72-013-3

HRX Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 72-013-3-Each-of-1 In Stock ₹ 42,908.34

72-013-3 - Each of 1

₹ 42,908.34

In Stock

Quantity

1

Base Price: ₹ 42,908.34

GST (18%): ₹ 7,723.501

Total Price: ₹ 50,631.841

Antigen

HRX

Classification

Polyclonal

Conjugate

Unconjugated

Gene

KMT2A

Gene Alias

6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4297

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration

0.5 mg/mL

Formulation

PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.

Q03164

Gene Symbols

KMT2A

Immunogen

Protein corresponding to Human KMT2A (aa 700-1000)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
  • The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
  • The purified antibody is tested for its functionality in various relevant research applications
  • The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
  • This antibody is predicted to react with Monkey, Equine, Pig, Bovine, Rabbit, Rat and Mouse
  • KMT2A is a histone methyltransferase that plays an essential role in early development and hematopoiesis
  • It is a catalytic subunit of the MLL1/MLL complex, a multiprotein complex that mediates both methylation of 'Lys-4' of histone H3 (H3K4me) complex and acetylation of 'Lys-16' of histone H4 (H4K16ac)
  • In the MLL1/MLL complex, KMT2A specifically mediates H3K4me, a tag for epigenetic transcriptional activation
  • KMT2A has weak methyltransferase activity by itself, and requires other components of the MLL1/MLL complex to obtain full methyltransferase activity
  • It has no activity toward histone H3 phosphorylated on 'Thr-3', less activity toward H3 dimethylated on 'Arg-8' or 'Lys-9', and has higher activity toward H3 acetylated on 'Lys-9'
  • Required for transcriptional activation of HOXA9 and promotes PPP1R15A-induced apoptosis.

Compare Similar Items

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Thermo Scientific

72-013-3

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Antigen:
HRX

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KMT2A

Gene Alias:
6430520K01; ALL1; ALL-1; CDK6/MLL fusion protein; C-terminal cleavage product of 180 kDa; CXXC7; CXXC-type zinc finger protein 7; histone-lysine N-methyltransferase 2A; histone-lysine N-methyltransferase MLL; HRX; HTRX; HTRX1; Kmt2a; lysine (K)-specific methyltransferase 2A; lysine methyltransferase 2A; lysine N-methyltransferase 2A; mixed lineage leukemia 1; mKIAA4050; Mll; MLL cleavage product C180; MLL cleavage product N320; MLL/ENL fusion protein; MLL/GAS7; MLL/GAS7 fusion protein; MLL/GMPS fusion protein; MLL/hCDCrel fusion protein; MLL1; MLL1A; MLL-AF4 der(11) fusion protein; MLL-AF9; Myeloid/lymphoid or mixed-lineage leukemia; myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); myeloid/lymphoid or mixed-lineage leukemia 1; myeloid/lymphoid or mixed-lineage leukemia protein 1; N-terminal cleavage product of 320 kDa; p180; p320; rearranged MLL protein; TET1-MLL; trithorax Drosophila; trithorax-like protein; TRX1; WDSTS; zinc finger protein HRX

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4297

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q03164

Gene Symbols:
KMT2A

Immunogen:
Protein corresponding to Human KMT2A (aa 700-1000)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

72-014-0

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Antigen:
PRMT1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PRMT1

Gene Alias:
6720434D09Rik; ANM1; arginine N-methyltransferase 1; AW214366; HCP1; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; histone-arginine N-methyltransferase PRMT1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; HMT1 hnRNP methyltransferase-like 2; HMT1 hnRNP methyltransferase-like 2 isoform 3; HMT2; Hrmt1l2; interferon receptor 1-bound protein 4; IR1B4; Mrmt1; PRMT1; protein arginine methyltransferase 1; protein arginine N-methyltransferase 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3276

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q99873

Gene Symbols:
PRMT1

Immunogen:
Protein corresponding to Human PRMT1 (aa 165-356)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

72-014-6

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Antigen:
RNF20

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RNF20

Gene Alias:
4833430L21Rik; AW540162; BRE1; BRE1 E3 ubiquitin ligase homolog; BRE1A; BRE1-A; C79397; E3 ubiquitin-protein ligase BRE1A; FLJ11189; FLJ20382; hBRE1; HNF3B; homolog of S. cerevisiae BRE1; hypothetical protein; KIAA2779; Kiaa4116; MGC129667; MGC129668; mKIAA4116; RCJMB04_5a23; RING finger protein 20; ring finger protein 20, E3 ubiquitin protein ligase; RING-type E3 ubiquitin transferase BRE1A; Rnf20; TCF3B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
56254

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
Q5VTR2

Gene Symbols:
RNF20

Immunogen:
Recombinant protein corresponding to Human RNF20 (aa 96-433)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Non-human Primate

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

72-015-2

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Antigen:
FOXN1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXN1

Gene Alias:
D11Bhm185e; Fkh19; FKHL20; forkhead box N1; forkhead box protein N1; FOXN1; Hepatocyte nuclear factor 3 forkhead homolog 11; Hfh11; HFH-11; HNF-3/forkhead homolog 11; JTK1; nu; nude; Rnu; RONU; Rowett nude; WHN; winged helix nude; winged-helix nude; winged-helix transcription factor nude

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287469, 8456

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.5 mg/mL

Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2

Gene Accession No.:
O15353

Gene Symbols:
FOXN1

Immunogen:
Peptide pair corresponding to Human FOXN1 (aa 377-395; 633-646)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG