7214617

TNF Mouse, anti-Human, R718, Clone: MAB11, BD Horizon™

Mouse Monoclonal Antibody

Manufacturer: Fischer Scientific

The price for this product is unavailable. Please request a quote

Antigen

TNF

Applications

Flow Cytometry

Conjugate

R718

Host Species

Mouse

Target Species

Human

Content And Storage

Refrigerate Upon Arrival

Clone

MAB11

Classification

Monoclonal

Form

Liquid

Regulatory Status

RUO

Primary or Secondary

Primary

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Description

  • Description The MAb11 monoclonal antibody specifically binds to human tumor necrosis factor (TNF, also known as TNF-α) protein
  • TNF is an efficient juxtacrine, paracrine and endocrine mediator of inflammatory and immune functions
  • It regulates the growth and differentiation of a variety of cell types
  • TNF is cytotoxic for transformed cells when in conjunction with IFN-γ
  • It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts
  • The immunogen used to generate the MAb11 hybridoma was recombinant human TNF
  • The MAb11 antibody has been reported to crossreact with Rhesus Macaque TNF.

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