72-029-5
MC4R Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | 72-029-5-Each-of-1 | In Stock | ₹ 42,908.34 |
72-029-5 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,908.34
GST (18%): ₹ 7,723.501
Total Price: ₹ 50,631.841
Antigen
MC4R
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MC4R
Gene Alias
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
4160
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.
P32245
Gene Symbols
MC4R
Immunogen
Peptide corresponding to Human MC4R (aa 20-34)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides
- The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide
- The purified antibody is tested for its functionality in various relevant research applications
- The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature
- This antibody is predicted to react with Monkey, Cat and Pig
- Expression of MC4R has been reported in brain
- Unlike the other melanocortin receptors, MC4R is not expressed in adrenal cortex or in melanocytes
- G-protein Coupled Receptors (GPCRs) comprise one of the largest families of signaling molecules with more than a thousand members currently predicted to exist
- All GPCRs share a structural motif consisting of seven membrane-spanning helices, and exist in both active and inactive forms
- An array of activating ligands participate in the conformation of GPCRs which leads to signaling via G-proteins and downstream effectors
- Ongoing studies have also shown the vast series of reactions which participate in the negative regulation of GPCRs
- This "eturn-off"e activity has tremendous implications for the physiological action of the cell, and continues to drive pharmacological research for new drug candidates
- Two blockbuster drugs which have been developed as GPCR-targeted pharmaceuticals are Zyprexa (Eli Lilly) and Claritin (Schering-Plough) which have multi-billion dollar shares of the mental health and allergy markets, respectively.
Compare Similar Items
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Antigen: MC4R
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MC4R
Gene Alias: MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4160
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.: P32245
Gene Symbols: MC4R
Immunogen: Peptide corresponding to Human MC4R (aa 20-34)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
MC4R
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MC4R
Gene Alias:
MC4; MC4 receptor; mc4r; Mc4-r; melanocortin 4 receptor; melanocortin receptor 4; si:dkey-151m6.62; zMC4
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
4160
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P32245
Gene Symbols:
MC4R
Immunogen:
Peptide corresponding to Human MC4R (aa 20-34)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Calcitonin Receptor
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CALCR
Gene Alias: C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116506, 12311, 799
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.: P30988, P32214, Q60755
Gene Symbols: CALCR
Immunogen: Peptide corresponding to Human CALCR (aa 490-508)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Calcitonin Receptor
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CALCR
Gene Alias:
C1A/C1B; calcitonin receptor; CALCR; Clr; COPT1; CRT; CT receptor; CTR; CT-R; CTR1; hCTR1
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116506, 12311, 799
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.:
P30988, P32214, Q60755
Gene Symbols:
CALCR
Immunogen:
Peptide corresponding to Human CALCR (aa 490-508)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZO-3
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TJP3
Gene Alias: tight junction protein 3; tight junction protein 3 (zona occludens 3); tight junction protein ZO-3; TJP3; TJP-3; ZO3; ZO-3; Zona occludens protein 3; zonula occludens protein 3
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 27134
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.: O95049
Gene Symbols: TJP3
Immunogen: Recombinant protein corresponding to Human TJP3 (aa 700-909)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ZO-3
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TJP3
Gene Alias:
tight junction protein 3; tight junction protein 3 (zona occludens 3); tight junction protein ZO-3; TJP3; TJP-3; ZO3; ZO-3; Zona occludens protein 3; zonula occludens protein 3
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
27134
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.2
Gene Accession No.:
O95049
Gene Symbols:
TJP3
Immunogen:
Recombinant protein corresponding to Human TJP3 (aa 700-909)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: GFI1b
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GFI1B
Gene Alias: BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 8328
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 0.5 mg/mL
Formulation: PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.: Q5VTD9
Gene Symbols: GFI1B
Immunogen: Protein corresponding to human GFI1b (aa21-aa170)
Quantity: 100μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
GFI1b
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GFI1B
Gene Alias:
BDPLT17; GFI1B; Gfi-1B; growth factor independent 1B; growth factor independent 1B (potential regulator of CDKN1A, translocated in CML); growth factor independent 1B transcription repressor; growth factor independent 1B transcriptional repressor; growth factor independent 1B-like protein; growth factor independent protein 1B; growth factor-independent 1B; Potential regulator of CDKN1A translocated in CML; Zinc finger protein Gfi-1b; ZNF163B
Host Species:
Rabbit
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
8328
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
0.5 mg/mL
Formulation:
PBS with 0.1% BSA, 30% glycerol and 0.09% sodium azide; pH 7.4
Gene Accession No.:
Q5VTD9
Gene Symbols:
GFI1B
Immunogen:
Protein corresponding to human GFI1b (aa21-aa170)
Quantity:
100μg
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG