity Purified
Test Specificity:
Recognizes Met phosphorylated on Tyr1003.
Clone:
__
Dilution:
Western Blot 1:100-1:2000
Classification:
Polyclonal
Form:
__
Regulatory Status:
RUO
Gene Accession No.:
P08581
Gene ID (Entrez):
8731
Immunogen:
Peptide corresponding to amino acid region encompassing the human, mouse, and rat phospho-Met (Tyr1003).
Primary or Secondary:
Primary
Content And Storage:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

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Fischer Scientific

7199570

Rat Monoclonal Antibody...

Antigen:
TGF-beta RII
Concentration:
LYOPH
Applications:
Western Blot
Conjugate:
Unconjugated
Host Species:
Rat
Target Species:
Mouse
Gene Alias:
AAT3, EC 2.7.11, EC 2.7.11.30, FAA3, HNPCC6, LDS1B, LDS2B, MFS2, RIIC, TAAD2, tbetaR-II, TGF-beta receptor type II, TGF-beta receptor type IIB, TGF-beta receptor type-2, TGF-beta type II receptor, TGFbeta-RII, TGFR-2, transforming growth factor beta receptor type IIC, transforming growth factor, beta receptor II (70/80kDa), transforming growth factor, beta receptor II (70/80kDa) isoform 1, transforming growth factor, beta receptor II (70/80kDa) isoform 2, transforming growth factor, beta receptor II (70-80kD), Transforming growth factor-beta receptor type II
Gene Symbols:
TGFBR2
Isotype:
IgG2
Purification Method:
__
Test Specificity:
__
Clone:
RM0132-6G11
Dilution:
Western Blot 1:500-1:1000
Classification:
Monoclonal
Form:
Purified
Regulatory Status:
RUO
Gene Accession No.:
Q62312
Gene ID (Entrez):
7048
Immunogen:
__
Primary or Secondary:
Primary
Content And Storage:
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Img

Fischer Scientific

7199572

Mouse Monoclonal Antibody...

Antigen:
Campylobacter Jejuni
Concentration:
1 mg/mL
Applications:
Immunocytochemistry, Immunohistochemistry, Immunohistochemistry (Frozen), ELISA, Immunofluorescence
Conjugate:
Unconjugated
Host Species:
Mouse
Target Species:
Bacteria
Gene Alias:
Campilobacter
Gene Symbols:
__
Isotype:
IgM
Purification Method:
Ammonium sulfate precipitation
Test Specificity:
NB100-65039 reacts with C. jejuni type 1 (K807, K858, K634), C. coli, C. hyointestinalis, C. lardis, C. jejuni type 2. It cross reacts with S. aureus and weakly with P. fluorescens. NB100-65039 reacts with a soluble excreted antigen in EIA. This antibody is unaffected by frozen storage of specimens, unlike antibodies to flagellar antigens which require fresh cultured organisms.
Clone:
BGN/2E-10
Dilution:
ELISA 1:100-1:2000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification:
Monoclonal
Form:
Precipitation
Regulatory Status:
RUO
Gene Accession No.:
__
Gene ID (Entrez):
__
Immunogen:
Native, Type 1
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.