Antigen:
Coagulation Factor III/Tissue Factor
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry, Western Blot, Immunofluorescence, Immunocytochemistry, Flow Cytometry
Target Species:
Primate, Human
Gene Alias:
CD142, CD142 antigen, Coagulation factor III, coagulation factor III (thromboplastin, tissue factor), FLJ17960, TF, TFA, Thromboplastin, tissue factor
Purification Method:
Protein G purified
Test Specificity:
CD142, also known as Tissue Factor, is the membrane receptor for coagulation factors VII and VIIa and is the cell surface initiator of coagulation. It is the major molecule of this type and is criticial for controlling hemostasis, thrombosis and inflammation. NB100-65221 is specific for an epitope within the extracellular domain, epitope locus I. It recognizes both the reduced and native non-reduced human and primate tissue factors. It does not inhibit coagulation or neutralize factor VII binding to CD142.
Dilution:
Western Blot 1-10 ug/ml, Flow Cytometry 1:10-1:1000, Immunohistochemistry 1:10-1:500, Immunocytochemistry/Immunofluorescence 1:10-1:500, Immunohistochemistry-Frozen 1:10-1:500
Classification:
Monoclonal
Research Discipline:
Cancer
Immunogen:
Denatured Tissue factor isolated from human brain by the Factor VII affinity method.
Primary or Secondary:
Primary
Content And Storage:
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.